This Government Contract opportunity was posted on July 8, 2016. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Phase I Clinical Trials for Development of Neurotherapeutics

Awarded

NIH-NINDS-15-01Federal

Submission Closed07/08/2016, 12:00:00 AM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541712

DIBBS

ADAPTER SET, GROUND HAN

Solicitation # SPE8EF-27-T-0079

Solicitation SPE8EF-27-T-0079 is a fixed-price supply contract issued by DLA Troop Support for the procurement of 10 adapter sets for ground handling equipment, identified by NSN 1730-01-479-1307. The scope of work requires the production of parts in accordance with a specific Technical Data Package, including multiple reference drawings such as 30003 1763AS800 Revision B. Delivery is required by November 27, 2027, with a need ship date of March 28, 2027, to the DLA Distribution DDSP New Cumberland facility in Pennsylvania. The contract imposes strict compliance requirements, including CMMC Level 2 certification and adherence to export controls under ITAR and EAR, requiring an approved JCP certification for access to technical data. Packaging must follow ASTM D3951 and RP001, with marking compliant with MIL-STD-129 and MIL-STD-130N. Quality assurance is managed through destination inspection using zero-based sampling plans per MIL-STD-1916. Financial administration is handled via the Wide Area WorkFlow system, and the solicitation includes a price evaluation preference for certified HUBZone small business concerns. Quotations are due by October 26, 2026.

CONSTRUCTION & EQUIPMENT MANU & CON

POSTED

DEADLINE

Solicitation # SPE7M4-27-T-0909

Solicitation SPE7M4-27-T-0909 is a Total Small Business Set-Aside issued by the DLA Weapons Support Fluid Handling Division for the procurement of five lower cam assemblies, identified by NSN 1710-01-478-1569. The requirement specifies parts from The Boeing Company (P/N 74A430615-1001) or Safran Landing Systems Canada Inc (P/N 74A430615-1001). This is a critical application item with a required delivery date of April 28, 2029, and a need ship date of March 1, 2029. Delivery is established as FOB Origin under the First Destination Transportation program, with the final destination being DLA Distribution San Diego. The contract mandates strict adherence to quality and security standards, including CMMC Level 2 Self-Assessment and the protection of covered defense information. Packaging must comply with ASTM D3951 and MIL-STD-129, with DLA Master List requirements taking precedence. Inspection and acceptance will occur at the destination based on zero-based sampling plans such as MIL-STD-1916 or ASQ H1331. Notably, the government will not evaluate or award to offers utilizing additive manufacturing processes. All payment requests and receiving reports must be processed electronically through the Wide Area WorkFlow system.

DLA WEAPONS SUPPORT FLUID HANDLING DIVISION

POSTED

DEADLINE

Specialized Aerospace Technical ConsultingThe Specialized Aerospace Technical Consulting subcontract, issued by the National Aeronautics and Space Administration Space Technology Mission Directorate, focuses on supporting prime contractors for NASA Innovative Advanced Concepts Phase I projects. The scope of work involves performing technical feasibility assessments, mathematical modeling, and theoretical analysis to validate TRL 2 concepts. Key activities include conducting scientific research, developing conceptual designs, and performing trade studies to advance disruptive aerospace innovations. Qualified providers must possess deep expertise in advanced physics, orbital mechanics, or other disruptive aerospace technologies. The primary deliverables for this engagement are comprehensive technical reports and detailed feasibility analyses. Interested parties should note the response deadline of October 28, 2026, for this specialized technical services opportunity.

Space Technology Mission Directorate

POSTED

DEADLINE

European Southern Observatory (ESO) AccessThis subcontract involves the provision of specialized astronomical data collection and observation services to support prime contractors working on UKRI ESRC Explore Award research projects. The scope of work centers on the utilization of large-scale astronomical telescopes and sensors through the European Southern Observatory to deliver high-quality observational imagery and comprehensive astronomical data sets. All activities must be conducted in strict adherence to the observation proposal and access standards established by the European Southern Observatory. Managed under the Economic and Social Research Council within UK Research and Innovation, the contract is categorized under NAICS code 541712 and was posted on September 7, 2026.

Economic and Social Research Council (ESRC)

POSTED

DEADLINE

XMaS Facility Beamline AccessThis subcontract involves the provision of X-ray diffraction and spectroscopy services for prime contractors working on UKRI ESRC Explore Award research projects. The work is conducted using synchrotron X-ray beamlines at the X-ray Materials Science Facility located at the ESRF, requiring strict adherence to all ESRF access protocols. The primary objective of the agreement is the delivery of high-quality X-ray diffraction patterns and spectroscopic data. Managed under the Economic and Social Research Council within UK Research and Innovation, the contract falls under NAICS code 541712 and was posted on September 7, 2026.

