6640--Sioux Falls Health Care System - Brand Name or Equal Supply Procurement of DORIC Fiber Photometry System

Sources Sought Notice
Sources Sought Notice
Page 4 of 4 Sources Sought Notice
Sources Sought Notice
Page 1 of 4 The Sioux Falls Health Care System requires the purchase of a Fiber Light Source & Photometry Console with the salient characteristics listed below.
This is a SOURCES SOUGHT NOTICE only looking for American manufactured equipment as listed below for market research purposes. No proposals are being requested or accepted with this notice. THIS IS NOT A SOLICITATION FOR PROPOSALS OR PRICING AND NO CONTRACT SHALL BE AWARDED FROM THIS NOTICE. This notice shall not be construed as a solicitation or as an obligation on the part of the Department of Veterans Affairs. The Buy American Act, FAR 52.225-1, applies. Interested vendors shall include the place of manufacture in their responses. Responses to this notice will be treated only as information for the Government to consider as part of their market research efforts. The information provided will be used by the Government in developing its acquisition strategy regarding possible set aside for Veteran Owned and other socio-economic categories of small business. Interested parties are responsible for adequately marking proprietary, restricted or competition sensitive information contained in their response. The Government does not intend to pay for the information submitted in response to this notice and parties responding will not be entitled to payment for direct or indirect costs incurred in responding to this notice. The North American Industry Classification System (NAICS) code for this requirement is 334516 Surgical Appliance and Supplies Manufacturing with an SBA Small Business Size Standard of 1,000 employees. The deadline for this information is 4:00 PM Central Time on Thursday, December 19, 2025.
(Functional/Performance/Specification (Brand Name or Equal)) This requirement includes meeting Brand Name or equal to the DORIC Fiber Photometry system. The system includes Behavior & Bundle Photometry Console (BBC300), Fiber Photometry with Fluorescence Mini Cubes, Fiber Photometry with Rotary Fluorescence Mini Cube, Bundle-imaging Fiber Photometry, Wireless Photometry, Rotary Bundle-imaging Fiber Photometry, FluoPulse system, Doric Neuroscience Studio V6 software, Danse software, and Fiber Photometry Accessories.
Fiber photometry monitors neuronal activity in the brain of freely moving behaving animals that helps correlate brain functioning with animal behavior. It uses implanted fiber-optic cannula to deliver excitation light to a group of neurons labeled with genetically encoded calcium indicators and detect their calcium-related fluorescence fluctuations. While it lacks the cellular/spacial resolution of a miniature fluorescence microscope, fiber photometry uses a relatively simple setup to record fluctuations in the calcium activity of a group of neurons in behaving animals. A smaller cannula's fiber diameter is better suited for deep tissue neuronal activity monitoring than a somewhat larger lens of miniature fluorescence microscopes.
Optogenetics uses light to control the activity of specific neurons that have been genetically modified to express light sensitive proteins. Allows researchers to turn neurons on or off based on cell type, enabling causal investigation of neural circuit function. Used to test the role of specific neural pathways in complex behaviors like aggression, anxiety, and sleep. Allows for precise control over when and where neural activity is manipulated.
Integrating fiber photometry and optogenetics using specialized software allows for simultaneous recording of neural activity and optogenetic stimulation in freely moving animals. Allows researchers to correlate specific neural activity patterns with specific behaviors. Enables the design of more complex and comprehensive experiments to probe neural circuits.
Sioux Falls VA Health Care System requires the following:
QTY 1: Behavior & Bundle Photometry Console Must have at least 4 x USB 3.0 ports Must have at least 4 x Camera Trigger ports Must have at least 4 x Analog Outputs (for light source control) Must have at least 8 x Digital Input/Output (DIO) ports Must have at least 24 additional Digital ports (8x inputs/outputs, 8x inputs, 8x outputs) with the extension board
QTY 1: 4 laser diodes Fiber Light Source - 4x 638nm - 80 mW, LDFLS-4CH and 4x 450nm - 75 mW, LDFLS-4CH Must meet the following laser diode and fiber light criteria: Optical Fiber: Multimode 50 m Power stability: < 1% over 1 hour with the following Operating Modes: OFF, Continuous, External TTL, External Analog, Computer (USB) TTL Modulation: HI > 2.8 V, LOW < 2.3 V Analog Modulation: 0 - 5 V (80 mA / V and 75mA/ V) Rise / Fall time: < 10 µsec Max modulation frequency: 10 kHz
QTY 4: Mono Fiberoptic Patchcord, MFP_200/220/LWMJ-0.22_1m_FC-FCA Must meet the following Fiber-optic capability: 200/220/900-0.37 or Core ( m): 200, Cladding ( m): 220, Buffer: 245, Jacket: 900, NA: 0.37
QTY 1: Branching Box for HD9 pattern - 9 FC inputs, 1 HD9 output Must have at least 9 input ports Must be compatible with FC Input Optical Connector Must be compatible with HD9 Output Optical Connector Must have the following dimension, 211 x 94 x 45 mm
QTY 1: Bundle-imaging Fiber Photometry Cube with Targeted Optogenetics Must have a wavelength range of 350 to 1100 nm Must have a field of view (FOV) of Ø3 mm Must have an objective numerical aperture (NA) of 0.40 LEDs Excitation Uniformity must be 80% over FOV Optogenetics Excitation Uniformity must be 65% over FOV Optogenetics Crosstalk between fibers must be >31 dB Must have optical fiber compatibility with the following fiber optic core diameter 200 or 400 µm and NA 0.37 Must be able to measure spectral bandwidth within the following 3 excitation and 2 emission ranges: Excitation #1: 405-410, 410-415, 421-433 or 433-445nm Excitation #2: 460-490 nm Excitation #3: 555-570 nm Emission #1: 500-540 nm Emission #2: 580-600 nm Optical filter attenuation must be > Optical Density (OD) 5 outside band Must be compatible with HD7, HD9 or HD19 Optical fiber connectors. Dimensions must be 220mm x 220mm x 59mm Must have a CMOS (Complementary Metal-Oxide Semiconductor) image sensor Must provide 1024x1024 px resolution Must provide Pixels size down to 5.86 µm x 5.86 µm Must have a frame rate up to 60 Hz Must have a USB 3.0 Computer interface.
