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Automated Cell Counter

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75N98026Q00775Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

AI Contract Overview

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The National Institutes of Health, through the Liver Diseases Branch, is seeking an image-based automated cell counting system to replace manual microscopy-based white blood cell quantification in clinical research involving patients with liver disease. The system must provide dual-channel fluorescence and brightfield imaging to accurately differentiate between live and dead cells, distinguish white blood cells from red blood cells, and reduce inter-operator variability. It must process a minimum of eight samples per slide, analyze volumes as small as 10 microliters, and complete each count in under 60 seconds while allowing users to capture two, four, or eight images per sample. The instrument must support a broad range of sample types including mouse immune cells, human blood lymphocytes, bone marrow cells, and hepatocytes, and must be compatible with existing laboratory workflows through customizable, saveable, and retrievable experimental protocols. It must be compact, fitting within a 15-inch by 10-inch bench space, and fully compliant with 21 CFR Part 11 requirements including audit trails, user access controls, and electronic signatures. The system must come with a minimum 12-month manufacturer’s warranty. This procurement is issued under solicitation number 75N98026Q00775 as a presolicitation with no set-aside, classified under NAICS code 334516. Responses are due by July 21, 2026, with the opportunity posted on July 10, 2026. The system will be delivered and used at the NIH facility in Bethesda, Maryland. Primary contact for inquiries is John Burton, reachable via email at burtonjo@mail.nih.gov. The acquisition is managed by the Department of Health and Human Services under the Office of Acquisition and Logistics.

General Info

NIH seeks automated cell counter for liver disease research with fluorescence, brightfield, 21 CFR Part 11 compliance, and compact design.

Agency

Department Of Health And Human Services → National Institutes Of Health OlaoView Agency

NAICS

334516 - Analytical Laboratory Instrument ManufacturingView NAICS

Place of Performance

Bethesda, MD, 20892, USA

Set-Aside

NONE

Documents

(1)

Automated Cell Counter Requirements for Liver Diseases Branch

DOCX•sow

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Timeline

PhasePresolicitation
Posted

Presolicitation

Response Deadline

Submission deadline

Response Deadline

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health Olao
Contacts1 person available
OfficeBETHESDA, MD, 20892, USA
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health Olao
View Agency Profile
Office AddressBETHESDA, MD, 20892, USA
Contacts
John Burton
contact@example.gov

Full Description

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Requirements:


The Liver Diseases Branch requires an automated cell counter to support ongoing clinical research studies involving immune cells obtained from patients with liver disease. These studies require the isolation and quantification of white blood cells for downstream research analyses. 


Currently, white blood cells are counted manually using microscopy. To improve efficiency, increase counting throughput, enhance differentiation between white blood cells and red blood cells, distinguish live and dead cells, and reduce inter-operator variability, the laboratory requires an image-based automated cell counting system with dual-channel fluorescence and brightfield imaging capabilities. 


The following product features and characteristics are required: 


  • The system shall provide compatibility with existing laboratory workflows and support the use of customizable and saved experimental protocols for ongoing research studies. 

  • The system shall be capable of processing a minimum of eight samples on a single slide. 

  • The system shall complete cell counting in less than 60 seconds and provide the ability to capture two, four, or eight images per sample. 

  • The system shall incorporate dual-channel fluorescence and brightfield imaging capabilities for cell counting and viability assessments.  

  •  The system shall support analysis of a wide range of sample types, including mouse immune cells, bone marrow cells, human blood lymphocytes, hepatocytes, and other primary cell populations. 

  • The system shall be capable of analyzing sample volumes as small as 10 microliters. 

  • The system shall allow users to customize, store, and retrieve commonly used experimental settings and analysis protocols. 

  • The system shall be capable of supporting 21 CFR Part 11 compliance through available audit trail, user access control, and electronic signature functionality. 

  • The system shall have a compact footprint suitable for placement on laboratory bench space approximately 15 inches deep and 10 inches wide. 
  • The system shall include a minimum 12-month manufacturer's warranty. 

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