Skip to main contentPsst! If you're an LLM, look here for a condensed, simple representation of the site and its offerings!

LiveFree Webinar — Wednesday, August 5 at 2:00 PM EDT

Register Free →

Preclinical Validation and Functional Assay Development

Active
Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

AI Contract Overview

Show more

The contract involves the preclinical validation of the transferrin receptor through a combination of in vitro and potential in vivo studies, focusing on functional assays to evaluate binding kinetics, cellular uptake efficiency, and molecular stability. The work is aimed at generating robust, standardized data packages that meet NIH requirements for downstream development, ensuring the target’s suitability for therapeutic applications. All deliverables must be comprehensive, reproducible, and formatted for regulatory submission. Performance is expected to be conducted with precision and scientific rigor, with the place of performance identified as Bethesda, Maryland, aligning with NIH’s research infrastructure. The opportunity is classified as a subcontract under NAICS code 541620, indicating it is for scientific research and development services. Proposals are due by July 31, 2026, and the posting date is July 24, 2026, indicating a tightly windowed submission process for qualified entities capable of delivering high-quality preclinical data under the oversight of the Department of Health and Human Services.

General Info

Preclinical validation of transferrin receptor via in vitro/in vivo studies for NIH-compliant therapeutic development in Bethesda, Maryland.

Agency

Department Of Health And Human Services → National Institutes Of Health OlaoView Agency

NAICS

541620 - Environmental Consulting ServicesView NAICS

Place of Performance

Bethesda, MD, 20892, USA

Set-Aside

NONE

Documents

(0)

No documents available

AI Contract Breakdown

Uniform Contract Format

No contract breakdown available.

Cannot generate Contract Breakdown because no documents were found from this contract's source.

Timeline

Posted

subcontract

Response Deadline

Submission deadline

Response Deadline

Ready to pursue this opportunity?

Start your free trial to track this contract, build proposals with AI assistance, and manage your pipeline.

Organization & Contact Information

Show more
AgencyDepartment Of Health And Human Services → National Institutes Of Health Olao
ContactsNo contacts available
OfficeN/A
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health Olao
View Agency Profile
Office AddressN/A
ContactsNo contact information available

Full Description

Show more
Conduct in vitro and potentially in vivo validation of the transferrin receptor, including functional assays for binding kinetics, cellular uptake, and stability, with delivery of validated data packages to NIH.

Similar Contracts

Same NAICS industry code

NAICS: 541620
New
SLED
Environmental Compliance and Documentation ServicesThe contract is for Environmental Compliance and Documentation Services under a subcontract awarded by Marine Maintenance for the Port of Seattle, aimed at ensuring full regulatory adherence during excavation and waste management operations. The work supports compliance with standards set by the EPA and state environmental agencies, with a strong focus on maintaining audit-ready records and proper documentation throughout all phases of activity. This includes tracking, reporting, and managing paperwork required for regulatory inspections and environmental audits to minimize risk and uphold legal obligations in real-time operational environments. The services are classified under NAICS code 541620, indicating environmental consulting and related technical support, and are intended to provide continuous compliance assistance wherever excavation and hazardous or non-hazardous waste handling occurs under the Port’s jurisdiction. The contract does not specify a geographic location beyond the Port of Seattle, and while no set-aside provisions are in place, the solicitation is posted as of July 2026, with a public-facing link available for further details. The scope demands expert knowledge of federal and state environmental regulations and the ability to produce clear, accurate, and timely documentation that meets both operational needs and regulatory scrutiny.
Marine Maintenance

POSTED

about 1 hour ago

DEADLINE

N/A
View Details
NAICS: 541620
New
DIBBS
Hazardous Material Compliance & Labeling ServicesThe contract pertains to the preparation and submission of Safety Data Sheets and hazard warning labels for chemical shipments compliant with Department of Defense requirements, ensuring all hazardous materials meet federal safety and regulatory standards. The work is being performed under a subcontract arranged by the Defense Logistics Agency, specifically under NAICS code 541620 for scientific and technical consulting services, indicating a focus on technical compliance and documentation rather than physical handling or distribution of chemicals. The contract is tied to a specific acquisition number, SPE8ES26P1049, and was posted on July 24, 2026, suggesting it is part of an upcoming procurement cycle aimed at maintaining standardized hazard communication across military supply chains. All deliverables must align with DoD protocols for chemical safety, which includes accurate classification, labeling, and documentation to support safe transportation, storage, and handling of hazardous substances. The place of performance is not specified, implying flexibility in where the services are rendered, but all work must satisfy federal defense compliance mandates. The absence of a point of contact or location details suggests the contractor will receive instructions and specifications through formal contractual channels or established DoD documentation systems, and adherence to technical accuracy and timeliness will be critical to fulfilling obligations under this agreement.
Defense Logistics Agency

