Holly Knott

Holly Knott supports the National Cancer Institute’s procurement mission by managing complex acquisitions that enable cutting-edge cancer research and translational science. She handles contracts for scientific services, laboratory testing, and specialized technical support critical to advancing genomic analysis, precision medicine, and diagnostic innovation. Her work ensures that NCI’s research infrastructure remains equipped with high-performance tools and expert consulting services, aligning procurement strategies with the agency’s mission to accelerate breakthroughs in oncology. She typically oversees task orders and indefinite-delivery/indefinite-quantity contracts requiring technical rigor and compliance with federal research procurement standards. Knott maintains a strong working relationship with Roche Diagnostics Corporation, a key partner in providing advanced diagnostic platforms and laboratory systems essential to NCI’s research pipeline. Her procurement approach emphasizes long-term vendor collaboration with industry leaders who can deliver scalable, validated technologies under stringent regulatory and quality frameworks. While she engages with large, established contractors for specialized equipment and high-capacity services, she also integrates smaller firms capable of agile, niche technical support, ensuring a balanced and resilient supplier base. Her contracting patterns reflect a clear preference for open competition, with 72.7% of awards issued without set-aside designations. However, she consistently supports small business participation, allocating 27.3% of awards to total small business set-asides under FAR 19.5, demonstrating a deliberate effort to foster innovation from emerging vendors without compromising mission-critical requirements. Knott’s procurement focus centers on NAICS codes 541611 (management consulting), 611430 (professional training), and 541380 (testing laboratories), reflecting her emphasis on research support services, workforce development, and analytical capacity building. She frequently procures custom bioinformatics solutions, precision instrument maintenance, and laboratory certification services, underscoring her expertise in the intersection of biomedical research and technical service delivery.