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Engineering Sleep for Cognitive Performance

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DPA26BZ03-DV012SBIR / STTR

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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The Defense Advanced Research Projects Agency is seeking innovative solutions to enhance cognitive performance and accelerate physiological recovery under conditions of severe sleep restriction, a known disruptor of critical brain functions such as glymphatic waste clearance and synaptic plasticity. This solicitation, titled Engineering Sleep for Cognitive Performance, is issued under the Small Business Innovation Research program as a Total Small Business Set-Aside, exclusively open to small businesses with fewer than 500 employees. The goal is to develop engineering approaches that can mitigate the degradation of essential neurophysiological processes caused by sleep deprivation, enabling sustained operational effectiveness in high-stress environments. Proposals must be submitted by July 22, 2026, and the opportunity was posted on June 3, 2026, through the SBIR/STTR portal. The project is funded by the Department of Defense and targets advanced technologies capable of replicating or enhancing the brain’s natural restorative mechanisms without relying on traditional sleep. There is no specified place of performance or point of contact listed, and the National Industrial Classification System code is not provided, suggesting flexibility in technical approach. The full details and submission guidelines are available through the official SBIR website link provided.

General Info

Small businesses develop engineering solutions to enhance cognition and recovery during severe sleep deprivation without traditional sleep.

Agency

Department of Defense → Defense Advanced Research Projects AgencyView Agency

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) View NAICS

Place of Performance

Not specified

Set-Aside

SBA

Documents

(0)

No documents available

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Timeline

PhaseSolicitation
Posted

Solicitation

Response Deadline

Submission deadline

Response Deadline

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Organization & Contact Information

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AgencyDepartment of Defense → Defense Advanced Research Projects Agency
ContactsNo contacts available
OfficeUS
Organization / Agency
Department of Defense → Defense Advanced Research Projects Agency
View Agency Profile
Office AddressUS
ContactsNo contact information available

Full Description

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The ability to sustain cognitive performance and accelerate physiological recovery is critical in demanding operational environments. Severe sleep restriction is known to degrade essential functions by disrupting the brain's natural restorative processes [1], including glymphatic waste clearance [2,3] and synaptic plasticity, which are tightly coupled to specific neurophysiological events during sleep [4].

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