ChemBridge IONCore and IONSet Library Compounds, or Brand Name Equal Items

(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. (ii) The solicitation number is NIHDA201800507 and the solicitation is issued as a request for quotation (RFQ). This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures; FAR Subpart 13.5-Simplified Procedures for Certain Commercial Items; and FAR Part 12-Acquisition of Commercial Items, and is not expected to exceed the simplified acquisition threshold. (iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2005-100, dated August 22, 2018. (iv) The associated NAICS code 325413 and the small business size standard 1,250 employees. This requirement is full and open with no set-aside restrictions. (v) Generic Name of Product: Chemical Libraries. (vi) Purchase Description: Two (2) brand name or equal chemical libraries with a combined total of 8,118 specific compounds equivalent to the following brand name items: IONCore Library Compounds (Regular Stock Level), quantity: one (1). IONSet Library Compounds (Regular Stock Level), quantity: one (1). Manufacturer: ChemBridge Corporation https://www.chembridge.com/documents/IONCore_IONSet_Libraries.pdf Salient characteristics: The brand name equal items must meet the following salient physical, functional, or performance characteristics of the brand name item to be acceptable for award: - The small molecule libraries should be comprised of known ion channel modulators, as well as pharmacophore-derived potential modulators, across a variety of channel families (including but not limited to voltage-gated channels such as calcium, potassium, sodium channels and ligand-gated channels such as 5-HT3, GABA, glycine, nAChR, and PCP receptors). - The Contractor must be able to provide the NCATS DPI with 8,118 compounds at 4mg/powder or 800ul/10mM DMSO solution each, packaged in NCATS supplied Matrix tubes at 88 compounds per plate. - Each small molecule must be guaranteed to have a purity of >90% (accuracy +/-5%) that is to be confirmed by NMR and/or LCMS spectra. - In addition to the molecules themselves, the Contractor must be able to provide the following electronic information for each required molecule: chemical structure or simplified molecular-input line-entry system (SMILES) or equivalent chemical structure information, supplier ID, plate ID, well location, tube ID, concentration in millimolar, and volume in microliters. This information shall be provided via email referencing individual compound vial barcodes. - The contractor must provide for shipping and handling to send small molecules in the provided vials to the NCATS. - Samples will be delivered as 4mg in barcoded tubes provided by NCATS. Quantity: Two (2) libraries with combined total of 8,118 compounds. (vii) Delivery Date: Delivery shall be made within forty-five (45) days after receipt of tubes from NCATS. Delivery Location: ATTN: Paul Shinn National Center for the Advancing Translational Sciences 9800 Medical Center Dr., Bldg. B Rockville, MD 20850 (viii) Evaluation Criteria: The Government will award a purchase order from this solicitation to the responsible offeror whose quote conforming to the solicitation will be most advantageous to the Government, price and other factors considered. The following factors shall be used to evaluate quotes: a) Technical capability of the item offered to meet the Government requirement; b) Price; and c) Past performance [see FAR 13.106-2(b)(3)]. (ix) The following provisions/clauses are incorporated by reference to this solicitation: - The provision at FAR 52.211-6, Brand Name or Equal (Aug 1999). - The provision at FAR 52.212-1, Instructions to Offerors -- Commercial Items (Aug 2018). - The provision at FAR 52.212-3, Offeror Representations and Certifications --Commercial Items (Aug 2018). This provision is provided in full text as an attachment to this solicitation. Offerors are to include a completed copy of the provision with its offer. - The clause at FAR 52.212-4, Contract Terms and Conditions -- Commercial Items (Jan 2017). - The clause at FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders -- Commercial Items (Aug 2018). This clause is provided in full text as an attachment to this solicitation. - The NIH Invoice and Payment Provisions (2/2014). These provisions are provided in full text as an attachment to this solicitation. (x) There are no additional contract requirement(s) or terms and conditions applicable to this acquisition. (xi) The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. (xii) Responses to this solicitation must include sufficient information to establish the interested parties' bona-fide capabilities of providing the product or service. The price quote shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s); product description; and any other information or factors that may be considered in the award decision. Such factors may include: past performance; special features required for effective program performance; trade-in considerations; probable life of the item selected as compared with that of a comparable item; warranty considerations; maintenance availability; and environmental and energy efficiency considerations. Respondents proposing on an equal product of the brand-name product specified in this announcement must provide, as part of their response: (a) product, catalog, model, and/or part number(s); (b) product description; (c) all relevant information and documentation that the item(s) offered meets the salient physical, functional, or performance characteristics as specified in the purchase description; quantity; estimated price or cost; shipping, handling, and/or installation charges; and delivery date after receipt of order. The Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. All responses must be received by or before 12:00 PM Eastern Daylight Time, Friday, September 14, 2018, and reference number NIHDA201800507. Responses must be submitted electronically to Mark McNally, Contract Specialist, at contact@example.gov. Fax responses will not be accepted. (xiii) The contact for information regarding this solicitation is Mark McNally, Contract Specialist, contact@example.gov, +1 (555) 000-0000.