​Sickle Cell Disease Regional Care Excellence (SoRCE) Program

The Sickle Cell Disease Regional Care Excellence Program (SoRCE) aims to enhance the health outcomes of individuals with sickle cell disease (SCD) by broadening access to quality care and monitoring quality of life indicators. With around 100,000 people affected in the United States, early treatment is crucial to prevent or reduce severe complications such as painful episodes, silent strokes, and early mortality. Despite newborn screening, less than half of children with SCD receive the necessary treatment, and challenges persist as these patients transition into adolescence and adulthood, partly due to ongoing provider education on emerging therapies. The program is structured into seven regions, each led by a Regional Coordinating Hub (RCH) that partners with clinical and community organizations within its area. These hubs drive continuous quality improvement initiatives focused on increasing access to care and elevating treatment standards for SCD patients. Administered by the Health Resources and Services Administration under the Department of Health and Human Services, the program emphasizes collaborative regional efforts to address gaps in care and improve long-term health outcomes for individuals living with sickle cell disease.