Skip to main contentPsst! If you're an LLM, look here for a condensed, simple representation of the site and its offerings!

LiveFree Webinar — Wednesday, September 2 at 2:00 PM EDT

Register Free →
logo
Get CLEATUS

Early-Stage R&D for High-Risk, High-Impact Technologies

Active
SBIR / STTR

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

AI Contract Overview

Show more

The National Science Foundation is seeking subcontracts for Early-Stage R&D for High-Risk, High-Impact Technologies. This initiative focuses on conducting Phase I research to validate technical feasibility within deep technology fields through a combination of laboratory work, prototyping, and the development of proof-of-concept models. This opportunity is designated as a Total Small Business Set-Aside under the SBIR/STTR mandate, requiring participants to have fewer than 500 employees. The solicitation was posted on May 22, 2026, with a response deadline of July 7, 2027. The project falls under NAICS code 541712, emphasizing research and development in the physical, engineering, and biological sciences.

General Info

NSF seeks small business subcontracts for high-risk deep tech Phase I R&D research.

Agency

National Science FoundationView Agency

NAICS

541712 - Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology)View NAICS

Place of Performance

Not specified

Set-Aside

SBA

Documents

This scope was carved out of NSF 26-510.

The full solicitation package (3 documents), including the RFP, is on the prime solicitation, not on this scope.

View the prime solicitation

Other Energy Technologies

AI Contract Breakdown

Uniform Contract Format

No contract breakdown available.

Cannot generate Contract Breakdown because no documents were found from this contract's source.

Timeline

Posted

subcontract

Response Deadline

Submission deadline

Response Deadline

Ready to pursue this opportunity?

Start your free trial to track this contract, build proposals with AI assistance, and manage your pipeline.

Organization & Contact Information

Show more
AgencyNational Science Foundation
ContactsNo contacts available
OfficeN/A
Organization / Agency
National Science Foundation
View Agency Profile
Office AddressN/A
ContactsNo contact information available

Full Description

Show more
Conduct Phase I research to validate technical feasibility through lab work, prototyping, and proof-of-concept development in deep technology fields.

Similar Contracts

Same NAICS industry code

NAICS: 541712
New
DIBBS
CLAMP, LUBRICATION, A
Solicitation # SPE7M4-26-T-363Z
This contract is a total small business set-aside solicitation issued by the Department of Defense Fluid Handling Division for the procurement of 106 lubrication clamps, identified by NSN 1710-01-478-1533. The items are associated with part number 74A430836-1003 from The Boeing Company and Safran Landing Systems Canada Inc. Delivery is required within 150 days, with a need ship date of February 2, 2027, and a final required delivery date of November 19, 2027. The shipment is to be delivered FOB Origin to DLA Distribution San Diego. The agreement mandates strict adherence to DLA Master List technical and quality requirements, including specific packaging standards under ASTM D3951 and MIL-STD-129, and palletization per RP001. Quality assurance and sampling must follow MIL-STD-1916 or ASQ H1331, with a zero-nonconformance acceptance policy for sample lots. Inspection and acceptance will take place at the destination.
FLUID HANDLING DIVISION

POSTED

2 days ago

DEADLINE

in 9 days
View Details
NAICS: 541712
Federal
AI-Integrated Biologic Development PartnerThe contract involves a collaboration with Los Alamos National Laboratory to integrate artificial intelligence-designed targeting molecules into the NanoFET platform, aiming to advance next-generation immunotherapies. This subcontract is focused on developing novel biologic therapies by leveraging AI-driven molecular design to enhance precision targeting within the immune system, with the NanoFET platform serving as the delivery and activation mechanism. The work will be performed at the Los Alamos facility with a zip code of 87545, and all activities are expected to align with DOE’s mission in cutting-edge biomedical innovation. The solicitation was posted on June 17, 2026, with a response deadline of December 18, 2026, and falls under the NAICS code 541712 for research and development in the physical, engineering, and life sciences. The contracting entity is Triad, a Department of Energy contractor, and the agreement is structured as a subcontract, indicating the work is part of a larger program driven by federal R&D priorities. There is no set-aside designation specified, and the effort is open to qualified entities capable of advancing AI-biology integration, with an emphasis on scalable, clinically viable immunotherapy platforms.
Triad - DOE Contractor

