Evotec Curated Chemical Library (Toxicology)

The Food and Drug Administration is forecasting a contract opportunity to secure external research support for developing a curated chemical library designed to evaluate assay performance in the High Priority Research Area of developmental neurotoxicity. This effort will involve the selection, preparation, and characterization of chemical compounds to serve as reference standards for testing and validating in vitro and in vivo screening systems used to assess neurodevelopmental toxicity. The work will be conducted under NAICS code 541990, which pertains to other scientific and technical consulting services, and is intended to enhance the agency’s capacity to identify and prioritize potential developmental neurotoxicants using robust, reproducible methodologies. The contract will require technical expertise in chemical library design, toxicology assay development, and data analysis, with the goal of producing a well-documented, high-quality collection of compounds that can be reliably used across multiple research platforms. The point of contact for program-related inquiries is the HFP Acquisition Liaison at hfpacquisitions@fda.hhs.gov, while the contracting officer position remains to be determined. The forecast was posted on May 25, 2026, and all performance activities will be conducted under the authority of the FDA without specified geographic restrictions, indicating the work may be carried out remotely or at the contractor’s facility. This initiative supports the FDA’s broader mission to safeguard public health by improving the scientific foundation for evaluating developmental risks associated with chemical exposures.