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This Combined Synopsis/Solicitation opportunity from Department Of Health And Human Services was posted on September 16, 2025. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

Tritium labeled ketamine metabolites (R-ketamine, S-ketamine and RR-HNK)

Closed
25-0004566Federal

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The contract involves the development and supply of tritium-labeled ketamine metabolites, specifically R-ketamine, S-ketamine, and RR-HNK, to support the NIH’s research into the pharmacology of these compounds, particularly in relation to the RR-HNK program. The project aims to produce key radiolabeled reagents—5 millicuries of each compound—to facilitate autoradiography studies that will enhance understanding of their mechanisms and biological pathways. The work is expected to be completed within five months from the award date, emphasizing a concise and targeted research timeline. This procurement is managed by the National Center for Advancing Translational Sciences (NCATS), part of the NIH, under the Department of Health and Human Services, with the solicitation posted in September 2025. The contract is open and not set aside for small businesses or specific categories, with a response deadline of September 22, 2025. The primary point of contact for inquiries is Brian Lind, reachable via email or phone. The project underscores NIH’s commitment to advancing translational science through innovative molecular research, aiming to improve understanding of key biological agents that could impact health and disease treatment.

General Info

NIH NCATS seeks tritium-labeled R-ketamine, S-ketamine, and RR-HNK, delivery in five months.

NAICS

541380 - Testing Laboratories and Services

Place of Performance

MD, 20850, USA

Set-Aside

NONE

Documents

1

Purchase Description for Radiolabeled Ketamine Metabolites

DOCX, High priority: read this first1 page · sow
High

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Timeline

PhaseClosed
Posted

Combined Synopsis

Response Deadline

Deadline has passed

Submission Closed

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health Ncats
Contacts1 person available
OfficeRockville, MD, 20850, USA
Office AddressRockville, MD, 20850, USA

Full Description

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The National Institutes of Health (NIH) is the nation's leading medical research agency and the primary Federal agency whose mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability, conducting, supporting and making medical discoveries that improve people's health and save lives. The National Center for Advancing Translational Sciences (NCATS) is a translational science center that prides itself on its tremendously productive pipeline and is innovative in a number of ways. One of these ways is the development of new Bioactive Small Molecules which can modulate key biological pathways in multiple disease indications. This bioactive small molecule project is one of the key projects that progresses the study of RR-HNK from a mechanistic and pharmacological perspective. The tritium labeled version of R-ketamine, S-ketamine and RR-HNK will provide key reagents for the study of the pharmacology of all 3 agents. General description: Labeled R and S Ketamine and 2R,6R-HNK Specific description: 5 mCi of R and S Ketamine and 2R,6R-HNK to conduct autoradiography work in support of our RR-HNK program. Period of Performance is within five (5) months from the award of contract.

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