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Science Systems and Applications, Inc. MD 20706-6239 USA

UEI: SLED_BB349BC655EEDEB8

Science Systems and Applications, Inc. MD 20706-6239 USA is a federal contractor, registered under UEI SLED_BB349BC655EEDEB8. It has been awarded $343,293,380 in federal contracts. Primary work spans Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology). Top awarding agencies include National Aeronautics And Space Administration.

Contact Information

Registration and classification details

Registration

UEI Code

SLED_BB349BC655EEDEB8

Federal Contracting Overview

Award totals, agency breakdown, NAICS distribution, and geographic footprint.

AI Capability Profile

Science Systems and Applications, Inc. provides specialized research and development services, with technical expertise aligned with research and development in the physical, engineering, and life sciences. The company supports the NASA Langley Research Center, delivering technical solutions throug...

Key Performance Metrics

Awards Count

1

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Active

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Past period of performance

Total Awards

All time

Contracts

Prime · all time

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Grants

Prime · all time

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Award Analytics & Distribution

Awards by Agency

National Aeronautics And Space Administration$343.3M100%

Awards by NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)$343.3M100%

Awards by Agency Over Time

Awards by Place of Performance

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Open opportunities in Science Systems and Applications, Inc. MD 20706-6239 USA's top NAICS codes and agencies

Science, Technology & Innovation Data ProviderThis subcontract opportunity with the Government of Canada seeks a Science, Technology and Innovation Data Provider to support prime contractors on Public Services and Procurement Canada information product projects. The selected provider will be responsible for delivering technical datasets, innovation reports, patent data, technical specifications, and comprehensive R&D trend analysis. A critical requirement for this engagement is the provider's ability to enter into a Provider’s Master License Agreement. The project falls under NAICS code 541715 and will be performed within Canada. Interested parties must submit their responses by the deadline of March 31, 2027. This contract focuses on equipping prime contractors with the necessary technical data and innovation metrics to enhance the delivery of government information products.

Government of Canada / Gouvernement du Canada

POSTED

about 23 hours ago

DEADLINE

Highway Safety Research & AnalysisThis subcontract opportunity involves providing specialized research and analysis for prime contractors working on South Dakota Department of Transportation highway safety projects. The primary objective is to evaluate flagger operations to identify safety gaps and establish effectiveness metrics. The selected provider will utilize traffic simulation software to generate data-driven operational recommendations and deliver comprehensive research reports and data analysis summaries. The project is managed under the South Dakota State Government with a response deadline of December 17, 2026. Classified under NAICS code 541715, the contract focuses on technical research and analysis to enhance highway safety protocols within the state.

South Dakota State Government

POSTED

DEADLINE

in about 2 months

Computer Vision Algorithm Development for Aerial RefuelingThis subcontract for the U.S. Air Force focuses on the development and training of computer vision AI/ML models to support aerial refueling projects. The scope of work involves implementing object detection and tracking for aircraft and refueling booms, as well as utilizing spatial analysis to ensure precise alignment measurements. To execute these tasks, the contractor must utilize high-compute GPU clusters and advanced AI frameworks to train models based on aerial footage. The project is designated as a Total Small Business Set-Aside under NAICS code 541715, specifically targeting firms with fewer than 500 employees. Key deliverables include the final trained AI models, all associated source code, and comprehensive validation reports. Due to the nature of the defense work, strict adherence to DFARS 252.204-7012 and CMMC cybersecurity standards is mandatory. Responses are due by November 25, 2026.

POSTED

DEADLINE

Optical Design & Photonics ConsultingThis subcontract for Optical Design and Photonics Consulting supports U.S. Navy Office of Naval Research HUD projects by providing specialized optical engineering and design services for prime contractors. The scope of work involves utilizing Zemax or Code V software to design light-engine configurations, holographic optical elements, and waveguides. Key deliverables include feasibility analyses, simulation reports, and detailed optical design specifications. The opportunity is a total small business set-aside under NAICS code 541715, specifically mandated for SBIR/STTR entities with fewer than 500 employees. Contractors must adhere to NIST SP 800-171 cybersecurity requirements to ensure data protection. The response deadline for this requirement is November 25, 2026.

POSTED

DEADLINE

Information Assurance (IA) and Secure Data Exchange SpecialistThis subcontract opportunity for the U.S. Air Force focuses on research and development for Technical Data Package modernization projects. The selected specialist will develop technical frameworks for secure data exchange, conduct feasibility studies on Information Assurance protocols, and design secure transmission workflows. Key deliverables include secure exchange architecture designs and technical feasibility reports intended to support prime contractors. The contract is a Total Small Business Set-Aside under NAICS code 541715, specifically mandating SBIR/STTR compliance for firms with fewer than 500 employees. Due to the sensitive nature of the work, strict adherence to ITAR and EAR regulations is required, and all data handling systems must be CMMC-compliant. Responses are due by November 25, 2026.

