This Government Contract opportunity from Department Of Health And Human Services was posted on September 29, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Advanced Development of OXOS X3, a Point-of-Care Diagnostic X-Ray Imaging System for Detection of Fracture and other Trauma

Awarded

75A50126C00011Federal

Submission Closed09/25/2026, 04:00:00 AM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541714

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AJ12--Development/Production - Kidney GEC-Specific AAV Vector

Solicitation # 36C24E27Q0009

The Department of Veterans Affairs is issuing a Sources Sought notice to identify capable vendors for the development and production of a kidney glomerular endothelial cell specific adeno-associated virus AAV vector. This project, funded by a VA ORD Merit award, aims to create a homing peptide enabled vector platform to target the glomerular endothelium to treat kidney injury and disease while reducing off target transduction. The scope of work is divided into three primary tasks: the engineering and incorporation of targeting peptides into the AAV capsid, testing vector binding and internalization in kidney tissue slices, and evaluating the specificity and efficiency of the modified vector through bioluminescence imaging and in vivo biodistribution studies. Qualified contractors must possess extensive onsite resources, including BSL 2 laboratories, specialized DNA and RNA facilities, and advanced instrumentation such as the Agilent Fragment Analyzer and various qPCR platforms. Vendors must demonstrate proven success in animal and human cell vector delivery and maintain full compliance with AAALAC and FELASA health standards. The government requires quarterly reporting, weekly videoconferences, and biannual face to face meetings. All generated data will be subject to Government Purpose Rights, and contractors must adhere to strict federal records management and information security protocols. Interested parties must submit a capability statement, relevant literature, and socio economic status details under NAICS 541714 by November 4, 2026.

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National Institutes Of Health

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National Institutes Of Health

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Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)

Solicitation # RFA-AI-28-012

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National Institutes Of Health

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Immune Tolerance Network (UM1 Clinical Trial Required)

Solicitation # RFA-AI-28-005

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National Institutes Of Health

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Immune Tolerance Network (UM1 Clinical Trial Required)

Solicitation # RFA-AI-28-005

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, is seeking applications under solicitation RFA-AI-28-005 to continue the Immune Tolerance Network. The primary goal of this initiative is the development of tolerogenic therapies targeting autoimmune diseases, allergic diseases and asthma, and immune-mediated consequences of transplantation. The network is tasked with the core functions of designing and conducting clinical trials, performing integrated mechanistic studies, and sharing the resulting data. This federal solicitation was posted on October 20, 2026, and requires responses by January 30, 2027. As a UM1 clinical trial requirement, the project emphasizes a collaborative approach to advancing medical treatments for immune-mediated disorders through rigorous clinical research and analysis.

National Institute Of Allergy And Infectious Diseases

POSTED

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Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)

Solicitation # RFA-AI-28-012

The National Institute of Allergy and Infectious Diseases, under the National Institutes of Health, is soliciting proposals for the Translational Centers Using Microphysiological Systems for Infectious Diseases under solicitation number RFA-AI-28-012. This initiative aims to establish a consortium of centers focused on refining and validating human tissue models to study infectious diseases and test medical interventions. By leveraging New Approach Methodologies, the program seeks to create in vitro systems that capture human variability and patient-specific characteristics, ultimately accelerating the development of safer treatments while reducing costs and the reliance on laboratory animals. The primary objective is to advance these microphysiological systems to a level of regulatory qualification that encourages adoption by product developers and ensures regulatory acceptance. Interested parties must submit their responses by the deadline of January 30, 2027. This federal opportunity specifically focuses on bridging the gap between current research and regulatory use for infectious disease models, though it is noted that clinical trials are not allowed under this specific funding mechanism.

