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This Combined Synopsis/Solicitation opportunity from Department Of Defense was posted on February 24, 2015. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

SPECIALIZED SUPPORT TO ADVANCE VACCINE DEVELOPMENT AGAINST DIARRHEAL DISEASES TO PROTECT THE WARFIGHTER

Closed
N44852_VACCINE_DEVEL_DIARRFederal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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about 9 hours ago

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NAICS: 561990
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Lifeguard Services at Patrick Space Force Base
Solicitation # FA252127QB013
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FA2521 45 Cons Pk

POSTED

about 13 hours ago

DEADLINE

in 6 days

General Info

NAICS

561990 - All Other Support Services

Place of Performance

NAMRU-6 AV. VENEZUELA CDRA. 36 BELLAVISTA CALLAO PERU, LIMA, DC, PER

Set-Aside

NONE

Documents

0

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Timeline

PhaseClosed
Posted

Combined Synopsis

Response Deadline

Deadline has passed

Submission Closed

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Organization & Contact Information

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AgencyDepartment Of Defense → Naval Medical Research Unit South
Contacts2 people available
OfficeWASHINGTON, DC, 20521-3230, USA
Office AddressWASHINGTON, DC, 20521-3230, USA
Contacts
Javier B. GilProcurement Supervisor
Genaro M VasquezPROCUREMENT AGENT

Full Description

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SCOPE OF WORK The U.S. NAVAL MEDICAL RESEARCH UNIT 6 (NAMRU-6) in Lima, Peru is requiring the service of an international organization, hereafter referred to as "the contractor", to provide advanced technical expertise to support vaccine development efforts in enteric diseases. The contractor must have a long-term collaborative agreement with NAMRU-6 and demonstrated track record conducting studies of diarrheal diseases in Peru as shown through strong publication records in this field as well as a long-term research infrastructure in Peru. Under the terms of this contract, the contractor will provide advanced scientific guidance during the execution of non-human primate trials conducted at NAMRU-6. Specifically, the contractor will assist in the implementation of state-of-the-art laboratory assays to measure vaccine-induced immune responses and define immune correlates of mucosal immunity in the context of vaccine studies for enteric diseases. The contractor will provide a full-time post-doctoral fellow who will be relocated to Lima, Peru during the duration of this contract to conduct studies at NAMRU-6. The fellow must have a strong research background in microbiology and immunology and demonstrated experience in the development and validation of immunological assays using multicolor flow cytometer, ELISA and immunohistochemistry among others. Due to the scope of this work, it is required that the post-doctoral fellow must have previous experience on research using animal models of human diseases. DELIVERABLES: - Amend IACUC vaccination/challenge protocols for ETEC, Shigella, and Champylobacter to longitudinally collect an expanded set of non-invasive and invasive tissue samples to evaluate correlates of protective immunity in non-human primates. - Develop and validate immunological assays to assess mucosal immunity in the non-human primate model including flow cytometry, ELISA and ELISPOT for NHP vaccine development studies. - Develop standard operating procedures (SOP) for the aforementioned assays. SOPs will be incorporated into bi-annual reports detailing progress in assay development to the contractor and NAMRU-6. - Execution of assays for all samples to support the aforementioned animal protocols at NAMRU-6. Support data analysis of the results - Lead the preparation of reports and scientific manuscripts for publication. PERIOD: This contract will be executed from March 17, 2015 to February 14, 2016 BUDGET: Estimated amount for the total period is $49,905.00

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