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66 -- Custom Laser System

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263-2007-Q-DT-0196Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

AI Contract Overview

The National Institute on Deafness and Other Communication Disorders (NIDCD) intends to procure a custom laser scanning system from Mike's Machine Company that is compatible with their existing multiple custom laser systems to ensure continuity and consistency in ongoing research. This custom instrument is designed to be mounted on an Olympus BX51WI microscope, accommodating an Olympus fluorescence condenser and integrating several key optical components, including Cambridge Optical scanning galvanometers and an Olympus pupil transfer lens. It also features a precision translation stage compatible with the Olympus BX51WI, capable of submicron specimen positioning for highly delicate cellular recording and imaging. The translation stage’s stepper motors are to be interfaced with a modified Sutter MP285 controller for automated, computer-controlled movement in three dimensions. The system is engineered to combine two-photon laser scanning fluorescence microscopy with electrophysiological patch-clamp recordings, incorporating custom optical components developed through collaboration with an experienced machinist to interface an infrared Ti-Sapphire pulsed-laser with the microscope. The custom software created by the users will manage imaging and electrophysiological data acquisition. Although Mike's Machine Company is currently the sole manufacturer of this specialized equipment, the NIH has stated this is not a solicitation for competitive proposals but will consider statements of capabilities in writing from any other party who believes they can meet the detailed technical requirements. Contact information for inquiries has been provided, emphasizing written communication only.

General Info

NIDCD orders custom laser scanning system with integrated optics and precision stage from Mike's Machine.

Agency

N/A

NAICS

334516 - Analytical Laboratory Instrument Manufacturing

Place of Performance

Not specified

Set-Aside

NONE

Documents

No documents available

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Timeline

PostedAug 21

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Organization & Contact Information

AgencyN/A

Contacts1 person available

OfficeN/A

Organization / Agency

N/A

Office AddressN/A

Contacts

Lloyd - GarnesPurchasing Agent

contact@example.gov

+1 (555) 000-0000

Full Description

The National Institutes of Health(NIH)National Institute on Deafness(NIDCD)intends to procure from Mike's Machine Company the following: We are currently using multiple custom laser scanning systems from Mike?s Machine Company and we would like this instrument to be compatible with them, allowing us to maintain experimental consistency with previous research. Mike's Machine Company is the sole manufacturer of this equipment. These instruments will be a base instrument for an elaborate custom designed system and should adhere to the following specifications. Requirements: 1. The Custom Laser System must mount on the base of an Olympus BX51WI and allow installation of an Olympus fluorescence condenser on its upper surface. 2. The Custom Laser System must allow installation of Cambridge Optical 6210 (4mm) scanning galvanometers. 3. The system must allow installation of the Olympus FV-PL-W3 pupil transfer lens. 4. The translation stage must be physically compatible with the Olympus BX51WI microscope and allow specimen placement with submicron precision for cellular recording and imaging. 5. The Translation stage stepper motors must interface with the Sutter MP285 controller for automated computer control of specimen movement in x, y, and z axes. 6. The Sutter MP285 controller must be modified for use with stepper motors present in the translation stage (TS-BX51WI). enables combined two-photon laser scanning fluorescence microscopy with electrophysiological (patch-clamp) recordings. I (Stephan Brenowitz) have collaborated with a precision machinist (Tim Lafratta) at Mike?s Machine Company to design custom optical components that interface between an infrared Ti-Sapphire pulsed-laser and Olympus BX51WI upright microscope for laser-scanning microscopy. In addition the system includes a custom translation stage and controller that are designed to be used with the scan system and microscope and work with custom software that we have written for computer control of imaging and electrophysiology data acquisition. we are currently using multiple custom laser scanning systems from Mike?s Machine Company and we would like this instrument to be compatible with them, allowing us to maintain experimental consistency with previous research. This is not a solicitation for competitive proposals however, if any other interested party believes that it can meet the requirements it may submit a statement of capabilities. The capability statment and any other information furniished must be in writing, and must contain material in sufficeint detail to allow NIH to determine if the party meets all of the foregoing requirements. If you have any questions please contat Lloyd Garnes at 301-402-3341 or email at garnesl@od.nih.gov. Collect calls will not be accepted.