This Government Contract opportunity was posted on February 11, 2010. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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A--R&D Estrogen Receptors in Lupus Modulators of Inflammotory Response

Awarded

VA-247-09-RP-0349Federal

Submission Closed09/25/2009, 12:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541720

New

Federal

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Countermeasures That Work (CMTW) Updates

Solicitation # 693JJ926R000067

The National Highway Traffic Safety Administration (NHTSA) is soliciting proposals for a single-award, Cost-Plus-Fixed-Fee (CPFF) completion contract to update the Countermeasures That Work (CMTW) evidence-based reference guide and its companion document, Countermeasures At Work (CMAW). The project involves developing the 13th and 14th editions of CMTW and the 2nd edition of CMAW, as well as updating the Electronic Countermeasures That Work (E-CMTW) website. The selected contractor will conduct comprehensive literature searches and synthesize research across eleven behavioral traffic safety program areas, updating approximately three to four chapters annually. The contract period consists of a twelve-month base period with four twelve-month options, for a total potential duration of sixty months. Award will be based on best value, with a primary emphasis on superior technical skills over the lowest cost. Evaluation factors include the offeror's understanding of research complexities, the soundness of the proposed approach, personnel qualifications, and corporate past performance. Deliverables must adhere to strict quality control standards, including the use of APA 7th edition style and rigorous anti-plagiarism compliance. All final text must be submitted in electronic format using minimal formatting to facilitate government printing. Proposals must be submitted in two separate volumes, technical and business, by November 5, 2026.

693JJ9 Nhtsa Office Of Acquistion

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Medical Regulatory Research and AnalysisThe Medical Regulatory Research and Analysis subcontract involves providing qualitative and quantitative research services for prime contractors supporting General Medical Council regulatory projects. The primary focus of the work is to conduct research on registered doctors who do not hold a licence to practise, analyzing the resulting data to offer contextual insights necessary for regulatory reform. The selected provider is responsible for drafting and delivering formal research reports that adhere strictly to GMC guidelines. Additionally, the contract requires the completion of a security questionnaire. This opportunity is categorized under NAICS code 541720, with a response deadline set for December 1, 2026.

General Medical Council (GMC)

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Research into Doctors Registered without a Licence to Practise

Solicitation # GMC2426

The General Medical Council (GMC) is seeking a research and development consultancy provider under solicitation GMC2426 to conduct a study on doctors registered with the GMC who do not hold a licence to practise. The primary objective of this research is to provide contextual insights that will inform future regulatory reform work. The project is estimated to run from January 4, 2027, to July 31, 2027, with a total estimated value of 58,333 GBP excluding VAT. This opportunity is noted as being particularly suitable for small and medium-sized enterprises (SMEs) and will be performed within the United Kingdom. The award process follows an open competition procedure where proposals are evaluated based on a weighted split of 80 percent for quality and 20 percent for commercial price. Interested parties must submit their tenders via the mytenders.co.uk portal by the deadline of December 1, 2026, at 12:00 pm. Required deliverables include a formal research report that must adhere to the GMC's specific guidelines for writing research reports. The primary point of contact for this solicitation is Gordon Duffus.

General Medical Council (GMC)

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21st CCLC Program EvaluatorThis subcontract opportunity is for a 21st CCLC Program Evaluator to conduct a statewide evaluation of the 21st Century Community Learning Centers program for prime contractors working with the West Virginia Department of Education. The selected provider will be responsible for developing and implementing evaluation frameworks for Year Two and Year Three, managing data collection processes, and analyzing program data to determine the overall impact of the initiative. The final deliverables include comprehensive evaluation reports and detailed data analysis. Qualified candidates must hold a Bachelor's degree in Education. The project is based in Charleston, West Virginia, and falls under NAICS code 541720. Interested parties should note that the response deadline is November 12, 2026, at 3:30 PM.

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ARFQ-0402-EDD2700000004-2 | Statewide Evaluation for the 21st CCLC Program

Solicitation # ARFQ-0402-EDD2700000004-2

The West Virginia Department of Education is seeking a statewide evaluator for the 21st Century Community Learning Centers program, authorized under Title IV, Part B of the Federal Elementary and Secondary Education Act. The selected contractor will be responsible for collecting, validating, and analyzing evaluation data, which includes conducting at least one annual on-site visit to five selected subgrantees and delivering one in-person presentation of findings in Charleston, West Virginia, each contract year. Services are anticipated to begin in January 2027, with a Statewide Evaluation Plan due within 60 calendar days of the effective start date. This fixed-amount agency contract will be awarded to the vendor that meets all minimum qualifications and mandatory requirements for the lowest overall total cost, calculated as the sum of the initial contract year and three optional renewal years. Deliverables must be provided in accessible formats, including Microsoft Word, searchable PDFs, and nonproprietary machine-readable datasets. Due to the nature of the work, the contractor must adhere to strict data privacy standards, including FERPA compliance and the execution of confidentiality and non-disclosure agreements. Bids must be submitted electronically via wvOASIS or delivered to the agency by November 12, 2026, at 10:30 AM EDT.