POSTED

DEADLINE

Technical Research Subcontractor / ConsultantThis subcontract opportunity, issued by the U.S. Air Force under the Department of Defense, seeks a Technical Research Subcontractor or Consultant to support prime contractors on Department of War SBIR projects. The selected entity will be responsible for conducting specialized research and technical analysis to determine feasibility, developing methods to meet technical objectives, and delivering comprehensive data and research findings for final reports. The contract is a total small business set-aside under NAICS code 541715, requiring the subcontractor to have fewer than 500 employees. Key compliance requirements include adherence to CMMC standards for handling Controlled Unclassified Information and Federal Contract Information, the implementation of OCI mitigation plans, and strict following of protocols regarding Recombinant DNA or Human and Animal Subjects. Responses are due by November 25, 2026.

POSTED

DEADLINE

Senior Advisor Consultant (Biological Therapeutics SME)The Senior Advisor Consultant (Biological Therapeutics SME) is a small business set-aside subcontract under the Department of Health and Human Services, specifically within the Omas Strategic Buying Center for Professional Services. The selected consultant will provide subject matter expertise to prime contractors supporting NIH NINDS BPN-Biologics program projects. Primary responsibilities include leading biologic drug discovery for nervous system conditions, reviewing operations, and offering strategic recommendations and technical feedback on biotherapeutics trials and project milestones. Qualified candidates must possess specialized expertise in pharmaceutical development, pain management, and FDA regulatory review processes concerning toxicology and safety pharmacology. This engagement focuses on delivering high-level technical guidance to ensure the success of biologic drug discovery and development initiatives. The opportunity was posted on October 28, 2026, with a response deadline of November 5, 2026.

Omas Strategic Buying Center - Professional Services

POSTED

DEADLINE

GEO Geophysical Retrieval Algorithm DevelopmentThis subcontract, titled GEO Geophysical Retrieval Algorithm Development, involves the creation and implementation of geophysical retrieval algorithms for geostationary sensors supporting NASA Goddard Space Flight Center projects. The selected provider will work with prime contractors to develop, implement, and provide technical support for the integration and evaluation of spaceborne cloud and precipitation retrieval datasets. The project requires specialized expertise in satellite remote sensing and atmospheric science to deliver validated algorithms and comprehensive integration support. Managed through the NASA Shared Services Center under NAICS code 541715, the opportunity was posted on October 28, 2026, with a response deadline of November 2, 2026.

NASA Shared Services Center

POSTED

DEADLINE

Epidemiological Analysis & Public Health ResearchThis subcontract, titled Epidemiological Analysis and Public Health Research, supports prime contractors on CDC DNPAO projects through the Department of Health and Human Services. The scope of work involves performing advanced epidemiological analyses and public health research, specifically focusing on maternal-child nutrition. Key responsibilities include downloading and formatting surveillance data from sources such as NHANES, NHIS, BRFSS, YRBS, and NSCH, as well as designing hypothesis tests using regression models, conducting microsimulation modeling, and performing systematic reviews. The successful provider must demonstrate proficiency in R and Python to deliver critical outputs, including data tables, scientific manuscripts, and surveillance reports. The work is based in Atlanta and falls under NAICS code 541715. Interested parties should note the response deadline of November 10, 2026.

CDC Office Of Acquisition Services

POSTED

DEADLINE

Research Institution Partner (Non-Profit)This subcontract opportunity is for a registered non-profit research institution to partner with prime contractors on U.S. Air Force STTR projects. The primary objective is to conduct core scientific research to evaluate the technical feasibility of cyber resiliency within edge computing environments. Selected partners will be expected to leverage university laboratories, high-performance computing clusters, and specialized academic research software to produce research data, peer-reviewed findings, and contributions to technical reports. The opportunity is designated as a total small business set-aside under the SBIR/STTR mandate for organizations with fewer than 500 employees, falling under NAICS code 541715. Interested parties must submit their responses by November 25, 2026, at 5:00 PM. This effort is managed through the U.S. Department of Defense on behalf of the U.S. Air Force.

POSTED

DEADLINE

Edge and Fog Computing Architecture SpecialistThis subcontract opportunity for the U.S. Air Force focuses on research and development for cyber resiliency projects, specifically targeting the design of resilient architectures for fog and edge computing devices. The selected provider will be responsible for conducting feasibility studies, establishing technical milestones, and utilizing edge gateways, fog computing nodes, and embedded hardware. Key deliverables include a technical feasibility report and a Final Scientific or Technical Report. The project is a total small business set-aside under NAICS code 541715, requiring the contractor to have fewer than 500 employees. Due to the sensitive nature of the work, strict security compliance is mandatory, including CMMC Level 2 and adherence to NIST SP 800-171 and NIST SP 800-172 standards. Responses are due by November 25, 2026.

POSTED

DEADLINE

Quantum Algorithm & Benchmark DevelopmentThe Quantum Algorithm and Benchmark Development subcontract involves performing technical research and development for prime contractors on projects for the Defense Advanced Research Projects Agency. The scope of work focuses on developing benchmark instances for commercial application workloads, defining resource estimates, and translating high-value use cases into technical quantum algorithm requirements. These tasks will be executed using quantum computing simulators or early-stage quantum hardware, requiring specialized expertise in algorithm optimization and quantum complexity theory. The primary objective of the contract is the delivery of validated commercial application benchmarks. This opportunity is categorized under NAICS code 541715 and is associated with the Department of Defense. Interested parties should note the response deadline of December 30, 2026.

