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CYPROTEX US LLC

UEI: YNGLSAF57T14CAGE: 47UC6

CYPROTEX US LLC is a federal contractor, registered under UEI YNGLSAF57T14 and CAGE code 47UC6. It has been awarded $11,356,625 across 56 federal contracts. Primary work spans Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology), Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology), and Testing Laboratories and Services. Top awarding agencies include Environmental Protection Agency, Department Of The Interior, and Department Of Health And Human Services.

Contact Information

Registration and classification details

Registration

UEI Code

YNGLSAF57T14

CAGE Code

47UC6

Entity Structure

Corporate Entity (Not Tax Exempt)

Established

N/A

Business Classifications

202X

NAICS Codes

541380Testing Laboratories and Services(Primary)
541714Research and Development in Biotechnology (except Nanobiotechnology)
541715Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Federal Contracting Overview

Award totals, agency breakdown, NAICS distribution, and geographic footprint.

AI Capability Profile

CYPROTEX US LLC specializes in advanced toxicological research and analytical testing services for federal science and environmental agencies, with deep expertise in high-throughput toxicokinetics (HTTK), human neurite outgrowth assays, and network formation studies. The company delivers critical AD...

CYPROTEX US LLC specializes in advanced toxicological research and analytical testing services for federal science and environmental agencies, with deep expertise in high-throughput toxicokinetics (HTTK), human neurite outgrowth assays, and network formation studies. The company delivers critical ADME-Tox data using in vitro and computational models to evaluate chemical safety profiles, supporting regulatory decision-making under EPA and DOI mandates. Their technical capabilities encompass quantitative bioanalysis, chemical exposure modeling, and high-content screening assays that bridge pharmacokinetics with neurotoxicological endpoints, enabling predictive risk assessment without reliance on animal testing. This focus on next-generation toxicology methods positions them as a technical partner for agencies transitioning toward non-animal testing paradigms under the Tox21 and ToxCast initiatives. The contractor maintains a strong, sustained relationship with the Department of the Interior and the Environmental Protection Agency, delivering specialized toxicokinetic testing and chemical safety assays that inform environmental risk evaluations and regulatory policy. Their work for HHS supports bioanalytical validation for public health applications, demonstrating adaptability across federal science missions. Operating under NAICS 541715 and 541380, CYPROTEX US LLC is narrowly focused on physical and life sciences R&D and independent laboratory testing, serving the environmental health and chemical safety market with precision. Their niche lies in translating complex biological endpoints into actionable regulatory data using validated, high-throughput platforms. As a small business structured as a 2L entity based in Framingham, Massachusetts, CYPROTEX US LLC operates without federal certifications but maintains a targeted presence in the federal science contracting space, serving mission-critical research needs for agencies committed to modernizing toxicological assessment methodologies.

Key Performance Metrics

Awards Count

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Award Analytics & Distribution

Awards by Agency
Environmental Protection Agency$7.1M62.2%
Department Of The Interior$2.9M25.6%
Department Of Health And Human Services$1.4M12%
Other agencies (1 agencies, <0.5% each)$17.3K0.2%
Awards by NAICS
541712 - Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology)$7.0M62%
541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)$3.0M26.2%
541380 - Testing Laboratories and Services$1.2M10.8%
541990 - All Other Professional, Scientific, and Technical Services$104.5K0.9%
Others - Other NAICS codes (1 codes, <0.5% each)$9.5K0.1%
Awards by Agency Over Time
Export
Awards by Place of Performance

