BIACORE

This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6, as supplemented with additional information included in this Notice. This announcement constitutes the only solicitation: quotes are being requested and written solicitation will not be issued. Solicitation number 12612120Q0023 is issued as a request for quote (RFQ). The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2020-07. This solicitation will be 100% Total Full and Open. The associated NAICS code is 334513, with a size standard 750 people and the PSC code is 6680 Define Minimum Requirements: Our major requirements is to assess the ligand-analyte interaction in label free manner. With the availability of vast collection of sensor chips will help our research and thus help us to elucidate specific ligand-analyte interactions. Includes integrated tutorials within software-availability of various sensor chips (such as dextran, GST,NTA, PEG, biotin, streptavidin, protein A, G and L, mouse and human antibody) provide optimized assay protocols that minimize the need for assay development (guided workflows include pre-programmed settings for all available capture kits and sensor chip surfaces detection technology is surface plasmon resonance (SPR) biosensor for comprehensive, label-free analysis and characterization of biomolecular interactions (ligand-analyte) in real-time. -sample type includes: LMW drug candidates to high molecular weight proteins in various sample Environments (also DNA, RNA, polysaccharides, lipids, cells, and viruses) -measurement of ligand-analyte interactions in buffer solutions or in crude environments such as serum -pre-programmed workflows for supporting kits, surfaces and reagents -automated unattended operation up to 24 hrs through workflows and wizards -molecular weight detection to include down to 100 Da in various sample environments 15-sample single run capacity -injection volume: 5-90ul -required sample volume 20-30ul -analysis time per cycle: 2-15 min -analysis temperature: 4-40'C -includes in-line (integrated) buffer degassing . Detection limits: ka 103 - 107 M-1s-1 kd 10-5 - 0.1 s-1 KD 100 uM to 1 pM MW 100 Da Kinetics can be ran in single or multicycle cycle -concentration analysis is with standard calibration curve or option of calibration free concentration Analysis -detection limit to include: 0.1nM for> 10000 Da analytes and 1nM for< 10 000 Da analytes -sample Refractive index range is 1.33 to 1.40 -baseline noise is <0.1 RU (RMS) -baseline drift is <0.3 RU/min -data is presented in result tables, result plots and real-time monitoring of sensor grams -information provided includes kinetic and affinity data specificity, selectivity, concentration Measurements - Optimized kits are already available to minimize the need for assay development -includes a PC for data handling and storage Descriptions: BR 110073 BC X100 PROCESSING UNIT BR 100798 Biacore x100 plus package 2925114 instrument Control Package 110v 19244701 Mians Cable 115v 29061864 Biacore X100 36 MONTH WARRANTY (24 MONTH EXT.) 3PMs included This acquisition is for the following items as identified in the Contract Line Item To be eligible, all vendors must be registered in the System for Award Management (SAM) with a current and active registration. A vendor can contact SAM by calling +1 (555) 000-0000 or e-mail at www.sam.gov. NO EXCEPTIONS. A DUNS (Dun and Bradstreet) number is required in order to register in SAM. Vendor must include their DUNS# on their capability statements. The NAICS code for the expected acquisition is 334513, with a Size Standard of 750 people and the PSC Code is 6680. Any subsequent procurement will be conducted as a commercial item purchased in accordance with FAR Part 12 and as a Simplified Acquisition Procedure in accordance with FAR Part 13. The Contractor shall provide all items F.O.B: destination. Location of the Government site is aboard USDA ARS Ames, IA and will be identified in the contract. The Government anticipates award of the Firm Fixed Price Contract. Submitting a Quote: To be eligible for an award, all contractors must be registered in the System for Award Management (SAM) with a current and active registration. A contractor can contact SAM by calling +1 (555) 000-0000 or e-mail at www.sam.gov. NO EXCEPTIONS. A DUNS (Dun and Bradstreet) numbers is required in order to register. Vendor must also include their DUNS # on their quote. Invoices are to be submitted and payments will be made through the IPP system. Vendors must be register or register in the IPP system. Offerors responding to this announcement shall submit their quote on SF-18 (SEE ATTACHED).The quote should include all fees, delivery charges and or surcharges. Only electronic submissions will be accepted. Please email all quotes in writing on the sf-18 to contact@example.gov by no later than Sept 1, 2020 at 11:00am Central Standard Time Questions in regards to this combined synopsis must be submitted through email and are due no later than 12:00pm CST on Aug 28 2020. Answers to any questions received by that time will be posted as an amendment to this combined synopsis/solicitation