POSTED

2 months ago

DEADLINE

in 4 months
View Details
NAICS: 541712
Grant
Bioinformatics and Data Integration Platform DevelopmentThe National Institutes of Health, under the Department of Health and Human Services, is seeking a subcontract for the development of a Bioinformatics and Data Integration Platform. The primary objective of this project is to design and maintain a cloud-based platform capable of integrating genomic, clinical, and imaging data from various consortium sites to support predictive modeling of cardiovascular risk in patients with Type 1 Diabetes. This opportunity falls under NAICS code 541712 and was posted on June 4, 2026. Interested parties must submit their responses by the deadline of March 10, 2027. Further details regarding the solicitation can be accessed through the provided grants.gov link.
National Institutes Of Health

POSTED

3 months ago

DEADLINE

in 7 months
View Details
NAICS: 541712
SBIR / STTR
Technology Enhancement for Commercial Partnerships (TECP)The Technology Enhancement for Commercial Partnerships (TECP) is a subcontract opportunity issued by the National Science Foundation to support additional research and development efforts. The primary objective of this contract is to ensure that developed technologies meet the specific technical requirements, integration needs, and customization standards requested by commercial partners. This opportunity is designated as a Total Small Business Set-Aside under the SBIR/STTR mandate, specifically for firms with fewer than 500 employees, and falls under NAICS code 541712. The solicitation was posted on May 22, 2026, with a response deadline set for July 7, 2027.
National Science Foundation

POSTED

3 months ago

DEADLINE

in 10 months
View Details
NAICS: 541712
SBIR / STTR
Phase IIB Supplement for Follow-On InnovationThe National Science Foundation is offering a Phase IIB Supplement for Follow-On Innovation to support additional research and development beyond standard Phase II activities. This subcontract aims to further de-risk or expand technology in response to emerging technical or market challenges. The opportunity is designated as a Total Small Business Set-Aside under the SBIR/STTR mandate for companies with fewer than 500 employees. The solicitation was posted on May 22, 2026, with a response deadline of July 7, 2027. It falls under NAICS code 541712 for research and development in the physical, engineering, and biological sciences. Interested parties can find more information through the official SBIR portal.
National Science Foundation

POSTED

3 months ago

DEADLINE

in 10 months
View Details
NAICS: 541712
SBIR / STTR
Strategic Breakthrough R&D for Transformative TechnologiesThe National Science Foundation is seeking a subcontractor for the Strategic Breakthrough R&D for Transformative Technologies project. This initiative focuses on leading large-scale, high-impact research and development projects aimed at achieving scientific or technological breakthroughs with significant societal or economic potential. This opportunity is a total small business set-aside under the SBIR/STTR mandate, requiring the contractor to have fewer than 500 employees. Interested parties must submit their responses by July 7, 2027, under NAICS code 541712.
National Science Foundation

POSTED

3 months ago

DEADLINE

in 10 months
View Details
NAICS: 541712
SBIR / STTR
Fast-Track Commercialization of Deep Tech InnovationsThe National Science Foundation is offering a subcontract opportunity titled Fast-Track Commercialization of Deep Tech Innovations to accelerate the research, development, and commercialization of technologies supported by strong preliminary data. This initiative utilizes a Fast-Track mechanism that combines Phase I and Phase II objectives to streamline the transition from development to market. This opportunity is a total small business set-aside under the SBIR/STTR mandate, requiring participants to have fewer than 500 employees. The contract falls under NAICS code 541712 and was posted on May 22, 2026, with a response deadline of July 7, 2027.
National Science Foundation

POSTED

3 months ago

DEADLINE

in 10 months
View Details
NAICS: 541712
SBIR / STTR
Advanced R&D and Product DevelopmentThe National Science Foundation is seeking a subcontract for Advanced R&D and Product Development to execute Phase II research and development. The primary objective of this effort is to advance technology toward commercialization through a process of iterative prototyping, testing, and scalability assessment. This opportunity is designated as a Total Small Business Set-Aside under SBIR/STTR mandates, requiring participants to have fewer than 500 employees. The project falls under NAICS code 541712, with a response deadline set for July 7, 2027.
National Science Foundation