Open opportunities in CYPROTEX US LLC's top NAICS codes and agencies

NAICS: 541715
New
Federal
REQUEST FOR WHITE PAPERS BAA TOPIC: Topic 13. Biotechnology, “Controlling polymicrobial environments as a strategy for defeating harmful organisms while promoting the growth of beneficial organisms”
Solicitation # W912CG-26-S-BIOTECH
The U.S. Army Combat Capabilities Development Command Soldier Center is soliciting white papers under Broad Agency Announcement W911QY-25-R-0023 to advance biotechnological research focused on controlling polymicrobial environments to suppress harmful organisms while fostering beneficial ones, with specific emphasis on developing phage-based hygiene wipes to prevent urinary tract infections in female Warfighters. The effort aims to design, optimize, and test a cosmetic-grade formulation that maintains bacteriophage viability under extreme thermal conditions—particularly at 45°C for four weeks—while being compatible with natural cellulosic wipes, resealable packaging, and regulatory standards under the Modernization of Cosmetic Regulation Act. The proposed formulation must include a phage cocktail at a minimum titer of 1E8 PFU/ml, a neutral pH buffer, preservatives effective at pH 7–8, stabilizers like polyvinyl alcohol, and moisturizing agents, all without compromising phage activity. Up to three formulation iterations are expected, culminating in the delivery of 100 prototype wipe packs—50 with active phage and 50 without—for field-relevant testing. Submission begins with a white paper, limited to five pages, detailing the technical approach, management structure, relevant past performance, and a rough order of magnitude cost estimate covering a 12-month base period with two optional 12-month extensions. Only white papers submitted electronically by 31 August 2026, 5:00 p.m. EDT, to the designated email address will be considered eligible for further invitation to submit a full proposal. Evaluation will prioritize scientific merit, management capability, alignment with Army mission needs, and cost-effectiveness, with feedback provided to submitters. Selection of white papers does not guarantee funding or a contract award, as decisions are contingent on budget availability and program priorities. The government reserves the right to cancel the solicitation at any time without obligation. Award mechanisms may include a contract, grant, or cooperative agreement, though a contract is the intended outcome. Formal proposals will only be requested from top-scoring white papers, and no further communication with government technical personnel is permitted after submission of a full proposal.
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NAICS: 541990
New
Federal
J042--Fire Alarm System Inspection, Testing, Maintenance, and Certification Services at the Bedford VA Medical Center
Solicitation # 36C24126Q0613_0001
This contract, issued under solicitation number 36C24126Q0613 and amended via Amendment No. 0003 on July 27, 2026, is a Service-Disabled Veteran-Owned Small Business (SDVOSB) set-aside for Fire Alarm System Inspection, Testing, Maintenance, and Certification Services at the Bedford VA Medical Center and its affiliated Community-Based Outpatient Clinics in Massachusetts. The scope includes routine and emergency maintenance of fire alarm systems, fire suppression systems, kitchen suppression systems, and fire extinguishers across multiple locations, with services governed by VHA directives, NFPA 72, OSHA regulations, and The Joint Commission standards. The contract features a one-year base period beginning September 1, 2026, and four one-year option periods extending through August 31, 2031, with an additional six-month option for extension under FAR 52.217-8. The majority of fire extinguishers (712 of 719) operate on a 12-year life cycle with 6-year maintenance intervals, while three 10lb Carbon Dioxide and four 6Ltr Class K extinguishers follow a 5-year life cycle. No equipment upgrades are included; the contract is strictly limited to the replacement of existing components, with future upgrades like the EST3 to EST4 transition planned separately. Performance must comply with strict quality thresholds, including 99% response times for service requests and 100% accuracy in tracking unique device identifiers. Quarterly testing of 25% of devices and annual comprehensive system testing are required, with all activities documented and submitted for COR approval. The evaluation process is trade-off based, prioritizing technical capability and past performance before price, and is not LPTA. Offerors must be current in SAM with a valid UEI, self-certify as SDVOSB under NAICS 541990, and comply with FAR clauses including 52.209-9, 52.212-4, 52.217-8, and VA-specific clauses such as 852.219-73 and 852.204-70, which require identity verification and credentialing of personnel. Proposals must be submitted electronically by August 10, 2026, at noon Eastern Time via
241-NETWORK Contract Office 01 (36C241)