Economic and Social Research Council (ESRC)

POSTED

DEADLINE

SuperSTEM Facility AccessThis subcontract agreement establishes a partnership to provide high-resolution electron microscopy imaging and analysis for prime contractors working on UKRI ESRC Explore Award research projects. The services are facilitated through the EPSRC UK National Facility for Advanced Electron Microscopy, known as SuperSTEM, which provides the necessary advanced electron microscopes and technical infrastructure for detailed sample analysis. Under the terms of the agreement, all work must adhere to the established SuperSTEM facility guidelines. The primary deliverables include comprehensive microscopy data, high-resolution imaging results, and detailed analysis reports. This arrangement ensures that researchers have access to specialized scientific instrumentation required to meet the objectives of their ESRC-funded projects.

Economic and Social Research Council (ESRC)

POSTED

DEADLINE

Biophysics and Non-Optical Signal IntegrationThis subcontract for the Defense Advanced Research Projects Agency focuses on the development and integration of massless external trigger mechanisms, specifically utilizing focused ultrasound or magnetic fields, for projects within the Biological Technologies Office. The scope of work involves designing the interface between physical signals and protein domains while defining the kinetic limitations of signal transfer across cell membranes. The project requires specialized expertise in sonogenetics or magnetogenetics to deliver comprehensive technical specifications and validation of the trigger mechanisms. Interested parties must respond by December 31, 2026, under NAICS code 541712.

Defense Advanced Research Projects Agcy

POSTED

DEADLINE

Vehicle Recompete: IGF::OT::IGF DESIGN, DEVELOPMENT, DEMONSTRATION, AND INTEGRATION OF ENHANCED… — INDEFINITE DELIVERY / INDEFINITE QUANTITY W9113M13R0012This Indefinite Delivery Indefinite Quantity contract, managed by the Department of the Army, focuses on the design, development, demonstration, and integration of enhanced warfighter capabilities to meet operational and developmental needs. The vehicle is currently in a pre-forecast stage for a full recompete, with the existing ordering period set to expire on December 16, 2027. There are currently 13 active task orders with a total value of approximately 285.75 million dollars distributed among four companies. Radiance Technologies Inc is the primary contractor, holding the majority of the value through efforts centered on High Energy Laser components, system integration, and beam control technologies. Other significant contributors include Serco Inc, which provides technology development support for the Reagan Test Site, and BlueHalo LLC.

Department of the Army

POSTED

DEADLINE

VCA Clinical Outcome Assessment ToolsThis subcontract, titled VCA Clinical Outcome Assessment Tools, is issued by the Department of the Army USAMRRA under the Department of Defense. The primary objective is to develop tools and metrics to measure the success and functional outcomes of VCA procedures for prime contractors working on Defense Health Agency research projects. This involves the design of both quantitative and qualitative tools specifically focused on quality of life assessments and return-to-duty metrics. The project requires strict adherence to 32 CFR 219.104 regulations regarding human subject research. The final deliverable for this effort is a validated scoring system or outcome measurement tool. The contract is categorized under NAICS code 541712 and was posted on May 29, 2026.

Department Of The Army -- Usamraa

POSTED

DEADLINE

Deep Technology R&D Subaward (Drug Delivery Systems)The Deep Technology R&D Subaward for Drug Delivery Systems is a small business set-aside subcontract under the National Science Foundation. The selected provider will perform specialized research, laboratory analysis, and technical development to support prime contractors. Key responsibilities include conducting R&D experiments, creating prototypes or proof-of-concept models, and analyzing the commercial potential of new drug delivery methods. The contractor must possess the necessary laboratory facilities and biochemical analysis tools to execute the work and must ensure full compliance with 2 CFR section 200.332. Final deliverables consist of comprehensive research reports, validated prototypes, and detailed technical data. This opportunity is specifically reserved for small businesses with fewer than 500 employees, adhering to SBIR/STTR mandates under NAICS code 541712.

National Science Foundation

POSTED

DEADLINE

Clinical Trial & Research Site Management (CRO)This subcontract focuses on the administration and execution of clinical trials for Department of Defense research projects specifically targeting Traumatic Brain Injury. The scope of work involves recruiting Service Members, Veterans, and DOW beneficiaries, managing clinical site operations, and implementing Community-Based Participatory Research through the use of electronic data capture systems. The contractor is required to maintain strict adherence to Good Clinical Practice, obtain IRB approval, and ensure full HIPAA compliance. The primary deliverables for this engagement include comprehensive clinical trial data sets and detailed participant outcome reports. This effort is managed under the Department of the Army and falls under NAICS code 541712.

