This Pre-Solicitation opportunity from Department Of Health And Human Services was posted on June 10, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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PAXGENE Ribonucleic acid extraction, quality control and aliquoting services

Closed

75N98026Q00583Federal

Submission Closed06/20/2026, 01:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541714

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AI Contract Overview

The contract seeks comprehensive PAXgene ribonucleic acid extraction, quantitation, normalization, Agilent quality control, and aliquoting services for 122 PAXgene tube units sourced from 50 clinical participants to support NIDDK clinical research and downstream transcriptomic analysis. The contractor must perform high-quality RNA extraction using validated protocols, followed by DNase treatment to eliminate genomic DNA contamination, precise quantitation and normalization to ensure consistent sample concentrations, and rigorous quality assessment via Agilent instrumentation to confirm sample integrity and suitability for gene expression profiling. Each sample may be divided into up to twenty-one aliquots, with all materials maintained under secure frozen storage conditions throughout processing, storage, and shipment, which must be conducted on dry ice. The contractor is required to inspect all specimens upon receipt, verify their integrity through visual and temperature monitoring checks, and immediately report any damaged, compromised, or nonconforming samples to NIDDK for replacement. Complete documentation and traceability are mandatory, including detailed logging of every processing step and sample status, alongside the provision of certificates of analysis, donor documentation, and chain-of-custody records upon delivery. Order status updates and real-time shipment tracking information must be provided to designated NIDDK personnel throughout the performance period. All activities must occur at the designated location in Bethesda, Maryland, with no set-aside provisions applied and the NAICS code 541714 governing the procurement. The solicitation, numbered 75N98026Q00583, is a presolicitation issued by the National Institutes of Health under the Department of Health and Human Services, with proposals due by June 20, 2026, though no estimated contract value or pricing details are included in the documentation.

General Info

Procure specialized RNA extraction, quality control, storage, and shipment for NIDDK clinical research in Maryland.

Agency

Department Of Health And Human Services → National Institutes Of Health OlaoView Agency

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)View NAICS

Place of Performance

MD, 20892, USA

Set-Aside

NONE

Documents

(1)

Requirements for PAXgene RNA Extraction and Aliquoting Services

DOCX•sow

AI Contract Breakdown

Uniform Contract Format

Timeline

PhaseClosed

PostedJun 10

Presolicitation

Response DeadlineJun 20

Deadline has passed

Submission Closed

06/20/2026, 01:00:00 PM UTC

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Organization & Contact Information

AgencyDepartment Of Health And Human Services → National Institutes Of Health Olao

Contacts1 person available

OfficeBETHESDA, MD, 20892, USA

Organization / Agency

Department Of Health And Human Services → National Institutes Of Health Olao

View Agency Profile

Office AddressBETHESDA, MD, 20892, USA

Contacts

John Burton

contact@example.gov

Full Description

Requirements

3.0 OBJECTIVE

The objective of this requirement is to procure PAXgene ribonucleic acid extraction, quantitation, normalization, Agilent quality control, and aliquoting services for samples collected from 50 clinical participants in support of ongoing NIDDK clinical protocol research and downstream transcriptomic analysis.

These services are necessary to support research involving gene expression profiling, molecular characterization of biospecimens, identification of disease mechanisms, and evaluation of potential therapeutic targets through transcriptomic analysis.

4.0 CONTRACTOR REQUIREMENTS

The contractor shall provide PAXgene ribonucleic acid extraction and aliquoting services for 122 PAXgene tube units collected from 50 clinical participants. Services shall include ribonucleic acid extraction, quantitation, normalization, Agilent quality control testing, aliquoting, frozen storage, and shipment on dry ice.

The contractor shall perform high-quality ribonucleic acid extraction from PAXgene tubes using validated protocols and established laboratory procedures.

The contractor shall perform ribonucleic acid quantitation and normalization to ensure consistent sample concentrations suitable for downstream transcriptomic analysis.

The contractor shall perform deoxyribonuclease (DNase) treatment to remove genomic deoxyribonucleic acid contaminants and ensure clean ribonucleic acid preparations.

The contractor shall perform ribonucleic acid integrity and quality assessments using Agilent instrumentation to verify sample suitability for downstream transcriptomic analysis.

The contractor shall aliquot up to twenty-one (21) aliquots per sample and provide secure frozen storage conditions to prevent sample degradation prior to shipment.

The contractor shall maintain complete documentation and traceability records, including logging of processing steps and sample status throughout all stages of handling and processing.

Quality Control

Upon receipt, all specimens shall meet the contractor’s established quality control acceptance criteria for processing.

The contractor shall inspect all specimens upon receipt and immediately notify NIDDK of any compromised, damaged, or nonconforming specimens requiring replacement.

The contractor shall verify specimen integrity upon delivery through visual inspection and temperature monitoring procedures.

Repository Management

The contractor shall provide certificates of analysis and donor documentation for each specimen, as applicable.

The contractor shall provide shipping documentation and chain-of-custody records to NIDDK upon delivery.

The contractor shall ensure specimens are maintained and stored under appropriate frozen conditions throughout handling, storage, and shipment activities.

The contractor shall provide order status updates and shipment tracking information to designated NIDDK personnel throughout the period of performance.