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NAICS: 541715
New
Federal
Airborne and Mobile Measurements to support NOAA ARL’s Research on Meteorology and Atmospheric Chemistry
Solicitation # 145022-26-0017
The contract solicits specialized airborne and mobile measurement services to support NOAA’s atmospheric research in key urban regions, including Washington DC/Baltimore and New York City, with additional focus on methane emissions characterization and boundary layer analysis using mobile ceilometers and drone-mounted analyzers. The contractor must provide fully equipped research aircraft, qualified flight crews, and operational support to conduct multiple research flights in compliance with FAA regulations, collecting high-quality meteorological, chemical, and navigational data that will be integrated with NOAA’s existing aircraft, satellite, and surface monitoring systems. Also required is the deployment of a mobile ceilometer for continuous planetary boundary layer height measurements and, when requested, FAA-compliant unmanned aircraft systems equipped with methane/ethane analyzers to quantify point source emissions. The effort includes analysis of mobile laboratory data collected during the 2026 SOCCER-AQ field campaign in Boston to identify and quantify urban emission sources, compare observations with emissions inventories and models, and produce peer-reviewed publications and conference presentations. Administrative coordination is a core component, with the prime contractor responsible for managing all subcontractors, overseeing financial and scheduling milestones, consolidating deliverables, and ensuring full compliance with contract terms through a firm fixed-price, all-or-none award. This is a small business set-aside under NAICS code 541715, with a performance period from September 1, 2026, to August 31, 2027, and payment terms of Net 30. All work is centered at NOAA’s Advanced Systems and Modeling Division in Riverdale Park, Maryland, with deliverables due by the end of the period of performance. Quotes must be submitted electronically by August 14, 2026, to the designated NOAA point of contact, and pricing must be provided in accordance with the SF18 form or company letterhead, including monthly and annual breakdowns. The government explicitly states it will not accept responsibility for non-receipt of quotes, and the awardee must confirm receipt. Wage determinations referenced under WD #2015-4265 and WD #2015-4187 apply, and administrative coordination responsibilities—including subcontract management, invoice processing, and final documentation—must be fulfilled by the prime contractor, though technical oversight of scientific tasks remains with NOAA and subcontractors. All contract provisions and clauses are accessible via acquisition.gov, and the solicitation does not require SAM representations that are not included in the official solicitation documents.
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NAICS: 541715
New
Federal
AJ11--(Late) Research Services - ID Neuroimaging Biomarkers for Brain Connectivity - BRONX | EDA: 9/25/26
Solicitation # 36C24E26R0022
The Department of Veterans Affairs, James J. Peters VA Medical Center, intends to award a sole-source contract to the New Jersey Institute of Technology (NJIT) for specialized research services focused on identifying neuroimaging biomarkers for brain connectivity, in support of an ongoing VA Merit Award. This action is justified under 41 U.S.C. §3304(a)(3) and FAR 6.103-3, as NJIT is the only entity with the unique, four-year-developed expertise, proprietary datasets, and validated methodologies essential to the research's continuity and scientific integrity. NJIT’s world-class proficiency in fNIRS-based brain connectivity research, backed by multiple peer-reviewed publications and sustained collaboration with VA investigators, cannot be replicated by other institutions, even those with fNIRS capabilities, due to the absence of proximity, shared data infrastructure, and proven technical proficiency. Any other source would introduce unacceptable delays or compromise the research outcomes. The solicitation number is 36C24E26R0022, with a posted date of August 5, 2026, and a deadline for capability statements of August 10, 2026, at 4:00 PM EST. While this is a notice of intent and not a competitive solicitation, any responsible source believing it can meet the requirement may submit a capability statement to Lynn Portman at lynn.portman@va.gov by the deadline; telephone responses are not accepted. The NAICS code is 541715, and the contracting office is located in Pittsburgh, PA, under the Rpo East (36C24E) organization. The government retains sole discretion to determine whether to proceed without competition, and no further opportunities for bid submission will be provided.
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NAICS: 541380
New
Federal
AN41--Research Services Neural Stem Cell Study for Spinal Cord Injury Pre-solicitation Notice with Intent to Sole Source
Solicitation # 36C24E26R0021
The Department of Veterans Affairs intends to award a sole source contract to Pharmaron (San Diego) Lab Services LLC for a one-year period to conduct an In vivo GLP study evaluating the safety, toxicity, and biodistribution of grafting a GMP H9 scNSC Working Cell Bank into athymic rats with spinal cord injury. The vendor will be responsible for the full execution of the study in strict compliance with FDA 21 CFR Part 58, including master protocol development, animal procurement, surgical and post-surgical care, animal perfusion, and generation of a final GLP-compliant report. The study requires rats to be injured, grafted with neural stem cells or controls, and sacrificed at 1, 3, or 9 months post-graft, with time-sensitive, hand-delivered stem cells transported on ice from the VA San Diego Medical Center, necessitating the vendor’s physical proximity to maintain scientific integrity. Pharmaron is designated as the only capable provider due to its unique integration of specialized expertise in neural stem cell therapies, proximity to the VA San Diego facility, and ability to deliver the entire suite of required GLP services under one framework, which no other vendor can match within the required timeline. This sole source procurement is justified under RFO 6.103-1, as no other source can satisfy the agency's critical needs to support regulatory submissions and clinical translation of therapies for spinal cord injury—a condition disproportionately impacting Veterans. The contract falls under NAICS code 541380 with a $19 million size standard and PSC AN41. Interested parties may submit inquiries via email to Ann Marie Stewart, Contracting Officer, until August 10, 2026, though the decision to pursue competition remains at the sole discretion of the VA.
