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A--Intent to award a contract to the University of Connecticut

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W81NLC11573001Federal

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The U.S. Army RDECOM Contracting Center, Natick Contracting Division, intends to award a firm fixed price purchase order on a sole source basis to Instron for a collaborative research study titled "Research Study of Phospholipase CB in Freeze Trauma-Induced Skeletal Muscle Injury." This research aims to explore pharmacological interventions that can mitigate skeletal muscle injury resulting from extreme trauma in military personnel. The work will involve the University of Connecticut Health Science Center, which possesses unique capabilities, including proprietary methods and a patent application related to protecting skeletal muscle against injury. Their specialized expertise includes established injury models, advanced analytical techniques using Evans Blue Dye, and access to phospholipase CB null mice, which are essential for investigating the mechanisms of muscle protection and pharmaceutical efficacy. This procurement follows FAR Subpart 13.106-1(b)(1) and is not a request for proposals; rather, it is an intent to award without competition due to the university's distinctive qualifications and resources. Market research confirmed that no other entity can provide the required specialized resources, such as the unique mouse line and perfected injury assessment methods, critical for this ongoing study. Interested parties were invited to express their interest by a specified deadline, but the contracting process highlights the necessity of collaboration with this institution to continue advancing skeletal muscle injury research in support of military health. The contracting office managing this action is located in Natick, Massachusetts, with Jeffrey Bernard serving as the contract specialist point of contact.

General Info

Sole source fixed-price contract awarded to Instron for muscle injury research with UConn collaboration.

NAICS

611310 - Colleges, Universities, and Professional Schools

Place of Performance

MA

Set-Aside

NONE

Documents

0

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Organization & Contact Information

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AgencyDepartment Of Defense → W6QK Acc-Apg Natick
ContactsNo contacts available
OfficeNATICK, MA, 01760-5011, USA
Office AddressNATICK, MA, 01760-5011, USA
ContactsNo contact information available

Full Description

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Introduction: Pursuant to FAR Subpart 13.106-1(b)(1), the U.S. Army RDECOM Contracting Center, Natick Contracting Division, on behalf of the US Army Combat Feeding directorate, intends to award a firm fixed price purchase order on a sole source basis to: Instron, 825 University Ave, Norwood, MA 02062. THIS IS NOT A REQUEST FOR PROPOSALS. NO SOLICITATION DOCUMENT IS AVAILABLE. RESPONSES WILL BE USED FOR FUTURE ACQUISITIONS ONLY. 1. Nature and description of the supplies or services required to meet the agency's needs: Research Study of Phosphoilipase CB in Freeze Trauma-Induced Skeletal Muscle Injury. Ongoing collaborative research study to identify ways to reduce and/or prevent skeletal muscle injury in military personnel. 2. A demonstration that the proposed contractor is the only source available to provide these services or goods (i.e. unique qualifications, proprietary rights, etc.): To continue with our ongoing research efforts designed to use pharmacological interventions to mitigate skeletal muscle injury in response to extreme trauma, we are engaging in a collaborative project with the University of Connecticut Health Science Center. This company has several unique capabilities which make it a prime candidate for collaborative work. Dr. Bruce Liang at the University of Connecticut Health Science Center has submitted a patent application (U.S. Patent Application 12/054,523, ~ Methods to Protect Skeletal Muscle Against Injury", filed 25 March 2006. Dr. Bruce Liang and Dr. Edward Zambraski, Inventors. The investigators at the University of Connecticut Health Science Center have already performed pilot work with pharmacological agents, perfected injury models, and developed sophisticated methods to analyze skeletal muscle injury in vivo using Evans Blue Dye staining and analysis techniques. Moreover, the University of Connecticut had developed a line of phospholipase CB null mice, which are readily available for breeding and testing purposes. It is important that we have access to this line of mice, as phospholipase CB null mice are resistant to the protective effects of the Adenosine A3 receptor agonist, proving important clues indicating what aspects of skeletal muscle injury are not protected by pharmacological treatment with the Adenosine A3 Receptor Agonist. 3. A description of the market research that was conducted and the results, or a statement of the reason a market research was not conducted: The University of Connecticut Health Science Center is the only facility that has: a steady supply of phospholipase CB null mice; perfected methods of skeletal muscle injury in these mice and wild-type mice, to include eccentric, IfR, and blunt trauma type injuries and identified an effective means to measure skeletal muscle injury in vivo via Evans Blue Dye staining and analysis techniques. 4. Interested parties may identify their interest and capability to respond to this requirement to the U.S. Army RDECOM Contracting Center, Natick Contracting Division via e-mail to: contact@example.gov no later than 10:00am (EST) on July 25th, 2011. Contracting Office Address: Army Contracting Command - Aberdeen Proving Ground Natick Contracting Division Kansas Street, Building 1 Natick, MA 01760-5011 Point of Contact: Jeffrey Bernard, Contract Specialist (508)-233-6105 contact@example.gov

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