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Auto Droplet Generator

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NIDDK07396Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

General Info

Agency

Department Of Health And Human ServicesView Agency

NAICS

334516 - Analytical Laboratory Instrument ManufacturingView NAICS

Place of Performance

Bethesda, MD, 20892, USA

Set-Aside

NONE

Documents

(1)

PCA-NIDDK-07396+NOI.docx

DOCX

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services
Contacts1 person available
OfficeWashington, DC, 20201, USA
Organization / Agency
Department Of Health And Human Services
View Agency Profile
Office AddressWashington, DC, 20201, USA
Contacts

Full Description

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The Diabetes Molecular Genetics Section of the Phoenix Epidemiology and Clinical Research Branch at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) studies pancreatic islet organoids derived from induced pluripotent stem cells to investigate molecular pathways associated with type 2 diabetes. The laboratory recently acquired a QX600 Droplet Digital Polymerase Chain Reaction system to generate cell type-specific gene expression data, perform methylation analysis for epigenomic studies, and estimate pancreatic islet composition using cell type-specific marker genes.


Currently, the laboratory uses a Manual Droplet Generator to prepare samples for droplet digital polymerase chain reaction analysis. Although the system can process up to eight samples at a time, preparation of a full 96-well plate is time-consuming and relies heavily on manual pipetting.


The Auto Droplet Generator shall automate droplet generation for droplet digital polymerase chain reaction workflows, reduce hands-on processing time, and improve throughput and consistency across experiments involving pancreatic islets and islet organoids.

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