NAVIGATE Reproductive Center of Excellence (Network for Assessment, Validation, Innovation, Guidance, Access, Treatment and Evaluation)

The Office of the Assistant Secretary for Health’s Office on Women’s Health is soliciting applications through a cooperative agreement to establish a Center of Excellence under the NAVIGATE Reproductive Center of Excellence initiative, aimed at reducing diagnostic delays and improving care coordination for critical reproductive health conditions including polyendocrine metabolic ovarian syndrome, endometriosis, uterine fibroids, infertility, pelvic inflammatory disease, reproductive-age endocrine disorders, and recurrent miscarriage. This opportunity, identified by solicitation number WH-AST-26-003 and Assistance Listing 93.088, is open to organizations with demonstrated expertise in prevention, diagnosis, and treatment of these conditions, with the goal of translating evidence into practice, standardizing root-cause clinical pathways, expanding workforce training, and improving health outcomes for women. Applicants must align their proposals with Make America Healthy Again (MAHA) priorities, focusing on prevention, early diagnosis, evidence-based clinical practice, patient-centered care, and scalable interventions, and are expected to deliver a comprehensive work plan that includes launching an expanded pilot, initiating baseline data collection, publishing a toolkit, and submitting a finalized dissemination and sustainability plan. The total period of performance is up to two years, structured in annual budget periods, with an optional competitive third year contingent on successful progress and submission of a non-competing continuation application. Proposals must be submitted via Grants.gov by July 24, 2026, and must adhere to strict formatting requirements including 8.5” x 11” page size, 12-point font in Times New Roman or Arial, and acceptable file formats such as PDF or Word; submissions in Excel, compressed files, or password-protected documents will be disqualified. Applications must include a complete Project Narrative, Appendices with resumes, organizational charts, and letters of commitment, and a fully justified Budget Package. Evaluations will be scored on a 100-point scale across six weighted factors: Need and Population Impact (30 points), Project Design and Approach (25 points), Organizational Capacity and Expertise (15 points), Evaluation and Performance Measurement (15 points), Training and Dissemination (10 points), and Budget Justification (5 points). Applicants must pass three mandatory gates—Responsiveness Review, Programmatic Technical Review, and Risk Assessment—which evaluate legal compliance, technical feasibility, financial stability, past performance, and management capability. Awards are subject to a $500,000 ceiling per award, require active SAM.gov