Knockin of IRES_cre into the Rgs6 Gene

The National Institutes of Health (NIH), National Institute of Diabetes and Digestive Kidney Diseases (NIDDK) has a requirement to generate a Rgs11 promoter - driven Cre recombinase - expressing knock - in custom mouse model by Ogene Pty Ltd by other than full and open competition under the authority of FAR Part 13 Simplified Acquisitions. This acquisition was pursued on a sole source basis as a previous mouse model of a related gene, Rgs7, was successfully generated for our lab by Ozgene and now is working well in current experiments. For continuity of experimental design and compatibility and consistency of the mouse models, it is imperative that Ozgene generate the Rgs11 mutant mice. Vendors may identify in writing their interest and capability in response to this requirement or submit a proposal. This notice of intent is not a request for competitive proposals. However, all responses received before the closing date of this announcement will be considered by the Government. Information received will normally be considered solely for the purpose of determining whether to conduct a competitive procurement. All responsible sources may submit a quotation which, if timely received, shall be considered by the agency. Award to be made based on response offering the best value to the Government considering price and response time.