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This Solicitation opportunity was posted on May 20, 2009. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

Experimental infection and pathogenetic studies in chimpanzees

Closed
2009-N-11218Federal

Contract Overview

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General Info

Agency

N/A

Contract Value

$379,645

NAICS

541712 - Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology)

Place of Performance

TBD, USA

Set-Aside

NONE

Award Issued Date

Documents

0

No documents available

Documents will appear here when they are available.

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Timeline

PhaseClosed
Posted

Presolicitation

Response Deadline

Deadline has passed

Type Changed

Presolicitation → Solicitation

Submission Closed

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Organization & Contact Information

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AgencyN/A
Contacts2 people available
OfficeN/A
Organization / Agency
N/A
Office AddressN/A
Contacts
Betty B VannoySr. Contract Specialist
Arnette L. MayhewContract Specialist

Full Description

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The Centers for Disease Control and Prevention (CDC), Coordinating Center for Infectious Diseases (CCID), National Center for HIV/AIDS, Viral Hepatitis, STD and TB (NCHHSTP), Division of Viral Hepatitis (DVH) seeks to award one cost reimbursement type contract to an offeror to conduct three research studies: 1) Significance of CD4 cells for protective efficacy of HBV vaccine evaluated in chimpanzees; 2) Pathogenetic elements of experimental HEV genotype 3 infection in chimpanzees; 3) Serial blood and liver specimen collections during HCV infection in chimpanzees. The experiments will include infectious material inoculations, obtaining blood samples and liver biopsy specimens, and - for HEV infectivity studies - daily stool collection. The research animals will be housed at the vendor's facility accredited to house chimpanzees and fully equipped with qualified staff to perform approved experimentation and procedures. In addition to conducting the three research studies, the contractor will identify and provide, including the health records, the following chimpanzees: a) two hepatitis B immunized chimpanzees, which will have anti-HBs levels of at least 5,000 IU/mL; b) two specific pathogen (HEV) free chimpanzees, 10-14 kg of weight, seronegative for HAV, HBV, HCV and HEV; and c) two specific pathogen (HCV) pathogen free chimpanzees, 20 kg of weight or heavier, but not exceeding 35kg, seronegative for HAV and HEV. The period of performance for the prospective award will be thirty-six (36) months from the date of contract execution. This requirement is anticipated to be a full and open competition under North American Industrial Classification System (NAICS) Code 541712, Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology). Further instructions will follow in the Request for Proposal. A Request for Proposal will be made available on the Internet at http://www.fbo.gov on or about May 14, 2009. Requests for Proposals in hard copy form will not be available. Telephone requests will not be honored. Interested parties are responsible for checking the website regularly for release of the RFP and for other procurement-related documents.

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