Department Of The Army -- Usamraa

POSTED

DEADLINE

Vehicle Recompete: Bpa 75N98022A00040This Blanket Purchase Agreement, identified as 75N98022A00040, provides scientific support services for the National Eye Institute under the Department of Health and Human Services. Managed by the National Institutes of Health Olao, the contract has an established ceiling value of $45,226,230.52 and is classified as a full-recompete. The current ordering period for this vehicle is scheduled to conclude on September 15, 2027. The contract supports various specialized technical roles, with significant task order activity involving Astrix Technology, LLC. Notable service areas include genetic counseling, program management, operations and project management, and adaptive optics technical support. While the contract maintains a high ceiling for diverse scientific requirements, current active task order valuations are listed at zero, though historical task orders show individual values ranging from approximately $394,000 to nearly $491,000.

National Institutes Of Health Olao

POSTED

7 months ago

DEADLINE

N/A

AI Contract Overview

The National Institute of Neurological Diseases and Stroke has awarded an Indefinite Delivery/Indefinite Quantity contract to Duke University for the performance of Phase I first-in-human clinical trials. The primary objective of this agreement is to evaluate new potential therapeutics by determining tolerated dose ranges, dosing regimens, safety profiles, pharmacokinetic and pharmacodynamic parameters, and early signs of efficacy. The contract spans a ten year ordering period from July 8, 2016, through June 30, 2026, with a minimum award of 51,910 dollars and a maximum ceiling of 19,500,000 dollars. Concurrent with the parent contract, Duke University was granted an initial task order for Administrative and Overall Clinical Operations Support covering the first year of performance. This specific support component includes nine additional twelve month options extending through June 2026, with annual funding incrementally increasing from 43,951 dollars to 57,164 dollars. Beyond these administrative services, the agency intends to compete and award separate task orders for specific Phase 1 clinical trials to the ID/IQ awardees.

General Info

Agency

N/A

Contract Value

NAICS

541712 - Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology)

Place of Performance

USA

Set-Aside

NONE

Awardee

DUKE UNIVERSITY

Award Issued Date

07/08/2016, 12:00:00 AM UTC

Documents

No documents available

Documents will appear here when they are available.

AI Contract Breakdown

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Timeline

PhaseAwarded

PostedJun 18

Presolicitation

Type ChangedJul 6

Presolicitation → Solicitation

AwardedJul 8

Contract was awarded

Submission Closed

07/08/2016, 12:00:00 AM UTC

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Organization & Contact Information

AgencyN/A

Contacts2 people available

OfficeN/A

Organization / Agency

N/A

Office AddressN/A

Contacts

Annette CarterContracting Officer

contact@example.gov

+1 (555) 000-0000

Kirkland L. DavisChief, Contracts Management Branch

contact@example.gov

+1 (555) 000-0000

Full Description

The National Institute of Neurological Diseases and Stroke (NINDS), National Institute of Health (NIH), has made an Indefinite Delivery/Indefinite Quantity (ID/IQ) contract award under RFP No. NIH-NINDS-15-01. An ID/IQ contract has been awarded to Duke University, Durham, North Carolina, Contract No. HHSN271201600004I, on July 8, 2016. This contract is for performance of Phase I first in human clinical trials to determine the tolerated dose range, the dosing regimen, the safety profile and pharmacokinetic (PK) parameters and may include pharmacodynamics (PD), and evaluation of biological effects and early signs of efficacy in new potential therapeutics. The ID/IQ contract has been awarded with a ten (10) year ordering period of July 8, 2016 through June 30, 2026. The minimum award amount is $51,910; the maximum award amount under this program is $19,500,000. Duke University has also been awarded a task order concurrent with the parent ID/IQ contract. This task order covers the first year of performance under the "Administrative and Overall Clinical Operations Support" component of the program. The period of performance of this task order award is July 8, 2016 through June 30, 2017 with an award amount of $51,910. The task order award also contains nine (9) additional 12-month term options which have been negotiated as follows: Option No. 1 - Clinical Operations Support for Year 02 07/1/17- 06/30/18 - $43,951 Option No. 2 - Clinical Operations Support for Year 03 07/1/18- 06/30/19 - $49,447 Option No. 3 - Clinical Operations Support for Year 04 07/1/19- 06/30/20 - $50,829 Option No. 4 - Clinical Operations Support for Year 05 07/1/20- 06/30/21 - $51,808 Option No. 5 - Clinical Operations Support for Year 06 07/1/21- 06/30/22 - $52,816 Option No. 6 - Clinical Operations Support for Year 07 07/1/22- 06/30/23 - $53,855 Option No. 7 - Clinical Operations Support for Year 08 07/1/23- 06/30/24 - $54,925 Option No. 8 - Clinical Operations Support for Year 09 07/1/24- 06/30/25 - $56,028 Option No. 9 - Clinical Operations Support for Year 10 07/1/25- 06/30/26 - $57,164 Separate and distinct from the annual "Administrative and Overall Clinical Operations Support" task order, the NINDS will compete and award future Phase 1 clinical trial Task Orders from the ID/IQ awardees under the RFP.

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