QTY 1: High Density Fiberoptic Patch cord - Low Autofluorescence
QTY 8: Ferrule Connector (FC)/Ferrule Connector (FC) Mating Adapter Round
QTY 8: Fiberoptic Rotary Joint, pigtailed with 400 um, NA0.37 fibre, 1.0m input, 0.15m output, optimized for fiber photometry
QTY 8: Gimbal holder for FRJ 1x1_PT-G2 - ID 19 mm Must have 96 mm x 69 mm x 25 mm dimensions
QTY 8: Mono Fiberoptic Patchcord - Low AutoFluorescence Must have the following Fiber-Optic Codes to ensure system compatibility Optical Fiber Type: Silica/Silica Core: Glass Cladding: Glass Numerical Aperture: 0.22-0.37 Flexibility: Good Auto-Fluorescence: Excellent Core Diameter ( m): 400 Cladding ( m): 440 Buffer ( m): 470 NA: 0.37 Must have the following Jacket Codes to ensure system compatibility. Composition Code: 1100 Description: Hytrel loose tube 1.1 mm Color: Black OD (mm): 1.1 Linear Mass (g/m): 0.5
Must be compatible with the following Connectors: 1st Connector Code: FCM (Flexible metal conduit) 1st Connector Description: FC Connector with Metal Ferrule 2nd Connector Code: MF1.25(F) 2nd Connector Description: Metal Ferrule OD 1.25 mm with Flange
QTY 10: Zirconia Sleeve 1.25 mm with black cover Must have a Ferrule Diameter of 1.25mm
QTY 30: Mono Fiberoptic Cannula Fiber-Optic must be made from Silica/Silica material Fiber-Optic type must be 400( m) NA 0.37 Fiber Lenth must 5.0mm Receptacle must be a male to female (MF) 1.25 Fiber tip must be flat (FLT)
QTY 2: Stereotaxic Cannula Holder 1.25 mm Ferrule diameter must be 1.25mm Rod diameter must be 6.3 mm
QTY 1: CamLoop with RGB camera and Wide-Angle lens, Behavior tracking System for closed loop stimulation Must be able to provide 1440 x 1080 px (1.6MP) resolution Must have dynamic range of 12 bits Must provide gain range of 0 to 48 dB Must be able to provide a Frame rate of at least 60 fps at full resolution Sensor format: 1 / 2.9'' Must have a USB 3.0 Interface Minimum exposure of 1 ms or less Lens must be mounted using C-mount or CS-mount
QTY 1: Danse 3-year subscription, Data Analysis Software, 1 license
QTY 1: Gentec-EO Pronto-SI Power Meter + SM1 Treaded adaptor + 2.5mm receptacle + 1.25mm, receptacle
QTY 1: High performance workstation set up for Doric's systems Must have an Intel Core i9 13th gen. 24-core processor or better Must have a minimum RAM of 2x32GB DDR5 5600 Must have GeForce RTX 3060 12GB DDR6 or better graphic card to accurately capture and measure video files. Must have SSD 4TB NVMe + Hard Drive 4TB or better to support the software and system. Must be Win11 Pro compatible to run the system software.
QTY 1: Assisted 2x2 Fiber-optic Rotary Joint, 400 um NA0.37 fibre, 1m input, optimized for fiber photometry Part # AFRJ_2x2_PT_400-0.37
QTY 1: Base Station for wireless fiber photometry system Must have a transmission range up to 2 meters Must be able to accommodate 4 headstages Must operate within 2.4 - 2.5 GHz wireless frequency band. Base Station Interface must be compatible with HDMI (to NC500) or USB-B (to BBC300)
QTY 1: Wireless Photometry Headstage - ferrule 2.5 mm - 1 integrated photodetector and 2 integrated LEDs. With a 40mAh battery
QTY 1: Battery Charger for wireless fiber photometry - Part # WiFP_CHRG Must Interface with a USB-C Power Supply: 1 meter cable USB-C to USB-A Must have a capacity of 4 headstages
QTY 10: Multi Fluid Injections Cannulas, OmFC_ZF1.25_400/470-0.37_5.0mm_FLT_4.9mm_PLGS
QTY 10: OmFC Fluid Injector Part # FI_OmFC-ZF_140/190_5.1mm
QTY 10: Mono Fiberoptic Cannula Part # MFC_400/430-0.37_5mm_ZF2.5_FLT
QTY 1: Co-Extruded PE/PVC Tubing for HRJ-OL Part# HRJ-OL _BTCOEX_25Ga_clear (2 meters)