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A--Request for information for Peptide Synthesis Research services for both individual peptides and peptide arrays

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W911QY-335Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

AI Contract Overview

The contract seeks to address the ongoing peptide synthesis needs of the Natick Soldier Research Development and Engineering Center (NSRDEC), which currently supports five active research projects with plans for future projects requiring similar services. Peptides of varying sequences and complexities are essential for these efforts, and the government requires continuous synthesis capabilities in two primary categories: linear peptides and cyclized peptides, with an additional possibility for peptide arrays. Historically, peptide synthesis services were procured through individual orders leading to inefficiencies and delays under current procurement procedures. This contract aims to streamline the process by establishing a performance-based service arrangement that meets the government’s requirements efficiently and cost-effectively over multiple years. The contractor will be responsible for synthesizing peptides meeting specified sequences, purities, and quantities as dictated by individual delivery orders. Quality control measures are stringent, requiring reverse phase high-performance liquid chromatography (RP-HPLC) and Mass Spectrometry analysis, with certificates of analysis provided with each shipment. Peptide arrays require additional handling, including uncoupled peptides delivered in separate containers with purification steps. Maintaining schedule adherence, cost efficiency, and delivering high-quality products are critical performance objectives. Because some requirements necessitate direct communication and collaboration, the government favors contractors local to the NSRDEC facility in Natick, Massachusetts, to facilitate face-to-face interaction and support.

General Info

Contract establishes multi-year peptide synthesis services for NSRDEC, ensuring quality, efficiency, and local collaboration.

Agency

Department Of Defense → W6QK Acc-Apg Natick

NAICS

541711 - Research and Development in Biotechnology

Place of Performance

Set-Aside

NONE

Documents

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Timeline

PostedMar 31

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Organization & Contact Information

AgencyDepartment Of Defense → W6QK Acc-Apg Natick

ContactsNo contacts available

OfficeNATICK, MA, 01760-5011, USA

Organization / AgencyDepartment Of Defense → W6QK Acc-Apg Natick

Office AddressNATICK, MA, 01760-5011, USA

ContactsNo contact information available

Full Description

Peptides are central to numerous research efforts at the Natick Soldier Research Development and Engineering Center (NSRDEC) due to their extensive sequence landscape, chemical diversity and broad range of functionality. There are currently five on-going research projects which require peptide synthesis with additional project anticipated. The Government expects this need for peptide synthesis to continue for a number of years. To date, each project has identified the need for peptide synthesis work as it occurs; and separate orders/contracts have been awarded for peptide synthesis. With the modification to the procurement procedures, the past approach has become time consuming leading to delays which has been impeding progress to individual projects. This Request for Information should be considered an open call for providing the government peptide synthesis needs. The Government requires two general classes of peptide synthesis: (1) linear peptide synthesis; and (2) cyclized peptide synthesis. Additionally, the Government may require peptide arrays. This performance-based service contract incorporates the following performance objectives: (1) Synthesize peptides with specified sequence and purity (2) adherence to contract schedule, milestone, and delivery requirements, and (3) efficient and effective cost control. The contractor's primary focus shall be to synthesize peptides based on the Governments specified sequence and purity. The specific sequence, purity and quanity for each delivery order will be include on the individual delivery order. All peptide synthesis shall include reverse phase high-performance liquid chromatography (RP-HPLC) and Mass Spectrometry analysis. A certificate of analysis shall be required with each shipment. In addition, peptide arrays will require peptides to be uncoupled, in individual containers with a purification step. It is the contractors responsibility to employ the necessary resources to ensure accomplishment of these objectives. The government expects some face-to-face contact to ensure some specific requirement are understood and successfully accomplished, therefore we are looking for contractors who are local to the NSRDEC.