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Nonclinical Mouse PK/PD Study Execution

Active

Federal

Response Deadline08/24/2026, 12:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

AI Contract Overview

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The contract requires the execution of in vivo pharmacokinetic and pharmacodynamic studies in mice to evaluate novel NNMT inhibitors, encompassing all aspects of animal dosing, blood and tissue sample collection, and proper handling of biological specimens to ensure data integrity. The work must adhere to standardized protocols for assessing drug absorption, distribution, metabolism, and excretion alongside downstream biomarker analysis to determine pharmacodynamic effects in live animal models. This subcontract is issued under the NAICS code 541620, indicating it pertains to scientific research and development services, and is solicited by the National Institutes of Health through the Department of Health and Human Services. The opportunity was posted on August 8, 2026, with a response deadline of August 24, 2026, and performance is expected to be conducted under the oversight of the NIH without specified geographic limitations. The scope demands expertise in preclinical mouse studies, robust sample processing, and precise pharmacological data generation to support further drug development decisions.

General Info

Conduct in vivo mouse PK/PD studies on NNMT inhibitors with strict sample handling and NIH oversight.

Agency

Department Of Health And Human Services → National Institutes Of Health OlaoView Agency

NAICS

541620 - Environmental Consulting ServicesView NAICS

Place of Performance

MD

Set-Aside

NONE

Documents

(0)

No documents available

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Timeline

PostedAug 8

subcontract

Response DeadlineAug 24

Submission deadline

Response Deadline

08/24/2026, 12:00:00 PM UTCin 16 days

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health Olao

ContactsNo contacts available

OfficeN/A

Organization / Agency

Department Of Health And Human Services → National Institutes Of Health Olao

View Agency Profile

Office AddressN/A

ContactsNo contact information available

Full Description

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Conduct in vivo pharmacokinetic and pharmacodynamic studies in mice, including animal dosing, blood/tissue sampling, and biological sample handling for NNMT inhibitors.

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