Multimodal microscope system for pharmaceutical particle analysis

The Food and Drug Administration is forecasting the acquisition of a high-resolution multimodal microscope system designed for advanced pharmaceutical particle analysis, specifically the mIRage-LS sub-micron IR system that combines Optical Photothermal Infrared spectroscopy with simultaneous Raman and fluorescence imaging. This integrated platform delivers sub-500nm spatial resolution, enabling detailed chemical composition mapping and morphological characterization of particles critical to drug development and quality control, all within a single analytical workflow. The system’s ability to concurrently collect infrared, Raman, and fluorescence data enhances the depth and accuracy of particle analysis, supporting regulatory science and formulation optimization efforts. The procurement is categorized under NAICS code 334516, indicating instrumentation for laboratory use, and is being managed by the FDA’s Center for Drug Evaluation and Research. The point of contact for program inquiries is the Cder Acquisition Liaison, reachable via cderacquisitions@fda.hhs.gov, while the contracting officer position remains to be determined. The opportunity was posted on May 25, 2026, and is accessible through the HHS Office of Small and Disadvantaged Business Utilization portal as a forecasted procurement, with no set-aside designation specified. No physical location for performance is defined beyond the agency’s general scope, indicating the system will likely be deployed at an FDA laboratory facility for research and compliance testing.