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PS- RFP for State of Alabama Historical Commission for 2025-2035 Statewide Historic Preservation Plan

Solicitation # SRC0000037417

The State of Alabama Historical Commission is soliciting proposals for professional services to develop and update the 2025-2035 Statewide Historic Preservation Plan. The primary objective is to create a concise, printed document that provides a vision for historic preservation in Alabama, including a summary of plan development, an assessment of historic and cultural resources, and guidance for management policies and strategies. The project must adhere to the Secretary of the Interior’s Preservation Planning and Professional Qualification Standards, as well as the HPF Grants Manual and 54 USC §302303. The selected contractor will be required to provide quarterly progress reports throughout the development process. Proposals must be submitted via Alabama Buys by November 30, 2026, at 4:30 PM CT, with an inquiry deadline of November 13, 2026. Evaluation is based on a weighted scoring system: Proposed Project Plan and Approach (40 points), Vendor Qualifications and Experience (35 points), Cost Proposal (20 points), and an Executive Summary (5 points). The initial contract term is two years from the date of the Governor's signature, with the possibility of three additional one-year renewals. Awardees must comply with various state certifications, including tax registration, immigration law compliance, and prohibitions against economic boycotts. The contract is subject to the Department of Finance Administrative Code and the Code of Alabama 1975, with specific provisions for non-appropriation of funds and proration.

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Comprehensive Final Program Evaluation and SynthesisThis subcontract, titled Comprehensive Final Program Evaluation and Synthesis, involves providing high-level program synthesis and impact evaluation for prime contractors working on projects for the Community Investments Office of the Air District in California. The selected provider will utilize both qualitative and quantitative research methodologies to analyze the cumulative effects on air quality and environmental inequities across 28 different grantees, ensuring all work adheres to established evaluation best practices. The primary deliverables for this engagement are a Final Program Evaluation Report and a Synthesis of Findings. The opportunity was posted on October 27, 2026, with a response deadline of December 1, 2026, and is categorized under NAICS code 541720.

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Program Evaluation Services for the Local Community Benefits Fund

Solicitation # 2026-040

Solicitation 2026-040, issued by the Community Investments Office of the Air District, seeks a contractor to provide program evaluation services for 28 Round 1 grantees of the Local Community Benefits Fund. The project is designed to support the Air District's mission of improving air quality, reducing environmental inequities, and mitigating climate change across nine Bay Area counties. The contract has an established budget of 1,500,000 dollars and an anticipated duration of up to six years. The work is divided into two primary phases: Phase A, focusing on indicator tracking technical assistance for early grant implementation, and Phase B, which covers output tracking, analysis, and periodic program evaluation, culminating in a final synthesis of findings during years five and six. The selection process involves a two-phase evaluation consisting of a proposal review and an interview. Proposals are evaluated based on technical merit, with a preference given to local businesses headquartered within the Air District's jurisdiction. In the event of a tie in scoring, the lower cost offer will be accepted. Key requirements for respondents include a detailed technical proposal, a separate cost proposal, a disclosure regarding the use of Generative AI, and a commitment to retain project records for five years. The deadline for electronic submission via the procurement portal is November 30, 2026, at 4:00 pm Pacific Time.

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Public Health Research and Evidence SynthesisThis subcontract for Public Health Research and Evidence Synthesis supports prime contractors working on projects for the Virginia Department of Health. The scope of work involves synthesizing Virginia-specific health data and analyzing practices from peer states to identify evidence gaps and research jurisdictional models. The selected provider will utilize public health databases to ensure a clear distinction between documented findings and assumptions. Deliverables include the production of concise research briefs, summaries, and presentation materials, all requiring full citations. The work is performed in Richmond, Virginia, under NAICS code 541720. Interested parties should note the response deadline of October 30, 2026.

