This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. The solicitation number is NIH-NINDS-CSS-19-5381335 and the solicitation is issued as a request for quote (RFQ). This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures; FAR Subpart 13.5-Simplified Procedures for Certain Commercial Items; and FAR Part 12-Acquisition of Commercial Items, and is expected to exceed the simplified acquisition threshold. The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2019-03 thru July 12, 2019. The associated NAICS code 334516, "Analytical Laboratory Instrument Manufacturing" and the small busisess size standard 1000 employees. This requirement is full and open with no set-aside restrictions. Contract Type: A firm-fixed price type contract is contemplated for this requirement. Background Information and Objective: The NIH Mouse Imaging Facility (MIF) is a shared, intramural resource for preclinical animal imaging studies. The MIF provides the NIH intramural research community access to modern radiological imaging equipment optimized for rodents and other laboratory animals for noninvasive imaging studies. The MIF provides intellectual, technical and material support for NIH investigators. MIF imaging resources include: magnetic resonance imaging (MRI), micro-computed tomography (Micro-CT), high frequency ultrasound with photoacoustic imaging, bioluminescence and fluorescence imaging (optical imaging). The MIF is dedicated to providing state-of-the-art anatomical, functional and molecular medical imaging capabilities for animal models of human disease. The objective of this acquisition is to obtain a new high resolution ex-vivo micro CT scanner to replace the current one that is no longer supported by the manufacturer. Statement of Need and Purpose: The NIH Mouse Imaging Facility (MIF) needs a new high resolution ex-vivo Micro Computed Tomography (microCT) imager to replace the current scanner. The current scanner is no longer supported by the manufacturer. The scanner is required to capture extremely high resolution radiographic images of very small samples such as mouse teeth and bones, zebrafish and fruit flies. In the past five (5) years twelve (12) different NIH institutes have used the current ex-vivo microCT scanner and almost every institute has imaged tissue samples over its usage history. The ex-vivo microCT continues to be a MIF imaging resource in high demand. Salient Characteristics: The high resolution desktop microCT imaging system must include a minimum of the following characterstics: - Scanner shall Include a 16 megapixel 14-bit cooled CCD camera with a minimum three offset positions equaling three times the field of view. - Equipment shall produce reconstructed volumes up to 209 Megapixel (14450x14450 pixels) virtual slices through objects, more than 2600 such slices after a single scan. - Equipment must use phase-contrast enhancement to visualize object details as small as 0.35um (minimum pixel size). - Scanner must contain an acquisition geometry with ability to simultaneously adjust the sample distance and detector distance to the X-ray source automatically. This means that for most scans the sample can be in the Near position, increasing scan speed by 5X. For either the highest resolution scan or the largest samples, the detector moves into the Mid or Far positions. - Camera shall provide continuous magnification from 0.34um - 25um pixel sizes. - Scanner shall contain a field of View X-ray Detector for samples up to 75mm in diameter, 70 mm high. Detector has 5000 pixels horizontally and 3280 pixel vertically for large field of view in a single scan. The scanner shall have the capability for reconstruction arrays of 14,450'14,450 (200Mp+ in a single reconstructed image). - System shall have a maintenance-free X-ray source (20-100kV, 10W) with <5 micron spot size, with automatically variable spot size to conserve X-ray source lifetime. - Scanner shall have a 6-position automatic filter changer to adjust x-ray energy and energy filtering of X-ray source. - System shall have unrestricted reconstructed data size limit supported by multithreaded GPU-accelerated 3D-reconstruction and realistic visualization by surface and volume rendering. - Scanner shall include an integrated micropositioning stage with 5mm travel to achieve exact positioning of small objects in the middle of the scanning area. - Contractor shall provide a 16-position automatic sample changer to allow the adding, removing, and replacing of samples without interrupting a live scanning process. Automatic magnification adjustment and scanning protocol optimization available for individual samples. At the end of the scan the system sends an e-mail with a direct link to the scanning results, which can be opened across a network. - System shall provide thermal correction for reconstruction: Pixel Projection Shift Correction (PPSC) is an advanced reconstruction algorithm that corrects for any thermal changes of the X-ray source due to environmental changes. - Physical footprint not to exceed (1160 mm X 520 mm X 330 mm) for site location - Scanner must be fully shielded for radiation safety: <1 uSv/h at any point of instrument. - Contractor Shall include software supplied with unlimited site license with free updates for the life of the instrument. - Contractor shall provide unlimited phone, email, and online support for the SkyScan instrument for the life of the instrument. (Support for Dell workstation provided in the Dell warranty.) - Contractor shall provide onsite training on-site for up to 5 people. Please see the attached Purchase Description for more details. Other Applicable Provisions and Instructions 1) The provision at FAR clause 52.212-1, Instructions to Offerors - Commercial Items, applies to this acquisition and is attached. 