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A -- NIMH Toxicological Evaluation of Novel Ligands Program

Awarded

NIMH-08-DN-00011Federal

Submission Closed06/30/2009, 12:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541712

DIBBS

ADAPTER SET, GROUND HAN

Solicitation # SPE8EF-27-T-0079

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DEADLINE

Solicitation # SPE7M4-27-T-0909

Solicitation SPE7M4-27-T-0909 is a Total Small Business Set-Aside issued by the DLA Weapons Support Fluid Handling Division for the procurement of five lower cam assemblies, identified by NSN 1710-01-478-1569. The requirement specifies parts from The Boeing Company (P/N 74A430615-1001) or Safran Landing Systems Canada Inc (P/N 74A430615-1001). This is a critical application item with a required delivery date of April 28, 2029, and a need ship date of March 1, 2029. Delivery is established as FOB Origin under the First Destination Transportation program, with the final destination being DLA Distribution San Diego. The contract mandates strict adherence to quality and security standards, including CMMC Level 2 Self-Assessment and the protection of covered defense information. Packaging must comply with ASTM D3951 and MIL-STD-129, with DLA Master List requirements taking precedence. Inspection and acceptance will occur at the destination based on zero-based sampling plans such as MIL-STD-1916 or ASQ H1331. Notably, the government will not evaluate or award to offers utilizing additive manufacturing processes. All payment requests and receiving reports must be processed electronically through the Wide Area WorkFlow system.

DLA WEAPONS SUPPORT FLUID HANDLING DIVISION

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Specialized Aerospace Technical ConsultingThe Specialized Aerospace Technical Consulting subcontract, issued by the National Aeronautics and Space Administration Space Technology Mission Directorate, focuses on supporting prime contractors for NASA Innovative Advanced Concepts Phase I projects. The scope of work involves performing technical feasibility assessments, mathematical modeling, and theoretical analysis to validate TRL 2 concepts. Key activities include conducting scientific research, developing conceptual designs, and performing trade studies to advance disruptive aerospace innovations. Qualified providers must possess deep expertise in advanced physics, orbital mechanics, or other disruptive aerospace technologies. The primary deliverables for this engagement are comprehensive technical reports and detailed feasibility analyses. Interested parties should note the response deadline of October 28, 2026, for this specialized technical services opportunity.

Space Technology Mission Directorate

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European Southern Observatory (ESO) AccessThis subcontract involves the provision of specialized astronomical data collection and observation services to support prime contractors working on UKRI ESRC Explore Award research projects. The scope of work centers on the utilization of large-scale astronomical telescopes and sensors through the European Southern Observatory to deliver high-quality observational imagery and comprehensive astronomical data sets. All activities must be conducted in strict adherence to the observation proposal and access standards established by the European Southern Observatory. Managed under the Economic and Social Research Council within UK Research and Innovation, the contract is categorized under NAICS code 541712 and was posted on September 7, 2026.

Economic and Social Research Council (ESRC)

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XMaS Facility Beamline AccessThis subcontract involves the provision of X-ray diffraction and spectroscopy services for prime contractors working on UKRI ESRC Explore Award research projects. The work is conducted using synchrotron X-ray beamlines at the X-ray Materials Science Facility located at the ESRF, requiring strict adherence to all ESRF access protocols. The primary objective of the agreement is the delivery of high-quality X-ray diffraction patterns and spectroscopic data. Managed under the Economic and Social Research Council within UK Research and Innovation, the contract falls under NAICS code 541712 and was posted on September 7, 2026.

Economic and Social Research Council (ESRC)

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SuperSTEM Facility AccessThis subcontract agreement establishes a partnership to provide high-resolution electron microscopy imaging and analysis for prime contractors working on UKRI ESRC Explore Award research projects. The services are facilitated through the EPSRC UK National Facility for Advanced Electron Microscopy, known as SuperSTEM, which provides the necessary advanced electron microscopes and technical infrastructure for detailed sample analysis. Under the terms of the agreement, all work must adhere to the established SuperSTEM facility guidelines. The primary deliverables include comprehensive microscopy data, high-resolution imaging results, and detailed analysis reports. This arrangement ensures that researchers have access to specialized scientific instrumentation required to meet the objectives of their ESRC-funded projects.

