This Pre-Solicitation opportunity from Department Of Health And Human Services was posted on June 2, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.
Krauzlis Electrophysiology Recording System
Contract Overview
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The contract seeks to acquire a state-of-the-art electrophysiological recording system to support the Visual Circuits Section of the Laboratory of Sensorimotor Research at the National Eye Institute. This advanced system is intended to significantly enhance the lab's ability to record neural activity from large populations of neurons simultaneously during visual and visually guided behavioral tasks. The contractor is responsible for delivering, installing, configuring, demonstrating, and supporting a fully operational system that includes high-channel-count neural recording capabilities, along with compatible probes, electronics, software, necessary licenses, documentation, training, and accessories. The motivation behind this acquisition stems from the critical role of central visual pathways in sensory-motor coordination and visual processing, which are essential for everyday functions and are implicated in various disorders such as cerebral visual impairment, attention deficit disorders, and Parkinson’s disease. Current equipment in the lab supports only up to 64 recording channels, whereas the new system will enable recording from hundreds of neurons simultaneously, opening new avenues for advanced research into how the brain processes visual information. This effort is part of the lab’s broader goal to understand the brain systems behind vision and develop innovative therapies for related neurological disorders. The acquisition is set as a Total Small Business Set-Aside and will be performed at the NIH facility in Bethesda, Maryland.
General Info
Agency
NAICS
Place of Performance
Bethesda, MD, 20892, USASet-Aside
Timeline
Submission Closed
Organization & Contact Information
Full Description
Purpose. The purpose of this acquisition is to obtain a complete electrophysiological recording system that will enhance the capability of the Visual Circuits Section, Laboratory of Sensorimotor Research (LSR), National Eye Institute Intramural Research Program, to record from large populations of neurons simultaneously during visual and visually guided behavioral tasks.
Acquisition outcome. The contractor shall deliver, install, configure, demonstrate, and support a fully functional electrophysiology recording system capable of simultaneous high-channel-count neural recording, including compatible probes, electronics, software, licenses, documentation, training, and accessories necessary for operation.
Specification / Configuration
Background Information:
Good vision depends critically on the brain's central pathways that process visual information and control the movements of our eyes, head, and body. These central visual pathways underlie our ability to perform routine yet sophisticated acts of sensorimotor coordination, such as reading a book, preparing a meal with family, walking down the street, or recognizing a friend. Conversely, problems with these central pathways are responsible for some of the most common, disruptive, and costly visual dysfunctions, as evident in cerebral visual impairment, attention deficit disorders and Parkinson’s disease, among others.
The goal of the Laboratory of Sensorimotor Research (LSR) is to understand the brain systems that underlie visual abilities, to identify how abnormalities in these visual circuits can cause disorders of sensory-motor coordination, perception, and cognition, and to use this knowledge to develop novel and more effective therapies. A fundamental technique for advancing our understanding is to record from identified neurons in the brain while subjects process visual information and perform visually guided tasks.
Recently, modern technologies have made it possible to record from hundreds of neurons simultaneously, which can provide a dramatically more detailed picture of the patterns of neuronal activity in the brain. This more detailed picture opens new possibilities for solving basic problems about how the brain codes and processes visual information. The current electrophysiological recording (“ephys”) systems we have in the lab can accommodate up to 32 or 64 recording channels. The purpose of this acquisition is to update or replace one of these systems with a modern system capable of recording from hundreds of neurons simultaneously.