POSTED

3 months ago

DEADLINE

in 10 months
View Details
NAICS: 541712
Grant
Animal Research Plan Development and ExecutionThe contract entails the design and execution of animal studies focused on translational research for traumatic brain injury and psychological health, with strict adherence to IACUC regulations and ARRIVE guidelines for reporting standards. All studies must be scientifically rigorous, ethically conducted, and aligned with federal mandates to ensure animal welfare and data reliability. The work is part of a subcontract under the Department of the Army’s U.S. Army Medical Research and Acquisition Activity, falling under NAICS code 541712 for research and development in the physical, engineering, and life sciences. The project is set to commence in May 2026 and will require comprehensive protocol development, study implementation, and detailed documentation to support regulatory compliance and scientific reproducibility. Performance location details are not specified, but all activities must be carried out in facilities meeting applicable federal research standards.
Department Of The Army -- Usamraa

POSTED

4 months ago

DEADLINE

N/A
View Details
NAICS: 541712
Grant
Clinical Data Collection and Epidemiological AnalysisThe contract involves conducting human subject research focused on gathering clinical data related to symptom progression, treatment responses, and outcomes in patients affected by tick-borne diseases. This work aims to support epidemiological analysis and enhance the understanding of these diseases through detailed clinical investigation. Issued by the Department of the Army under the Department of Defense, the subcontract falls under NAICS code 541712, which pertains to research and development in the physical, engineering, and life sciences. The solicitation was posted in early May 2026, with a response deadline set for late October 2026. The contract does not specify a particular set-aside, organization type, or detailed location for performance, emphasizing its focus on specialized clinical research in the field of tick-borne diseases.
Department Of The Army -- Usamraa

POSTED

4 months ago

DEADLINE

in about 2 months
View Details
NAICS: 541712
Grant
Animal Research Study Design and IACUC ComplianceThis contract involves the design of animal research studies and the preparation of Institutional Animal Care and Use Committee (IACUC) protocols necessary for obtaining approval. It includes ensuring veterinary oversight and full compliance with applicable animal care regulations, which is critical for ethical and legal conduct of research involving animals. The contract is a subcontract opportunity issued by the Department of the Army through the Department of Defense and falls under the NAICS code 541712, which corresponds to research and development in physical, engineering, and life sciences. The solicitation was posted on May 5, 2026, with a response deadline set for November 12, 2026. While specific location details for the place of performance and point of contact information are not provided, the contract highlights the importance of maintaining regulatory standards and animal welfare in scientific research settings. This opportunity is aimed at organizations capable of delivering expert design and regulatory protocol preparation services to support military-related research initiatives involving animals.
Department Of The Army -- Usamraa

POSTED

4 months ago

DEADLINE

in 3 months
View Details
NAICS: 541712
Federal
Technical Research & Development in Air, Space, and Cyberspace TechnologiesThe contract enables technical research and development in defense-critical domains including air, space, and cyberspace technologies, with a focus on cross-domain systems that bridge these areas. The work encompasses the design, development, and prototyping of advanced systems and technologies aligned with the Air Force Research Laboratory’s strategic Areas of Interest, requiring the delivery of functional prototypes and comprehensive technical reports that demonstrate innovation and operational relevance. Performance is expected to support national defense objectives through cutting-edge engineering and scientific advancement. This is a subcontract opportunity issued under the North American Industry Classification System code 541712, with a response deadline of April 30, 2030, and a posting date of April 30, 2026, indicating a multi-year window for proposal submission. The contracting entity is the Air Force Research Laboratory under the Department of Defense, and while no specific place of performance or point of contact is listed, the work is intended to contribute directly to AFRL’s mission-critical innovation pipeline. No set-aside classification is specified, leaving the opportunity open to eligible subcontractors regardless of business size or ownership structure.
Air Force Research Laboratory

