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AI/ML Model Development for Bio-Sequence Prediction

Active
Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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This subcontract, titled AI/ML Model Development for Bio-Sequence Prediction, is issued under the National Science Foundation's Tip - Core Programs. The project focuses on the creation of advanced AI and machine learning models designed to predict protein-molecule interactions for prime contractors working on NSF X-Labs bioengineering initiatives. The scope of work includes training models on biological data, developing predictive algorithms, and utilizing high-performance computing to integrate experimental data into machine learning loops. The successful contractor will be responsible for delivering validated algorithms, predictive software models, and robust data integration pipelines. This opportunity falls under NAICS code 541511 and was posted on October 14, 2026, with a response deadline set for February 8, 2027.

General Info

Subcontract for AI/ML model development predicting protein-molecule interactions for NSF bioengineering initiatives.

NAICS

541511 - Custom Computer Programming Services

Place of Performance

1180, VA, USA

Set-Aside

NONE

Documents

This scope was carved out of NSF-Topic4-FY26-XLabsSequence-to-Function.

The full solicitation package (5 documents), including the RFP, is on the prime solicitation, not on this scope.

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NSF X-Labs Initiative - From Sequence to Function

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Timeline

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Organization & Contact Information

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AgencyNational Science Foundation → Tip - Core Programs
ContactsNo contacts available
OfficeN/A
Office AddressN/A
ContactsNo contact information available

Full Description

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Develops advanced AI/ML models to predict protein-molecule interactions for prime contractors on NSF X-Labs bioengineering projects. Trains models on biological data, develops predictive algorithms for protein-molecule interactions, and integrates experimental data into ML loops using high-performance computing. Delivers predictive software models, validated algorithms, and data integration pipelines.

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NAICS: 541714
New
Federal
NSF X-Labs Initiative - From Sequence to Function
Solicitation # NSF-Topic4-FY26-XLabsSequence-to-Function
The National Science Foundation Directorate for Technology, Innovation and Partnerships is soliciting written proposals for the NSF X-Labs initiative, specifically focusing on the bioengineering technical domain from sequence to function. This opportunity is issued under the Other Transactions Agreement Solutions Offering and utilizes Other Transaction contracts pursuant to 42 U.S.C 19116, meaning it is neither a FAR-based procurement nor a financial assistance instrument. The program is structured in phases, beginning with Phase 0, which lasts approximately 9 to 12 months starting in September 2027, followed by a potential Phase 1 lasting 24 to 36 months starting in June 2028. All work must be performed within the United States. The selection process is a two-step competitive evaluation consisting of a written proposal and a subsequent oral presentation for selected teams. Proposals are evaluated based on team qualifications, structure, mission clarity, and outcomes. Lead organizations must be registered in the System for Award Management and provide a Unique Entity Identifier. Due to the nature of the bioengineering domain, teams must provide specific plans for biosafety and biosecurity, including assessments of dangerous gain-of-function. Awards are milestone-based, with payments scheduled quarterly upon the successful completion of documented technical exit criteria. Organizational Conflicts of Interest are managed using FAR Subpart 9.5 as a framework, requiring full disclosure of any potential conflicts to the Agreements Officer Representative. Written proposals must be submitted as PDFs via the NSF submission portal by February 8, 2027.
Research and Development in Biotechnology (except Nanobiotechnology)

POSTED

2 days ago

DEADLINE

in 4 months
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