NIDA Center for Genetics Studies

The National Institute on Drug Abuse (NIDA) will solicit proposals from qualified organizations capable of maintaining and expanding the NIDA Center for Genetic Studies. In this effort, the contractor will be required to: (1) Receive de-identified clinical, diagnostic, pedigree structure, environmental exposure information and other phenotypic data along with blood samples or other biospecimens from funded grants and/or contracts supporting research on the genetics of addiction and addiction vulnerability; (2) Process these data and materials to create databases, serum, DNA, RNA, and cell lines; (3) Widely distribute all data and materials in the NIDA Human Genetics Initiative to qualified investigators in the scientific community in a cost effective manner; (4) Maintain storage of data and biomaterials; (5) As stipulated by NIDA staff, perform microarray typing on pre-existing and/or new de-identified biospecimens; (6) As stipulated by NIDA staff, perform high-throughput sequencing on pre-existing and/or new de-identified biospecimens for genomic and/or epigenomic analyses; (7) Support the creation of reprogrammed cellular derivatives, such as induced pluripotent stem cells (iPSCs) to facilitate the molecular and cellular study of brain development and addiction processes; (8) Create a cyberinfrastructure that enables interoperability and full access to distributed data, software and other information science resources as well as research summaries and outbound links for all addiction related studies available through the NIH database of Genotype and Phenotype (dbGaP) system; and (9) Faciliate NIDA genetic studies data (both genotype and phenotype) being uploaded into NIH databases such as BioSample, and the dbGaP systems. NIDA anticipates the award of one indefinite delivery, indefinite quantity (IDIQ), contract with both fixed price and cost reimbursement, non-severable and severable task orders. NIDA expects to award at least one task order to a single contractor at award. Future funding will be made through issuance of task orders and will be dependent on NIDA programmatic needs and the availibilty of funds. NIDA anticipates subcontracting opportunities under this project. Mandatory Qualifications: Prior to award, the offeror must: (1) Have or be able to obtain a Certificate of Confidentiality (http://grants.nih.gov/grants/policy/coc/) and waiver from the Veteran's Administration's (VA) Office of Research and Development (ORD) to store VA-supported biological samples (see: http://www.research.va.gov/programs/tissue_banking/Tissue-Banking-FAQ.pdf); (2) State in writing that it agrees to and is committed to processing, generating, and widely distributing high-quality data files, documentation, and biological materials (cell lines, DNA, and serum) in an efficient and cost-effective manner for use in genetic analyses by qualified investigators in the scientific community; (3) Provide information on ability to obtain CLIA certification for microarray platforms (i.e., smokescreen) (see: https://biorealmresearch.com/category/press-releases/); (4) Be a co-signatory of the Distribution Agreement developed by the National Institute on Drug Abuse (NIDA) http://www.drugabuse.gov/researchers/research-resources/genetics-research-resources/nida-distribution-agreement. The earliest NIDA will post the RFP is 15 days from today. You will be able to access the RFP through the FedBizOpps website (URL: http://www.fbo.gov) or through the NIDA website: (URL: http://www.nida.nih.gov/RFP/RFPList.html). All information required for the submission of a proposal is contained in or accessible through the RFP package. After NIDA issues the RFP, responses are due in NIDA's Contracting Office within 45 days. NIDA will consider proposals submitted by any responsible offeror. This advertisement does not commit the Government to award a contract. Note 26. Based upon market research, the Government is not using the policies contained in Part 12, Acquisition of Commercial Items, in its solicitation for the described supplies or services. However, you may identify to the Contracting Officer its interest and capability to satisfy the Government's requirement with a commercial item within 15 days of this notice.