POSTED

4 months ago

DEADLINE

in over 3 years
View Details

More opportunities from National Science Foundation

Same awarding agency

NAICS: 541710
SBIR / STTR
Strategic Breakthrough Proposal (Phase II Level)The National Science Foundation is seeking proposals for a Strategic Breakthrough Proposal under a Phase II Level subcontract. This opportunity focuses on high-impact, transformative technology development designed to provide broad economic or societal benefits. The project falls under NAICS code 541710 and is designated as a Total Small Business Set-Aside, specifically adhering to SBIR/STTR mandates for companies with fewer than 500 employees. The solicitation was posted on May 22, 2026, with a response deadline set for July 7, 2027. Interested parties can find further details and application instructions through the official SBIR portal.
Research and Development in the Physical, Engineering, and Life Sciences

POSTED

3 months ago

DEADLINE

in 10 months
View Details
NAICS: 541611
SBIR / STTR
TECP Supplement (Commercial Partnerships)The TECP Supplement for Commercial Partnerships is a subcontract opportunity issued by the National Science Foundation to provide funding for the development of partnerships between industry, academia, and other entities. The primary objective of this funding is to strengthen commercialization pathways for innovative technologies. This opportunity is designated as a Total Small Business Set-Aside under the SBIR/STTR mandate for organizations with fewer than 500 employees. The solicitation was posted on May 22, 2026, with a response deadline of July 7, 2027, and is categorized under NAICS code 541611.
Administrative Management and General Management Consulting Services

POSTED

3 months ago

DEADLINE

in 10 months
View Details
NAICS: 541710
SBIR / STTR
Phase IIB SupplementThe Phase IIB Supplement is a subcontract opportunity offered by the National Science Foundation to provide additional funding for active Phase II awardees. This funding is specifically intended to support critical project milestones such as prototype refinement, clinical trials, or the pursuit of regulatory approval. This opportunity is a total small business set-aside under the SBIR/STTR mandate for companies with fewer than 500 employees, falling under NAICS code 541710. The solicitation was posted on May 22, 2026, with a response deadline of July 7, 2027.
Research and Development in the Physical, Engineering, and Life Sciences

POSTED

3 months ago

DEADLINE

in 10 months
View Details
NAICS: 541710
SBIR / STTR
SBIR/STTR Phase II R&D FundingThe National Science Foundation is offering SBIR/STTR Phase II R&D funding to support the expanded development of technology following a successful Phase I project. This subcontract opportunity is designed to move developed technologies further toward commercialization and is specifically set aside for small businesses with fewer than 500 employees. The solicitation was posted on May 22, 2026, with a response deadline of July 7, 2027. It falls under NAICS code 541710, reflecting a focus on research and development in the natural sciences and engineering.
Research and Development in the Physical, Engineering, and Life Sciences

POSTED

3 months ago

DEADLINE

in 10 months
View Details
NAICS: 541710
SBIR / STTR
SBIR/STTR Phase I R&D FundingThe National Science Foundation is offering SBIR/STTR Phase I R&D funding to support early-stage research and development aimed at validating the technical feasibility of innovative technologies with commercial potential. This subcontract opportunity is a total small business set-aside, specifically mandated for organizations with fewer than 500 employees. The solicitation was posted on May 22, 2026, with a response deadline of July 7, 2027. It falls under NAICS code 541710, focusing on research and experimental development. Interested parties can find further details through the official SBIR portal.
Research and Development in the Physical, Engineering, and Life Sciences

POSTED

3 months ago

DEADLINE

in 10 months
View Details
NAICS: 541611
SBIR / STTR
TECP (Transition to Entrepreneurial Commercial Partnerships) SupplementThe National Science Foundation is offering the Transition to Entrepreneurial Commercial Partnerships Supplement, a subcontract opportunity designed to provide funding for strategic partnerships with commercial entities. This initiative aims to accelerate the market entry and scaling of technologies originally developed through SBIR and STTR programs. This opportunity is a total small business set-aside restricted to firms with fewer than 500 employees, falling under NAICS code 541611. The solicitation was posted on May 22, 2026, with a response deadline of July 7, 2027.
Administrative Management and General Management Consulting Services