Defense Advanced Research Projects Agcy

POSTED

DEADLINE

Research Institution / University Partner (STTR)This subcontract opportunity is for a Research Institution or University Partner to support prime contractors on Department of Defense 2027 SBIR/STTR Phase I projects for the U.S. Air Force. The selected partner will be responsible for performing fundamental research, technical validation, and experiments to determine the feasibility of proposed concepts. Key deliverables include contributing to the Phase I technical volume, providing research data, and submitting detailed technical reports and feasibility findings. The solicitation was posted on October 28, 2026, with a response deadline of November 25, 2026. This is a total small business set-aside under the SBIR/STTR mandate for entities with fewer than 500 employees, falling under NAICS code 541715. The primary objective is to provide the academic and analytical rigor necessary to validate technical concepts during the initial phase of the program.

POSTED

DEADLINE

Specialized Cleaning Agent DevelopmentThis subcontract for the U.S. Navy involves the research and development of a specialized cleaning agent designed for TDR Tank Level Indicator projects. The selected contractor will analyze contaminants and formulate non-corrosive chemical compositions that are compatible with naval tank materials, with a strict requirement that no hexavalent chromium is used in the process. The project necessitates the use of laboratory facilities for chemical synthesis and material compatibility testing, culminating in the delivery of sample agents and detailed formulation reports. This opportunity is a Total Small Business Set-Aside under NAICS code 541715, specifically adhering to SBIR/STTR mandates for companies with fewer than 500 employees. Interested parties must submit their responses by November 25, 2026, to support prime contractors operating under the U.S. Department of Defense.

POSTED

DEADLINE

Distributed Engineering Testing and Analysis ServicesThe Distributed Engineering Testing and Analysis Services subcontract is a small business set-aside opportunity with the Naval Surface Warfare Center under the Department of Defense. The project focuses on performing distributed engineering tests to validate system performance for prime contractors on Navy NSWC PCD projects. Work will be performed in Panama City Beach, Florida, under NAICS code 541715. The scope of work involves executing Reliability Centered Maintenance and system safety analysis in accordance with MIL-STD-882E and MIL-STD-3034A. Utilizing telemetry systems and distributed testing rigs, the contractor is responsible for delivering comprehensive test reports, safety analysis documents, and RCM plans. Responses for this opportunity are due by December 3, 2026.

Naval Surface Warfare Center

POSTED

DEADLINE

in about 1 month

Senior Advisor SME - Pharmacology and PainThis subcontract opportunity is for a Senior Advisor Subject Matter Expert in Pharmacology and Pain to support the NIH HEAL Pain Therapeutics Development Program under the Department of Health and Human Services. The selected expert will provide strategic guidance and technical feedback to prime contractors and serve on the External Oversight Committee to advise on the discovery and development of neurological treatments and non-opioid pain medications. Key responsibilities include delivering strategic mentorship, producing technical reports, and participating in monthly teleconferences and annual on-site visits to the NIH campus in Bethesda, Maryland. The position requires a highly experienced professional in pharmacology to ensure the success of critical drug development initiatives. This is a Small Business Set Aside opportunity categorized under NAICS code 541715. Interested parties should note the tight response window, with the solicitation posted on October 28, 2026, and a deadline for responses set for October 30, 2026.

Asa Office Of The Assistant Secretary For Administration

POSTED

DEADLINE

Research Institution Collaborative PartnerThe Research Institution Collaborative Partner subcontract, issued by the U.S. Air Force under the Department of Defense, focuses on primary research and development for STTR projects. The selected partner will be responsible for conducting laboratory research, theoretical modeling, data analysis, and technical validation to assess the feasibility of proposed concepts. Key deliverables include technical reports, research findings, and comprehensive feasibility data. This opportunity is specifically set aside for small businesses under the SBIR/STTR mandate with fewer than 500 employees, and it requires the partner to be a non-profit research institution, such as a university or a Federally Funded Research and Development Center. Interested parties must submit their responses by November 25, 2026.

POSTED

DEADLINE

Luminescence-Based Sensor Development SpecialistThis subcontract opportunity for the U.S. Air Force involves the research and development of luminescence-based surface measurement techniques specifically for hypersonic ground test facility projects. The selected specialist will be responsible for creating theoretical frameworks, identifying stable luminescent phosphors suitable for non-oxygen environments, and designing optical measurement systems utilizing high-speed sensors and spectrometers. The primary deliverables include comprehensive technical data and feasibility analyses to support prime contractors. This is a Total Small Business Set-Aside under NAICS code 541715, requiring the contractor to have fewer than 500 employees. Due to the nature of the defense work, strict adherence to ITAR/EAR compliance and NIST SP 800-171/CMMC cybersecurity standards is mandatory. Interested parties must submit their responses by November 25, 2026.

POSTED

DEADLINE