National Institute Of Allergy And Infectious Diseases

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Solicitation # PROC-9177507

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Grains Research and Development Corporation

POSTED

DEADLINE

Pre-Clinical Models of Infectious Diseases

Solicitation # 75N93027R00003

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National Institutes Of Health Niaid

POSTED

DEADLINE

Alternative Protein Technologies for Military Field Feeding

Solicitation # W911QY27ALTPROTEINS

The US Army Combat Capabilities Development Command Soldier Center is seeking information from Massachusetts-based offerors to identify innovative alternative protein technologies for integration into military rations. The objective is to enhance food supply chain resilience and provide nutrient-dense, lightweight food options for warfighters. Areas of interest include fermentation and biomanufacturing processes, innovative product development for shelf-stable rations, consumer research for military acceptability, and the optional provision of GRAS-certified food samples. Specifically, the government is excluding any solutions involving cell-cultured, lab-grown meat, or insect proteins, focusing instead on technologies between TRL 4 and 6. This is a Sources Sought Announcement for market research purposes and not a formal solicitation or a promise of future funding. Interested parties must submit a BAA preproposal by November 23, 2026, including a technical approach, past performance, and a rough order of magnitude cost estimate. Submissions must be sent via email to the designated points of contact and include the offeror's business size, NAICS code, and CAGE code to verify their Massachusetts location.

W6QK Acc-Apg Natick

POSTED

2 days ago

DEADLINE

in about 1 month

AI Contract Overview

Contract 75A50126C00011, awarded to OXOS Medical, Inc. by the Department of Health and Human Services through BARDA, provides 48,891,652.86 dollars for the advanced development and FDA clearance of the OXOS X3. This ultra-portable, high-output general radiography and fluoroscopy system is engineered as a threat-agnostic medical countermeasure designed to weigh under 25 pounds and deliver up to 100 kV / 15 mA. The system aims to eliminate transport-to-imaging bottlenecks during mass casualty incidents, such as nuclear detonations, conventional blasts, or large-scale trauma surges, by bringing hospital-grade diagnostic capabilities directly to the point of need. The OXOS X3 is intended for use in high-volume emergency departments, temporary field hospitals, and triage sites to restore the diagnostic foundation of the ATLS primary survey where current portable assets are insufficient. Performance of the contract is based in Atlanta, Georgia, under NAICS code 541714. The project focuses on improving survival rates in critical trauma events by enabling the immediate detection of fractures and other trauma through point-of-care imaging.

General Info

BARDA awarded OXOS Medical $48.9 million for developing the portable OXOS X3 system.

Agency

Department Of Health And Human Services → Barda - Aspr / Daappo / Barda Dcma

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)

Place of Performance

Atlanta, GA, 30309, USA

Set-Aside

NONE

Documents

Award Notice: 75A50126C00011 - OXOS Medical, Inc.

award

Low

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Timeline

PhaseAwarded

PostedSep 29

special-notice

AwardedOct 21

Contract was awarded

Submission Closed

09/25/2026, 04:00:00 AM UTC

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Organization & Contact Information

AgencyDepartment Of Health And Human Services → Barda - Aspr / Daappo / Barda Dcma

Contacts2 people available

OfficeWASHINGTON, DC, 20515, USA

Organization / AgencyDepartment Of Health And Human Services → Barda - Aspr / Daappo / Barda Dcma

Office AddressWASHINGTON, DC, 20515, USA

Contacts

Erin Greninger Contracting Officer

contact@example.gov

Joann Kambaja Contract Specialist

contact@example.gov

+1 (555) 000-0000

Full Description

Transform trauma response by bringing hospital-grade imaging directly to the point of need by developing and receiving FDA clearance of the OXOS X3, an ultra-portable, high-output general radiography and fluoroscopy system engineered to function as a threatagnostic medical countermeasure (MCM). Designed to weigh under 25 pounds and deliver up to 100 kV / 15 mA at the point of need, X3 augments the transport-to-imaging bottleneck that currently degrades survival in mass casualty incidents (MCIs) involving nuclear detonation, conventional blast, or large-scale trauma surge events. By bringing hospital-grade diagnostic capability directly to the casualty, whether in a high-volume Emergency Department, a temporary field hospital, or a triage site, X3 restores the diagnostic foundation of the ATLS primary survey at every step where current portable assets fail.