2) The provision at FAR clause 52.212-2, Evaluation - Commercial Items, applies to this acquisition. (a) The Government will award a fixed price contract resulting from this solicitation to the lowest price technically acceptable (LPTA) offer. To be technically acceptable, the offer must satisfy the requirements outlined in the Purchase Description including salient characteristics, quantity, delivery and warranty requirements. (b) A written notice of award or acceptance of an offer, mailed or otherwise furnished to the successful offeror within the time for acceptance specified in the offer, shall result in a binding contract without further action by either party. Before the offer's specified expiration time, the Government may accept an offer (or part of an offer), whether or not there are negotiationsafter its receipt, unless a written notice of withdrawal is received before award. 3) The Offerors to include a completed copy of the provision at FAR clause 52.212-3, Offeror Representations and Certifications-Commercial Items, with its offer. 4) The FAR clause at 52.212-4, Contract Terms and Conditions - Commercial Items, applies to this acquisition and is incorporated by reference. 5) FAR clause at 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders-Commercial Items, applies to this acquisition. See attached document, "FAR 52.212-5 Applicable Clauses", for clauses applicable to this acquisition. 6) The provision of FAR Clause 52.204-24, is applicable to the solicitation and attached. Offerors are requested to complete and sign this attached provision and include with any submitted quotation. 7) FAR Clause 52.204-25, is applicable to the solicitation and attached. The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. Responses to this solicitation must include sufficient information to establish the interested parties' bona-fide capabilities of providing the product or service. The price quote shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s); product description; and any other information or factors that may be considered in the award decision. Such factors may include: past performance; special features required for effective program performance; trade-in considerations; probable life of the item selected as compared with that of a comparable item; warranty considerations; maintenance availability; and environmental and energy efficiency considerations. Respondents proposing on an equal product of the brand-name product specified in this announcement must provide, as part of their response: (a) product, catalog, model, and/or part number(s); (b) product description; (c) all relevant information and documentation that the item(s) offered meets the salient physical, functional, or performance characteristics as specified in the purchase description; quantity; estimated price or cost; shipping, handling, and/or installation charges; and delivery date after receipt of order. Please be advised that the National Institute on Neurological Disorders and Stroke (NI'NDS) is an Institute within the National Institutes of Health (NIH), which is a Federal agency. Your mass-market commercial and/or license agreement may include provisions that are customarily found in the commercial sector but which are not appropriate for a contract with a Federal agency. Specifically, NINDS considers any provision in your mass-market commercial and/or license agreement to be inappropriate and unenforceable that: (1) Contravenes a right granted NINDS under U.S. copyright law (e.g., fair use, right to archive, copying for interlibrary loan), (2) Violated the Federal Acquisition Regulation or other Federal law (e.g., Antideficiency Act, Principles of Federal Appropriations Law), (3) Departs from reasonable consumer expectations and was not disclosed by the Licensor prior to agreement, or (4) Violates fundamental public policy. NINDS shall assume that you are in agreement with the statements herein if you submit a quotation. In addition the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." There are no additional contract requirement(s) or terms and conditions applicable to this acquisition. All responses must be received by 11:00 A.M. EST on September 13, 2019 and reference solicitation number NIH-NINDS-CSS-19-5381335 Responses may be submitted electronically to danny.cohn@nih.gov. Fax responses will not be accepted.