This Pre-Solicitation opportunity from Department Of Veterans Affairs was posted on July 16, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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AJ13--Pharmarcokinetics for Experimental Rheumatoid Arthritis treatment

Closed

36C24526Q0669Federal

Submission Closed07/31/2026, 01:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 112990

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AI Contract Overview

The Department of Veterans Affairs, through its Network Contracting Office 05, is preparing to solicit a contractor to conduct preclinical toxicology and pharmacokinetic studies for an experimental joint-targeted liposomal delivery system designed to treat Rheumatoid Arthritis. The work will include GLP-compliant single-dose intravenous toxicity studies in adult rats with assessments such as clinical observations, body weight and food intake tracking, blood chemistry, necropsy, and histopathology, along with pharmacokinetic studies that may be GLP or non-GLP, involving IV dosing, timed blood sampling, plasma processing, and LC-MS/MS analysis of dexamethasone and its metabolite 6-hydroxydexamethasone to determine key pharmacokinetic parameters. A detailed final written report encompassing all toxicity findings, pharmacokinetic data, and analytical results is required. The performance location will be the contractor’s own laboratory, with an anticipated performance period of one year from September 15, 2026, through September 14, 2027. This pre-solicitation notice is for market research purposes only and does not constitute an invitation to bid or a commitment to award a contract. The formal solicitation, identified by number 36C24526Q0669 and classified under NAICS code 112990, will be issued after market research is complete, with a response deadline of July 31, 2026. All inquiries should be directed to Contract Specialist Robert O’Keefe Jr. at robert.okeefejr@va.gov.

General Info

VA seeks contractor for GLP toxicology and pharmacokinetic studies of liposomal dexamethasone for rheumatoid arthritis, one-year period.

Agency

Department Of Veterans Affairs → 245-NETWORK Contract Office 5 (36C245)View Agency

NAICS

112990 - All Other Animal ProductionView NAICS

Place of Performance

Contractor's Lab/Facility See Sources Sought Notice for Details, MD, 21218, USA

Set-Aside

NONE

Documents

(2)

36C24526Q0669 Pre-Solicitation Notice for Arthritis Therapy PK and Toxicity Studies

DOCX•presolicitation

Sources Sought Notice 36C24526Q0669 - Arthritis Therapy Toxicity and Pharmacokinetics

DOCX•sources-sought

AI Contract Breakdown

Uniform Contract Format

Timeline

PhaseClosed

PostedJul 16

Sources Sought

Type ChangedJul 16

Sources Sought → Presolicitation

Response DeadlineJul 31

Deadline has passed

Submission Closed

07/31/2026, 01:00:00 PM UTC

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Organization & Contact Information

AgencyDepartment Of Veterans Affairs → 245-NETWORK Contract Office 5 (36C245)

Contacts1 person available

OfficeLINTHICUM, MD, 21090, USA

Organization / Agency

Department Of Veterans Affairs → 245-NETWORK Contract Office 5 (36C245)

View Agency Profile

Office AddressLINTHICUM, MD, 21090, USA

Contacts

Robert O'Keefe JrContracting Officer

contact@example.gov

Full Description

PRE SOLICITATION NOTICE
Department of Veterans Affairs Network Contracting Office (NCO) 05 Title: A Joint Targeted Drug Delivery Approach for Arthritis Therapy Toxicity and Pharmacokinetics
The Department of Veterans Affairs (VA), Network Contracting Office (NCO) 05, intends to issue a solicitation for preclinical toxicology and pharmacokinetic (PK) studies to support advancement of an experimental joint targeted liposomal delivery system for Rheumatoid Arthritis therapy. This requirement involves GLP compliant toxicity studies and GLP or non GLP PK studies in adult rats.
The forthcoming solicitation will seek a contractor capable of performing:
GLP single dose IV toxicity studies including clinical observations, weight/food intake monitoring, blood chemistry assessments, necropsy, and histopathology. GLP or non GLP pharmacokinetic studies including IV dosing, timed blood collection, plasma processing and storage, LC MS/MS analysis of dexamethasone and 6 hydroxydexamethasone, and calculation of PK parameters. A comprehensive final written report covering toxicity results, PK data, and analytical findings.
Place of performance will be the contractor s laboratory. The anticipated period of performance is one year, approximately September 15, 2026 through September 14, 2027.
This notice is issued solely for informational purposes. A formal solicitation and the Government s acquisition strategy will be issued after completion of market research.
This notice does not constitute a solicitation and does not commit the Government to award a contract.
Point of Contact: Robert O Keefe Jr., Contract Specialist Email: robert.okeefejr@va.gov