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NAICS: 541715
New
Federal
ARMY OPEN SOLICITATION (AOS)
Solicitation # W9128Z-25-S-A002
The Army Open Solicitation (AOS), identified by solicitation number W9128Z-25-S-A002, is an indefinite, open solicitation issued by the U.S. Army Contracting Command – Aberdeen Proving Ground to rapidly acquire innovative commercial technologies and research-driven solutions across all Army mission areas. Designed to revitalizing the industrial base and enhancing Warfighter lethality, the solicitation leverages a flexible acquisition framework under multiple FAR, DFARS, and U.S. Code authorities, including Other Transactions, Commercial Solutions Opening, and prototype authorities. It supports both Active Capability Gap submissions and periodic Calls for Solutions, with responses evaluated based on technical merit, feasibility, schedule, price estimation, viability, and desirability using a trade-off approach rather than lowest price technically acceptable. The solicitation remains open indefinitely until canceled, with recent amendments through March 2026 expanding and clarifying Army Example Areas, refining submission procedures, and updating contracting information including Active Capability Gap mailboxes. All submissions must adhere to strict formatting requirements, including a single PDF submission not exceeding five pages or fifteen slides, with mandatory inclusion of an executive summary, company information, and rough order of magnitude cost and schedule estimates. Offerors must be registered in SAM, use WAWF for invoicing, and comply with stringent data storage and security requirements, including U.S.-only data hosting and full organizational conflict of interest disclosures. The solicitation encourages participation from small businesses, nontraditional defense contractors, and nonprofit research institutions, with specific certifications required through the Affirmation of Business Status Certification. Performance may occur at government facilities including Aberdeen Proving Ground and other CONUS/OCONUS locations as directed, with award timing anticipated in fiscal year 2026, and support expected through 2032. No fixed contract value is provided, as pricing is determined through competitive evaluation of commercial proposals under the solicitation's open-ended structure.
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NAICS: 541715
New
Federal
ATEC HQ 002 - Wide-Field Optical Data Fusion Modernization
Solicitation # ATEC_RIW26_002
The Army Contracting Command - Aberdeen Proving Ground, acting on behalf of the Army Test and Evaluation Command, has issued a Call for Solutions to advance Wide-Field Optical Data Fusion Modernization under solicitation number ATEC_RIW26_002. This initiative seeks innovative technical approaches to enhance the integration and processing of wide-field optical data, targeting improvements in operational effectiveness and system performance. Submissions must adhere to the guidance detailed in the CfS document and align with the overarching framework of the Army Open Solicitation W9128Z-25-S-A002. All communications regarding this solicitation must include the specific subject line format: “Call for Solution - [Your Company Name] - ATEC_RIW26_002” to ensure proper routing and processing. The deadline to submit questions is August 10, 2026, at 1500 EDT, and all proposals for Phase 1 are due by August 19, 2026, at 1500 EDT. The solicitation is managed by the Department of Defense through the ACC-APG office located in Aberdeen Proving Ground, Maryland, with primary point of contact Dennis Beauclair, Jr., and secondary contact Whitney J. Jackson. Proposers are directed to review both the Call for Solutions and the associated Army Open Solicitation posting for complete requirements, evaluation criteria, and submission protocols. Responses must be submitted through the designated SAM.gov portal linked in the official posting.
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NAICS: 541990
New
Federal
Macroeconomic Impacts of Highway Investment
Solicitation # 6913G626Q300045
The U.S. Department of Transportation’s Volpe National Transportation Systems Center is soliciting contractor support to perform macroeconomic modeling analyzing the impacts of highway investments in the United States, using the offeror’s proprietary model. This solicitation, identified as 6913G626Q300045, is conducted under FAR Part 12 for commercial items and FAR Part 13 simplified acquisition procedures, with the NAICS code 541990 and a small business size standard of $19.5 million. Offers must be submitted as firm fixed price quotations covering a base period with 20 optional line items, each requiring a specific dollar amount and a total sum. The deadline for submitting offers has been amended to August 13, 2026, at 3:00 PM Eastern Time, with all questions due by August 6, 2026, at 2:00 PM Eastern Time. Offers must be emailed to Karen Marino at the specified address, include the solicitation number, offeror’s Unique Entity Identifier, contact information, and a statement of agreement with all terms. Offerors must hold their prices firm for 60 days after the submission deadline, and awards will be made without discussions unless necessary, based on a best value determination considering price and other factors. The contract will incorporate FAR provisions 52.212-1, 52.212-2, and 52.212-4, along with additional clauses including evaluation of options and electronic submission of payment requests via TAR clause 1252.232-70. Contractors must maintain active SAM registration throughout the contract term.
6913G6 Volpe National Transportation System Cntr

