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This Government Contract opportunity was posted on October 20, 2016. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

Bioinformatics resource Centers for Infectious Diseases

Awarded
NIH-NIAID-RDSS-16-NIHAI2016BRCFederal

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The Government has awarded a sole-source modification to contract HHSN272201400027C, modification 07, under the Bioinformatics Resource Centers for Infectious Diseases program. This modification increases the level of effort by adding direct labor hours to option period 2 to continue the development and support of antimicrobial resistance related data and computational services. The award was made pursuant to FAR Subpart 6.3, allowing for competition other than full and open. The primary objective is to extend the PATRIC infrastructure across five key areas: advancing DNA-level antimicrobial resistance annotation, identifying and predicting mobile genetic elements, and analyzing AMR features within complex microbial communities. Additionally, the scope includes enhancing AMR data models and metadata support, as well as developing new user-facing tools and visualizations, such as an extended genome browser and improved phylogenetic tree viewers.

General Info

Agency

N/A

Contract Value

$1,374,994

NAICS

541711 - Research and Development in Biotechnology

Place of Performance

Not specified

Set-Aside

NONE

Award Issued Date

Documents

0

No documents available

Documents will appear here when they are available.

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Timeline

PhaseAwarded
Posted

Award Notice

Awarded

Contract was awarded

Submission Closed

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Organization & Contact Information

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AgencyN/A
Contacts2 people available
OfficeN/A
Organization / Agency
N/A
Office AddressN/A
Contacts
Stanley A. KnightContracting Officer
Miranda S. Adamscontract specialist

Full Description

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This notice is provided in accordance with Federal Acquisition Regulation (FAR) 5.201(b)(1)(ii). The Government has awarded a sole-source modification to contract # HHSN272201400027C, modification 07. The contract modification is for additional level of effort, to add direct labor hours to option period 2. The objective of this award is to increase the level of effort available to continue development of and support for antimicrobial resistance (AMR) related data and computational services. Specifically, this modification will extend the PATRIC infrastructure to achieve the following aims: A. Advancing Antimicrobial Resistance Annotation at the DNA-level 1. Gather and curate DNA sequence level variants associated with AMR. 2. Build a computational framework for projecting DNA sequence level variants. 3. Project DNA sequence level variants. B. Identifying, Predicting and Annotating Mobile Genetic Elements 1. Build a database of mobile genetic elements. 2. Identify and predict mobile elements. 3. Refine the prediction workflow and distribution. C. Identifying AMR Features and Genomes in Complex Microbial Communities 1. Create search infrastructure for mining metagenomic data. 2. Explore methods for targeted assembly. 3. Construct an environmental AMR database. 4. Make environmental AMR sequences available in PATRIC tools. 5. Develop metagenomic AMR analysis services. D. AMR Data and Data Models 1. Enhanced support for antibiotics and AMR metadata. 2. Extend Solr schema to support AMR features 3. Construct AMR variant protein families. E. New Visualizations and User Facing Tools and Services 1. Contextual representation of AMR features. 2. AMR panel data summaries and viewer. 3. Extended genome browser to display DNA variants and mobile elements. 4. Enhanced protein family sorter. 5. Enhanced MSA viewer. 6. Enhanced phylogenetic tree viewer. This contract modification was awarded pursuant to FAR Subpart 6.3, "Other than Full and Open Competition."

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