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Bioinformatics & Quantitative Framework Development

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Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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This subcontract for Bioinformatics and Quantitative Framework Development supports prime contractors on NIH IGVF Consortium projects. The primary objective is to develop quantitative research frameworks designed to detect the joint effects of genomic variants, specifically focusing on the classification of additive versus beyond additive interactions and the creation of predictive methods for variant combinations. Execution of these tasks requires the use of high-performance computing clusters and advanced statistical modeling software. The project is managed under the National Institutes of Health within the Department of Health and Human Services. The selected provider must ensure strict compliance with NIH cybersecurity and data sharing guidelines. Key deliverables include comprehensive framework documentation and the final predictive models. The response deadline for this opportunity is December 14, 2026.

General Info

Subcontract for NIH bioinformatics frameworks to detect genomic variant interactions by December 14, 2026.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

Not specified

Set-Aside

NONE

Documents

This scope was carved out of RFA-HG-27-009.

The full solicitation package (1 document), including the RFP, is on the prime solicitation, not on this scope.

View the prime solicitation

Genomic Variant Interactions With Other Variants Or The Environment (UM1 Clinical Trials Not Allowed)

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Timeline

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
ContactsNo contacts available
OfficeN/A
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health
Office AddressN/A
ContactsNo contact information available

Full Description

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Develops quantitative research frameworks for prime contractors on NIH IGVF Consortium projects to detect joint effects of genomic variants. Creates frameworks to classify additive vs. beyond additive interactions and develops predictive methods for variant combinations. Utilizes HPC clusters and advanced statistical modeling software. Complies with NIH data sharing and cybersecurity guidelines. Delivers framework documentation and predictive models.

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