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NAICS: 541380
New
Federal
Q301--Water Quality Testing - STC
Solicitation # 36C26326Q0971
The St. Cloud VA Health Care System in Minnesota is conducting market research to identify qualified contractors capable of providing accredited water quality testing services under NAICS code 541380, specifically requiring accreditation from the Minnesota Department of Health Environmental Laboratory Accreditation Program. This notice is not a solicitation and does not obligate the government to award a contract; it is solely for gathering information on available vendors, their capabilities, and socio-economic classifications, including whether they are SDVOSB, VOSB, Small Business, HUBZone, 8(a), Women-Owned, or other designated small business categories. Responses must include company information, SAM Unique Entity ID, a capability statement, and indication of any existing federal contracts such as GSA, FSS, or SEWP that could support procurement. All responses must be submitted via email to Contract Specialist John Milroy by 12:00 PM Central Time on August 12, 2026. The place of performance is St. Cloud, MN, with the coordinating office located in Saint Paul, MN. Responders are responsible for all costs associated with submitting information, and any proprietary data provided will be handled in accordance with applicable regulations. This action is strictly for planning and acquisition decision-making purposes under FAR 15.201(e), and submission does not guarantee inclusion on any future bidder list or receipt of a solicitation.
Network Contract Office 23 (36C263)

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