NOI - DNA Sequencing of Bone Marrow Failure Syndro
Contract Overview
Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.
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The National Institutes of Health, Office of the Director, intends to award a non-competitive, firm-fixed-price purchase order for custom-designed ArcherDX VariantPlex Next-Generation Sequencing target-enrichment library preparation kits. This acquisition, conducted under solicitation 75N98027Q00027, is designated for the NHLBI Hematology Branch to support the screening of over 200 patient samples for aplastic anemia and bone marrow failure syndromes. The government intends to negotiate with Integrated DNA Technologies, Inc. as the sole owner and manufacturer of the proprietary ArcherDX VariantPlex Anchored Multiplex PCR chemistry, which is essential for maintaining scientific continuity and compatibility with existing bioinformatics pipelines and Illumina NovaSeq instruments. The requirement falls under NAICS code 325413 and is not set aside for small businesses. The kits must feature pre-amplification ligation of unique molecular barcodes to enable error-correcting sequencing and must be delivered to Bethesda, Maryland, within an estimated turnaround time of four to six weeks after receipt of order. Proposals must be submitted by November 2, 2026, and include a Unique Entity Identifier, Taxpayer Identification Number, and business size certification. Award evaluation may consider technical capability, past performance, and lifecycle expectations, while all invoicing must be processed through the Invoicing Processing Platform using a three-way match.
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(ii) The solicitation number is 75N98027Q00027. This solicitation is issued as a Notice of Intent (NOI) for a non-competitive combined synopsis/solicitation to award a contract or purchase order without providing for full and open competition (including brand-name, if applicable).
This acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Products or Commercial Services, and is not expected to exceed the simplified acquisition threshold. Additional authority includes 41 U.S.C. 1901 and FAR 6.302-3(a)(2)(ii).
The National Institutes of Health (NIH), Office of the Director, Office of Acquisitions, intends to negotiate and award a firm-fixed-price purchase order on a non-competitive basis to Integrated DNA Technologies, Inc. (IDT), 1710 Commercial Park, Coralville, IA 52241, for custom-designed ArcherDX VariantPlex Next-Generation Sequencing (NGS) target-enrichment library preparation kits. Integrated DNA Technologies, Inc. is the sole owner, manufacturer, and distributor of the proprietary ArcherDX VariantPlex Anchored Multiplex PCR (AMP) chemistry, which has been utilized by the NHLBI Hematology Branch since 2019 to perform error-correcting sequencing (ECS) and is required to maintain scientific continuity, prevent technical batch effects across longitudinal patient cohorts, and ensure compatibility with the laboratory¿s established Archer Analysis bioinformatics pipeline. All responsible sources may submit a capability statement, proposal, or quotation, which shall be considered by the agency.
(iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2026-01, effective 03/13/2026.
(iv) The associated NAICS code is 325413 (In-Vitro Diagnostic Substance Manufacturing) and the small business size standard is 1,250 employees. This requirement is not set aside for small business.
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