DRAGEN Bio-IT Processor

(i) "This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued." (ii) The solicitation number is HHS-NIH-NHLBI-CSB-(HG)-2017-091-DM and the solicitation is being posted as a request for proposal (RFP): DRAGEN Bio-IT Processor on behalf of National Institutes of Health, National Human Genome Research Institute, (NHGRI); NO REFURBISHED OR USED SYSTEMS WILL BE ACCEPTED. (iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-94,2005-95, January 19, 2017. (iv) This is NOT a set-aside, the associated NAICS Codes: 334516, Analytical Laboratory Instrument Manufacturing and small business size standards is 1,000. The acquisition is being conducted in accordance with the procedures of FAR Part 12 and FAR Part 13. All responsible offerors may submit a proposal, which if timely received, shall be considered by the agency. Offers are due by 7:30 A.M. Eastern Time (EST) on March 27, 2017. Proposals can be emailed to the Contracting Officer, Dorothy Maxwell, Contracting Officer at maxwelld@mail.nih.gov, place Solicitation Number: HHS-NIH-NHLBI-CSB-(HG)-2017-096-DM on the quotation. (v) Background: The National Institutes of Health (NIH) mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability. The National Human Genome Research Institute (NHGRI) mission has expanded to encompass a broad range of studies aimed at understanding the structure and function of the human genome and its role in health and disease. NHGRI supports the development of resources and technology that will accelerate genome research and its application to human health. A critical part of the NHGRI mission continues to be the study of the ethical, legal and social implications (ELSI) of genome research. NHGRI also supports the training of investigators and the dissemination of genome information to the public and to health professionals. The NHGRI Undiagnosed Disease Program (UDP) is a program designed to address the needs of persons with debilitating medical conditions for which no diagnosis has been found despite an extensive workup. The goals of the UDP include finding accurate diagnoses and discovering new diseases that provide insight into human physiology and genetics. The UDP was established to evaluate participants who have undiagnosed medical conditions. Participants in the program have generally received extensive diagnostic workups before traveling to the NIH and often have numerous and/or complex medical problems. UDP Goals seek to (1) provide answers to patients with mysterious conditions that have long eluded diagnosis; and (2) advance medical knowledge about rare and common diseases. Purpose and Objectives: The purpose of this requirement is to procure "DRAGEN a BIO-IT Processor". The platform will provide an alternative to the CIT high performance computing center when the UDP needs resources beyond its CIT allocation. In addition, it will allow reduced turnaround time for the research re-analysis of previously negative genomic studies, and iterative analyses that would be impractical using standard methods. Procurement: 1. DRAGEN (NIH Level 3 throughput), Throughput usage equal to 14, 400 genomes and 28,800 exomes, based on genomes @40X coverage and exomes at 150X coverage. 2. DRAGEN Integrated Server (System can be used with or without connecting to external network). Anticipated Period of Performance: This is a single point-in-time hardware purchase; Delivery Upon Award. CIT Co-Location CSA Attn: NHGRI/ Co-Location team 12 South Drive Building 12 B Loading Dock Bethesda, MD 20892 Deliverables: 1. The DRAGEN server, a computer containing specialized hardware for the rapid processing genomic analyses. 2. Licensing to allow the processing of up to 14,000 40x genomes, 28,000 150x exomes, or a combination of these totals. 3. As is customary for many types of computer equipment, the platform has a defined useful life (in this case 4 years). vi. Include on the RFP, Contractor's Name, Contractor's Address, DUNS, TIN or EIN Number, Solicitation Number, Email Address, Contact Number, Discount. vii. The FAR Provision 52.212-1, Instructions to Offerors -- Commercial, applies to this acquisition and is hereby incorporated by reference. All Federal Acquisition Regulations (FAR) clauses may be viewed at http://acquisition.gov/comp/far/index.html. EVALUATION OF PROPOSALS: The Government will evaluate proposals that are determined technically acceptable in accordance with the Technical Evaluation factors. The Government intends to award a single contract from this solicitation. The Government reserves the right not to award a contract. Evaluation of Proposals: The Government reserves the right to make an award without discussions based solely upon initial proposals. Price (This will be Firm-Fixed Price): An evaluation of the offeror's price proposal will be made to determine if proposed prices are realistic for the work to be performed, reflect a clear understanding of the requirements, and are consistent with the technical proposal. Reasonableness determinations will be made by determining if competition exists, by comparing proposed prices with established commercial or GSA price schedules (if applicable), and/or by comparing proposed prices with the Independent Government Cost Estimate (IGCE). viii. The FAR Provision 52.212-1, Instructions to Offerors -- Commercial, applies to this acquisition and is hereby incorporated by reference. All Federal Acquisition Regulations (FAR) clauses may be viewed at http://acquisition.gov/comp/far/index.html. The proposal must reference the RFP Number: HHS-NIH-NHLBI-CSB-(HG)-2017-091-DM. All responsible offerors may submit a proposal, which if timely received, shall be considered by the agency. All proposals shall contain the following: 1. Name of Contracting Organization; 2. Solicitation number; 3. Contract Type; 4. Total Contract Value and Discounts; 5. Description of Requirement; 6. North American Industry Classification System (NAICS) Code; and 7. DUNS, TIN or EIN Number. x. In accordance to FAR clause 52.212-2, Evaluation - Commercial Items xi. In accordance with FAR Clause 52.212-3, Offeror Representations and Certifications - Commercial Items, offerors must complete annual representations and certifications on- line at https://www.sam.gov/portal/public/SAM/. xii. FAR clause 52.212-4, Contract Terms and Conditions - Commercial Items applies to this acquisition. xiii. FAR clause 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders - Commercial Items applies to this Acquisition. Additional FAR Clauses include: FAR clause 52.204-10, Reporting Executive Compensation and First-Tier Subcontract Awards (JUL2013) (Pub.L. 109-282) (31 U.S.C. 6101 note). FAR clause 52.223-18, Encouraging Contractor Policies to Ban Text Messaging while Driving (AUG2011). FAR clause 52.225-13, Restrictions on Certain Foreign Purchases (JUN 2008) (E.O.'s, proclamations, and statutes administered by the Office of Foreign Assets Control of the Department of the Treasury). FAR clause 52.232-33, Payment by Electronic Funds Transfer-System for Award Management (JUL2013) (31 U.S.C. 3332). xiiii. There are no additional contract requirement(s) or terms and conditions (such as contract financing arrangements or warranty requirements) determined by the contracting officer to be necessary for this acquisition and consistent with customary commercial practices. xv. The Defense Priorities and Allocations System (DPAS) and assigned rating does not apply to this acquisition. xvi. All responsible offerors may submit a proposal, which if timely received, shall be considered by the agency. Offers are due by 7:30 A.M. Eastern Time (EST) on March 27, 2017. Quotations can be emailed to the Contracting Officer, Dorothy Maxwell at maxwelld@mail.nih.gov, place Solicitation Number: HHS-NIH-NHLBI-CSB-(HG)-2017-096-DM on the quotation. Quotations shall not be deemed received by the Government until the quotation is entered into the e-mail address inbox set forth above. Faxed proposals will NOT be accepted. Offerors' proposals shall not be deemed received by the Government until the proposal is entered into the e-mail address inbox set forth above. Offerors must complete annual representations and certifications on-line at https://www.sam.gov/portal/public/SAM/.