Economic and Social Research Council (ESRC)

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Biophysics and Non-Optical Signal IntegrationThis subcontract for the Defense Advanced Research Projects Agency focuses on the development and integration of massless external trigger mechanisms, specifically utilizing focused ultrasound or magnetic fields, for projects within the Biological Technologies Office. The scope of work involves designing the interface between physical signals and protein domains while defining the kinetic limitations of signal transfer across cell membranes. The project requires specialized expertise in sonogenetics or magnetogenetics to deliver comprehensive technical specifications and validation of the trigger mechanisms. Interested parties must respond by December 31, 2026, under NAICS code 541712.

Defense Advanced Research Projects Agcy

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Vehicle Recompete: IGF::OT::IGF DESIGN, DEVELOPMENT, DEMONSTRATION, AND INTEGRATION OF ENHANCED… — INDEFINITE DELIVERY / INDEFINITE QUANTITY W9113M13R0012This Indefinite Delivery Indefinite Quantity contract, managed by the Department of the Army, focuses on the design, development, demonstration, and integration of enhanced warfighter capabilities to meet operational and developmental needs. The vehicle is currently in a pre-forecast stage for a full recompete, with the existing ordering period set to expire on December 16, 2027. There are currently 13 active task orders with a total value of approximately 285.75 million dollars distributed among four companies. Radiance Technologies Inc is the primary contractor, holding the majority of the value through efforts centered on High Energy Laser components, system integration, and beam control technologies. Other significant contributors include Serco Inc, which provides technology development support for the Reagan Test Site, and BlueHalo LLC.

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VCA Clinical Outcome Assessment ToolsThis subcontract, titled VCA Clinical Outcome Assessment Tools, is issued by the Department of the Army USAMRRA under the Department of Defense. The primary objective is to develop tools and metrics to measure the success and functional outcomes of VCA procedures for prime contractors working on Defense Health Agency research projects. This involves the design of both quantitative and qualitative tools specifically focused on quality of life assessments and return-to-duty metrics. The project requires strict adherence to 32 CFR 219.104 regulations regarding human subject research. The final deliverable for this effort is a validated scoring system or outcome measurement tool. The contract is categorized under NAICS code 541712 and was posted on May 29, 2026.

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Deep Technology R&D Subaward (Drug Delivery Systems)The Deep Technology R&D Subaward for Drug Delivery Systems is a small business set-aside subcontract under the National Science Foundation. The selected provider will perform specialized research, laboratory analysis, and technical development to support prime contractors. Key responsibilities include conducting R&D experiments, creating prototypes or proof-of-concept models, and analyzing the commercial potential of new drug delivery methods. The contractor must possess the necessary laboratory facilities and biochemical analysis tools to execute the work and must ensure full compliance with 2 CFR section 200.332. Final deliverables consist of comprehensive research reports, validated prototypes, and detailed technical data. This opportunity is specifically reserved for small businesses with fewer than 500 employees, adhering to SBIR/STTR mandates under NAICS code 541712.

National Science Foundation

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Clinical Trial & Research Site Management (CRO)This subcontract focuses on the administration and execution of clinical trials for Department of Defense research projects specifically targeting Traumatic Brain Injury. The scope of work involves recruiting Service Members, Veterans, and DOW beneficiaries, managing clinical site operations, and implementing Community-Based Participatory Research through the use of electronic data capture systems. The contractor is required to maintain strict adherence to Good Clinical Practice, obtain IRB approval, and ensure full HIPAA compliance. The primary deliverables for this engagement include comprehensive clinical trial data sets and detailed participant outcome reports. This effort is managed under the Department of the Army and falls under NAICS code 541712.

Department Of The Army -- Usamraa

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DEADLINE

Vehicle Recompete: Bpa 75N98022A00040This Blanket Purchase Agreement, identified as 75N98022A00040, provides scientific support services for the National Eye Institute under the Department of Health and Human Services. Managed by the National Institutes of Health Olao, the contract has an established ceiling value of $45,226,230.52 and is classified as a full-recompete. The current ordering period for this vehicle is scheduled to conclude on September 15, 2027. The contract supports various specialized technical roles, with significant task order activity involving Astrix Technology, LLC. Notable service areas include genetic counseling, program management, operations and project management, and adaptive optics technical support. While the contract maintains a high ceiling for diverse scientific requirements, current active task order valuations are listed at zero, though historical task orders show individual values ranging from approximately $394,000 to nearly $491,000.