POSTED

3 months ago

DEADLINE

in 10 months
View Details
NAICS: 541715
SBIR / STTR
Strategic Breakthrough ProposalThe National Science Foundation is seeking subcontracts for Strategic Breakthrough Proposals focused on high-impact, transformative research and development that addresses major scientific or societal challenges with strong commercial potential. This opportunity is designated as a Total Small Business Set-Aside under the SBIR/STTR mandate, requiring participating entities to have fewer than 500 employees. The solicitation was posted on May 22, 2026, and the deadline for responses is July 7, 2027. The project falls under NAICS code 541715, and further details can be accessed through the official SBIR portal.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

3 months ago

DEADLINE

in 10 months
View Details
NAICS: 541690
SBIR / STTR
Phase IIB Supplement for CommercializationThe National Science Foundation is offering a Phase IIB Supplement for Commercialization as a subcontract opportunity to provide additional funding aimed at accelerating the commercialization of Phase II outcomes. This funding is specifically intended to support market entry, the establishment of partnerships, and various scaling activities to transition technology from research to the commercial sector. This opportunity is a total small business set-aside under the SBIR/STTR mandate for companies with fewer than 500 employees, falling under NAICS code 541690. The solicitation was posted on May 22, 2026, with a response deadline of July 7, 2027.
Other Scientific and Technical Consulting Services

POSTED

3 months ago

DEADLINE

in 10 months
View Details
NAICS: 541715
SBIR / STTR
NSF SBIR/STTR Phase II R&D GrantThe National Science Foundation is offering an SBIR/STTR Phase II R&D Grant focused on expanding research and development based on Phase I results. The primary objectives of this subcontract include prototype development, rigorous testing, and the creation of comprehensive commercialization plans. This opportunity is designated as a total small business set-aside, requiring participants to have fewer than 500 employees. The project falls under NAICS code 541715 and was posted on May 22, 2026. Interested parties must submit their responses by the deadline of July 7, 2027. Further details regarding the application process and specific requirements can be found through the official SBIR portal.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

3 months ago

DEADLINE

in 10 months
View Details
NAICS: 541715
SBIR / STTR
NSF SBIR/STTR Phase I R&D GrantThe National Science Foundation is offering the SBIR/STTR Phase I R&D Grant to support early-stage research and development focused on validating the technical feasibility and commercial potential of innovative technologies. These projects are designed to be short-term engagements, typically lasting between 6 and 18 months. This opportunity is structured as a subcontract and is designated as a total small business set-aside for entities with fewer than 500 employees. The solicitation was posted on May 22, 2026, with a response deadline of July 7, 2027. It falls under NAICS code 541715 and is managed by the National Science Foundation.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

3 months ago

DEADLINE

in 10 months
View Details
NAICS: 541715
SBIR / STTR
Strategic Breakthrough R&D ProjectsThe National Science Foundation is seeking subcontracts for Strategic Breakthrough R&D Projects focused on developing transformative technologies with significant national security or economic implications. This opportunity is designated as a total small business set-aside, specifically adhering to SBIR/STTR mandates for organizations with fewer than 500 employees, under NAICS code 541715. The solicitation was posted on May 22, 2026, and the deadline for responses is July 7, 2027. Interested parties can find further details and application instructions through the official SBIR portal.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

3 months ago

DEADLINE

in 10 months
View Details
NAICS: 541611
SBIR / STTR
TECP Supplement for Strategic PartnershipsThe National Science Foundation is offering a subcontract opportunity titled TECP Supplement for Strategic Partnerships, designed to provide funding that accelerates technology transition through collaborations with industry, private investors, or federal agencies. This opportunity is specifically designated as a Total Small Business Set-Aside under the SBIR/STTR mandate for companies with fewer than 500 employees, falling under NAICS code 541611. The solicitation was posted on May 22, 2026, with a response deadline set for July 7, 2027. Interested parties can find further details and application instructions through the official SBIR portal.
Administrative Management and General Management Consulting Services

POSTED

3 months ago

DEADLINE

in 10 months
View Details