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In Vitro Pharmacological Testing Services

Active
International

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

General Info

Agency

Government of Canada → Department of HealthView Agency

NAICS

541380 - Testing Laboratories and ServicesView NAICS

Place of Performance

National Capital Region (NCR), CAN

Set-Aside

NONE

Documents

This scope was carved out of 1000273405.

The full solicitation package (12 documents), including the RFP, is on the prime solicitation, not on this scope.

View the prime solicitation

Request For Proposal (RFP) for Pharmacological testing of novel opioids, stimulants, and synthetic cannabinoids.

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Organization & Contact Information

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AgencyGovernment of Canada → Department of Health
ContactsNo contacts available
OfficeN/A
Organization / Agency
Government of Canada → Department of Health
View Agency Profile
Office AddressN/A
ContactsNo contact information available

Full Description

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Performs pharmacological testing of stimulant compounds and novel synthetic cannabinoids for prime contractors on Government of Canada research projects. Conducts in vitro methodologies, quantitative and statistical analyses, and validates experimental methodologies using cell lines and transgenes. Requires authorizations under the Controlled Drugs and Substances Act. Delivers validated experimental data and final summary reports.

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Request For Proposal (RFP) for Pharmacological testing of novel opioids, stimulants, and synthetic cannabinoids.
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Health Canada is seeking proposals under solicitation 1000273405 to conduct in vitro pharmacological testing of novel psychoactive substances to support regulatory science and risk assessments regarding the illegal drug supply. The procurement is divided into three separate streams: Stream 1 focuses on emerging opioids at the Mu Opioid Receptor, Stream 2 addresses novel synthetic cannabinoids targeting CB1 and CB2 receptors, and Stream 3 evaluates stimulant compounds, specifically dopamine and VMAT2 uptake. Bidders may submit proposals for a single stream, two streams, or all three, with the possibility of up to three contracts being awarded. The selected contractors will be responsible for acquiring reference standards and control samples, obtaining necessary licenses for controlled substances, and performing rigorous laboratory experiments including assay validation and pharmacodynamic testing. Key deliverables include the measurement of metrics such as Ki, Emax, and EC50, followed by statistical analysis and the submission of draft and final reports. Timelines for completion vary by stream, with some activities extending up to 17.5 months from the date of the contract award. Technical and financial offers must be submitted separately for each stream by the deadline of September 18, 2026.
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