National Institutes Of Health Olao

POSTED

7 months ago

DEADLINE

N/A

AI Contract Overview

The National Institute of Mental Health is seeking proposals for the Toxicological Evaluation of Novel Ligands Program under solicitation NIMH-08-DN-00011. The primary objective of this contract is to assess target-selective ligands for PET, SPECT, and MRI imaging, as well as novel psychoactive agents for clinical research and therapeutic use. The resulting toxicology and safety data are intended to support Investigational New Drug applications to the FDA or evaluations by the Radioactive Drug Research Committee for human studies. The scope of work is divided into four key areas: analytical chemistry, pharmacokinetics and bioavailability, preliminary safety assessment, and IND-directed toxicity assessments including safety pharmacology. The anticipated contract structure consists of a three-year base period with two optional one-year extensions. This opportunity is open to all responsible sources through full and open competition.

General Info

Agency

N/A

Contract Value

$1,687,752.64

NAICS

541712 - Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology)

Place of Performance

NIMH R&D Contracts Management Branch6001 Executive Blvd, Rm 8154 Rockville, MD 20852 20852, CA, USA

Set-Aside

NONE

Awardee

SRI INTERNATIONAL

Award Issued Date

06/30/2009, 12:00:00 AM UTC

Documents

No documents available

Documents will appear here when they are available.

AI Contract Breakdown

Uniform Contract Format

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Timeline

3 updates

PhaseAwarded

PostedMar 10

Presolicitation

Deadline changedApr 7

Response deadline changed from May 30, 2008 to May 22, 2008.

Notice updatedApr 7

The notice description changed.

Notice updatedApr 8

Notice details unchanged. Attachments may have changed.

Type ChangedApr 10

Presolicitation → Solicitation

AwardedJun 30

Contract was awarded

Submission Closed

06/30/2009, 12:00:00 PM UTC

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Organization & Contact Information

AgencyN/A

Contacts2 people available

OfficeN/A

Organization / Agency

N/A

Office AddressN/A

Contacts

Phil Hastings-TickerhoffContracting Officer

contact@example.gov

+1 (555) 000-0000

Bruce E. AndersonContracting Officer

contact@example.gov

+1 (555) 000-0000

Full Description

The National Institute of Mental Health (NIMH) proposes to issue a Request for Proposals (RFP) No. NIMH-08-DN-00011 entitled "NIMH Toxicological Evaluation of Novel Ligands Program" under Full and Open Competition. The objective of resultant contract is to provide assessment of promising, target-selective ligands for PET, SPECT, and MRI imaging in humans, as well as limited assessment of novel psychoactive agents for clinical research and as potential therapeutics. Toxicology and safety data generated by the program are used to support Investigational New Drug (IND) applications to the Food and Drug Administration, or for Radioactive Drug Research Committee (RDRC) evaluation of a compound for human studies. Services to be provided under this program fall into four general areas: 1) analytical chemistry; 2) pharmacokinetics and bioavailability; 3) preliminary safety assessment; and 4) IND-directed toxicity assessments, including safety pharmacology. A three (3) year base contract with two (2), one (1) year options is contemplated. Plans are to award a contract by Sept 16, 2008. RFP No. NIMH-08-DN-00011 will be available on or about March 31, 2008 and the receipt date of proposals on or about May 30, 2008. The RFP may be accessed through http://www.fedbizopps.gov. Please note that the RFP for this requirement will include the Statement of Work, Deliverables, and Reporting Requirements, the Technical Evaluation Criteria, and proposal preparation instructions. All information required for the submission of an offer will be contained in the electronic RFP package. Following proposal submission and the initial review process, offerors comprising the competitive range will be requested to provide additional documentation to the Contracting Officer. All responsible sources are encouraged to submit a proposal that will be considered by the NIMH. This advertisement does not commit the Government to award a contract. Please contact Mark Lohrmann, Contracting Officer at 301-443-8886 or lohrmannm@mail.nih.gov for further information.

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