Custom chemical synthesis

The National Institutes of Health Olao, under the Department of Health and Human Services, has issued a Notice of Intent to award a Firm-Fixed-Price Purchase Order for custom chemical synthesis to Cyclope Bio SL in support of the Synthetic Bioactive Molecules Section’s preclinical research. The requirement centers on the procurement of 200 grams of (1S,2S)-trans-N-Boc-1,2-cyclopentanediamine, a chemical precursor essential for synthesizing cyclopentane peptide nucleic acids and incorporating them into phytolodies to advance the project to the next stage of development. The place of performance is designated as Llanera, 33428, though the period of performance and delivery schedule remain unspecified. The solicitation number is 75N98026Q00593, with a NAICS code of 325199, and no set-aside provisions apply. Although the contract type is firm-fixed-price, the full value of the award is not disclosed. While the notice is not a competitive solicitation, it invites eligible small businesses—including 8(a), service-disabled veteran-owned, HUBZone, small disadvantaged, veteran-owned, and women-owned small businesses—to submit written capability statements demonstrating their ability to fulfill the requirement by 11:00 p.m. EDT on June 18, 2026. Responses must be emailed to david.shen@nih.gov, the primary point of contact. No inspection criteria, packaging specifications, evaluation factors, or contractual clauses are included in the notice, as it serves solely as a pre-solicitation announcement and does not constitute a formal request for proposals or binding contract terms.