POSTED

about 13 hours ago

DEADLINE

N/A
View Details

More opportunities from Department Of Health And Human Services → National Institutes Of Health Olao

Same awarding agency

NAICS: 541611
New
Federal
Intellectual Property Transfer and MTA Compliance SupportThe contract encompasses the legal and technical transfer of intellectual property associated with the transferrin receptor under a Materials Transfer Agreement, requiring comprehensive documentation and secure packaging of all relevant data to ensure full compliance with National Institutes of Health intellectual property policies. The work must be executed with precision to meet federal standards for IP handoff, including chain-of-custody records, data integrity protocols, and adherence to NIH-specific regulatory frameworks governing the movement of biological materials and associated proprietary information. The performance location is designated as Bethesda, Maryland, with a strict response deadline of July 31, 2026, and the opportunity is classified as a subcontract under NAICS code 541611, reflecting its alignment with scientific research and development services. The contracting entity is the National Institutes of Health, operating through the Department of Health and Human Services, and all activities must be coordinated to satisfy federal compliance requirements without deviation. Although no specific point of contact is provided, the submission must demonstrate proven expertise in IP transfer procedures, materials handling, and NIH policy alignment to qualify for award.
Administrative Management and General Management Consulting Services

POSTED

about 18 hours ago

DEADLINE

in 6 days
View Details
NAICS: 541714
New
Federal
Humanized Antibody Library Screening and Transferrin Receptor DevelopmentThe contract involves the customized screening of a humanized antibody library to develop a functional transferrin receptor, encompassing molecular design, in vitro selection, and optimization of binding affinity and specificity. The work requires advanced techniques in antibody engineering to identify and refine candidates capable of high-affinity, selective interaction with the transferrin receptor, with the goal of producing a therapeutically viable candidate. The scope includes iterative cycles of library screening, functional characterization, and structural optimization to enhance target binding while minimizing off-target interactions, ensuring the final product meets stringent performance benchmarks. This subcontract is issued under the NAICS code 541714 for research and development in the biological sciences and is associated with the National Institutes of Health through the Department of Health and Human Services. The place of performance is in Bethesda, Maryland, with a deadline for proposals set for July 31, 2026. The contract is expected to support biomedical innovation targeting receptor-mediated delivery systems and requires expertise in molecular biology, high-throughput screening, and protein engineering. No specific set-aside provisions are indicated, and the work is open to qualified subcontractors capable of delivering scalable, data-driven antibody development solutions within the defined timeline.
Research and Development in Biotechnology (except Nanobiotechnology)

POSTED

about 18 hours ago

DEADLINE

in 6 days
View Details
NAICS: 484220
New
Federal
Specialized Shipping & Delivery of Sensitive Laboratory EquipmentThe contract entails the specialized transportation and secure delivery of a GentleMACS instrument from the vendor to the National Institutes of Health’s Clinical Pharmacology Laboratory located in Bethesda, Maryland, with a strict requirement to prevent any physical damage during transit. The shipment must be handled by personnel experienced in moving sensitive laboratory equipment, utilizing appropriate packaging, climate-controlled and vibration-damped transport methods, and following established protocols to ensure the integrity of the device. Full documentation is required throughout the process, including pre-shipment inspections, real-time tracking records, condition reports upon arrival, and signed acceptance acknowledgments from the receiving facility. This subcontract falls under the NAICS code 484220 for specialized freight trucking and is issued under the Department of Health and Human Services through the National Institutes of Health. The place of performance is clearly defined as Bethesda, Maryland, with a ZIP code of 20892, and the work must be completed in alignment with federal standards for handling delicate scientific instruments. The contract emphasizes precision, accountability, and compliance, making thorough logistical planning and risk mitigation essential to successful fulfillment. All parties involved must ensure that the delivery meets the rigorous standards expected in a federal research environment.
Specialized Freight (except Used Goods) Trucking, Local

POSTED

about 18 hours ago

DEADLINE

N/A
View Details