HIVE Dragen Appliance Software

The HIVE Dragen Appliance Software contract involves the deployment of Illumina’s DRAGEN Bio-IT Platform, a high-performance genomics analysis system powered by field-programmable gate array technology that enables rapid processing of genomic data. This system accelerates key analytical steps such as BCL conversion, alignment, variant calling, and duplicate marking, reducing the time to analyze a 30x coverage human genome from overnight to approximately 25 minutes. It supports a wide range of sequencing data types including whole genomes, whole exomes, targeted panels, germline and somatic samples, and RNA sequencing, delivering high sensitivity and specificity in variant detection for clinical and research applications. The contract is forecasted under the NAICS code 541519 for other computer-related services and is associated with the Food and Drug Administration, with the point of contact for program inquiries listed as the CBER Acquisition Liaison at cberacquisitions@fda.hhs.gov. The contracting officer will be determined at a later date, and while no specific place of performance or set-aside details are provided, the procurement is aimed at enhancing the FDA’s capacity for advanced genomic data processing to support regulatory science and public health initiatives.