A -- NOTICE OF INTENT TO ENTER AGREEMENTS
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Idaho National Laboratory, operated by Battelle Energy Alliance under contract with the Department of Energy, has announced its intent to enter into agreements with NorthStar Nuclear Medicine, Inc. (NNM) to commercialize proprietary methods for recovering daughter isotopes, specifically actinium-225, from excess uranium-233 held at INL. This initiative aims to develop and implement patented processes to extract actinium-225 for use in human therapeutic applications, including clinical trials and treatments. BEA plans to enter an exclusive license agreement with NNM for the commercialization of this technology, alongside a cooperative research and development agreement to design a recovery process. Upon validation of the recovery plan, both parties intend to collaborate on the operation of a pilot-production facility to supply actinium-225 until Phase III clinical trials with related isotopes conclude. INL researchers have developed two distinct methods to extract actinium-225 from approximately 14 metric tons of mixed thorium isotopes containing roughly 40 grams of thorium-229. NNM has the capability to fund pilot plant development for one or both methods and distribute the recovered isotope to the medical community for therapeutic use. This effort is focused on advancing cancer treatment options through the availability of actinium-225, which is significant for its application in targeted therapies. The notice specifies that this is not a procurement opportunity, and inquiries can be directed to the designated BEA Technology Transfer and Commercialization representative.
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