Virginia Department of Health

POSTED

3 days ago

DEADLINE

in about 14 hours

AI Contract Overview

The Department of Veterans Affairs Medical Center intends to award a sole source contract to the Medical University of South Carolina for research and development services focusing on the role of estrogen receptors in lupus and the modulation of inflammatory responses. The project involves utilizing cell culture and molecular techniques to analyze estrogen receptor expression and cellular localization. This work is part of a funded VA Merit Review Grant aimed at defining gender-based differences in immune responses, which is critical for understanding autoimmune diseases and potential bio-warfare responses. The contract is justified as a sole source acquisition under the authority for essential research capability, specifically to utilize the expertise of Dr. Subha Dasgupta. Dr. Dasgupta possesses specialized knowledge in estrogen receptors and animal models of autoimmunity and is identified as the only scientist in the Charleston area capable of performing these experiments. Because he is not a US citizen and cannot be hired as a VA employee, the services will be contracted through the Medical University of South Carolina.

General Info

Agency

N/A

Contract Value

$45,000

NAICS

541720 - Research and Development in the Social Sciences and Humanities

Place of Performance

Not specified

Set-Aside

NONE

Awardee

DEPARTMENT OF EDUCATION, SOUTH CAROLINA;169 ASHLEY AVE;CHARLESTON;SC;294250001

Award Issued Date

09/25/2009, 12:00:00 AM UTC

Documents

No documents available

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Timeline

PhaseAwarded

PostedSep 5

Presolicitation

AwardedSep 25

Contract was awarded

Submission Closed

09/25/2009, 12:00:00 PM UTC

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Full Description

Justification for Other than Full and Open Competition Department of Veteran Affairs Medical Center Augusta, Georgia For Research and Development Services Role of Estrogen Receptors in Lupus-Modulators of the Inflammatory Response 1. REQUIRING ACTIVITY: The Department of Veterans Affairs Medical Center, 109 Bee Street, Charleston, SC 29401 2. CONTRACTING ACTIVITY: The Department of Veterans Affairs Medical Center, Network Logistics Contracting Activity, 1 Freedom Way, Augusta, GA 30909 3. PROPOSED ACTION: The Department of Veterans Affairs Medical Center Network Logistics Contracting Activity Augusta, GA intends to award a sole source contract to Medical University of South Carolina, Department of Medicine, Division of Rheumatology and Immunology Room 912, P.O. Box 250637, Charleston, SC 29425 The Medical University of South Carolina is a Large Business. 4. DESCRIPTION OF REQUIREMENT: The contractor will provide research and development services for the cell culture and molecular techniques for analyzing estrogen receptor expression and estrogen receptor into cellular localization. 5. STATUTORY AUTHORITY PERMITTING OTHER THAN FULL AND OPEN COMPETION: 6.302-3(a)(2)(ii), Industrial mobilization; engineering, developmental, or research capability; or expert services. 6. NATURE OF ACQUISTION OT MEET THE AUTHORITY CITED IN PARAGRAPH 5: The work proposed to be performed is an aim of a currently funded VA Merit Review Grant from VA Central Office in Washington D.C. The overall goal of the work is to define the role of estrogen receptors in immune responses in females. To confirm this very important finding, the additional experiments outlined in the Statement of Work and the Merit Grant needs to be completed in a timely fashion. The importance for the VA is that the work will define mechanisms underlying differences in the immune responses of females vs. males. These findings are important for understanding autoimmune diseases where females predominate and also for potential bio-warfare to understand gender based responses to the pathogen. 7. LOCATE SOURCE: This contract is proposed for completion of the aims by PhD Scientist, Dr. Subha Dasgupta, at the Medical University of South Carolina (MUSC), who is familiar with the techniques and scientific are. There is no scientist at any other institution in the Charleston area capable of these experiments. Dr. Dasgupta is currently a staff scientist at MUSC. As he is not a US citizen, he cannot be hired as a VA employee to perform the duties. He has expertise in estrogen receptors and animal models of autoimmunity, both critical aspects of this contracted work. 8. CUSTOMERS SUBMISTION OF PRICE ANALYSIS: The Customer has submitted his price analysis in accordance with the allocation of the VA Merit Grant for the six (6) months. 9. FUTURE ACTIONS TO OVERCOME BARRIER TO FULL AND OPEN COMPETITION: In accordance with FAR 6.302-3(a)(2) (ii) this acquisition is exempt because it necessary to award the contract to a particular source or sources in order to establish or maintain an essential engineering, research, or development capability to be provided by an educational or other nonprofit institution or federally funded research and development center. 10. SYNOPSIS: This acquisition will be advertised in FedBizOpps. 11. I hereby certify that this justification is accurate and complete to the best of my belief and knowledge. 9/4/09 _______________________________ ________________ AGATHA S. PALMER Date Contracting Officer