Compound library of 509 bioactive compounds: MedChemExpress or brand-name equal

(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. (ii) The solicitation number is 75N95019Q00296 and the solicitation is issued as a request for quotation (RFQ). This acquisition is for a commercial item and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures and FAR Part 12-Acquisition of Commercial Items, and is not expected to exceed the simplified acquisition threshold. (iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2019-05, effective August 13, 2019. (iv) The associated NAICS code is 325414 and the small business size standard is 1,250 employees. This requirement is full and open with no set aside restrictions. Description (v) The National Center for Advancing Translational Sciences (NCATS) at the National Institues of Health (NIH) seeks to purchase a compound library of 509 bioactive compounds: MedChemExpress or brand-name equal. The specific 509 compounds are identified in the attached list and are all part of MedChemExpress' Bioactive Compound Library. See the attached list for the specific 509 compounds. The salient characteristics of the brand-name or equal compound library include: 1. Each compound must be provided in 10mg quantity. 2. Each compound must be provided as a powder (solid). 3. Each compound must have a confirmed purity of >90% (accuracy +/-5%). 4. The compound library must conform to drug-like parameters such as distribution of molecular weight, solubility, lipophilicity, hydrogen bond donors and acceptors. 5. The compounds must be replenishable. They must be available for resupply or resynthesis if needed for NCATS follow up in the future. The contractor must also provide the following information electronically for each individual compound. This information must be provided via email referencing individual compound vial barcodes: 1. Chemical structure or simplified molecular-input line-entry system (SMILES) or equivalent chemical structure information 2. Supplier ID 3. Plate ID 4. Well location 5. Tube ID 6. Concentration in millimolar 7. Volume in microliters (vi) Delivery is to occur within eight (8) weeks after receipt of vials supplied by NCATS. Delivery shall be made to the below address with FOB Destination, to the point of contact designated on the purchase order. National Center for the Advancement of Translational Sciences 9800 Medical Center Drive Rockville, MD 20850 Evaluation and Award (vii) The Government plans to award a contract resulting from this solicitation. The resulting award will be made to the responsible offeror whose offer will be most advantageous to the Government, price and other factors considered. The following factors shall be used to evaluate quotations: Technical Capability, Past Performance, and Price. Comparative evaluations will be conducted. (viii) A written notice of award or acceptance of an offer, mailed or otherwise furnished to the successful offeror within the time for acceptance specified in the offer, shall result in a binding contract without further action by either party. Before the offer's specified expiration time, the Government may accept an offer (or part of an offer), whether or not there are negotiations after its receipt, unless a written notice of withdrawal is received before award. (ix) The anticipated award date is August 29, 2019. Vendor and Submission Requirements (x) Offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. (xi) Responses to this solicitation must include sufficient information to establish the interested parties' bona-fide capabilities of performing the required service. Responses must also include the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), the certification of business size, and the completed offeror representation in FAR Provision 52.204-24 (attached). (xii) The price quote must include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, product or catalog number(s); product description; what the warranty covers; and any other information or factors that may be considered in the award decision. Such factors may include: past performance; special features required for effective program performance; trade-in considerations; probable life of the item selected as compared with that of a comparable item; warranty considerations; maintenance availability; and environmental and energy efficiency considerations. (xiii) All responses must be received by 8:59am EDT on August 26, 2019, and reference solicitation number 75N95019Q00296. Responses must be submitted via email to Kimberly Espinosa, Contract Specialist, at kimberly.espinosa@nih.gov, with a copy to Jeff Schmidt, Contracting Officer, at Jeffrey.schmidt@nih.gov. (xiv) For information regarding the solicitation, contact Kimberly Espinosa, Contract Specialist, at 301-827-3546 or kimberly.espinosa@nih.gov. (xv) All responsible sources may submit a quotation which shall be considered by the agency. Provisions and Clauses (xvi) The provision at FAR 52.252-1, Solicitation Provisions Incorporated by Reference (Feb 1998). This solicitation incorporates one or more solicitation provisions by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. The offeror is cautioned that the listed provisions may include blocks that must be completed by the offeror and submitted with its quotation or offer. In lieu of submitting the full text of those provisions, the offeror may identify the provision by paragraph identifier and provide the appropriate information with its quotation or offer. Also, the full text of a solicitation provision may be accessed electronically at this/these address(es): www.acquisition.gov. The following provisions apply to this acquisition and are incorporated by reference: - The provision at FAR 52.204-7, System for Award Management (Oct 2018) - The provision at FAR 52.204-16, Commercial and Government Entity Code Reporting (Jul 2016) - The provision at FAR 52.211-6, Brand Name or Equal (Aug 1999) - The provision at FAR 52.212-1, Instructions to Offerors - Commercial Items (Oct 2018) - The provision at 52.212-3, Offeror Representations and Certifications-Commercial Items (Oct 2018) (xvii) The clause at FAR 52.252-2, Clauses Incorporated by Reference (Feb 1998). This contract incorporates one or more clauses by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. Also, the full text of a clause may be accessed electronically at this/these address(es): www.acquisition.gov. In addition to the clauses checked in FAR 52.212-5 (attached), the following clauses also apply to this acquisition and are incorporated by reference: - The clause at FAR 52.204-13, System for Award Management Maintenance (Oct 2018) - The clause at FAR 52.204-18, Commercial and Government Entity Code Maintenance (Jul 2016) - The clause at FAR 52.212-4, Contract Terms and Conditions - Commercial Items (Oct 2018) - The clause at HHSAR 352.222-70, Contractor Cooperation in Equal Employement Opportunity Investigations (December 18, 2015) (xviii) The following provisions and clauses apply to this acquisition and are attached in full text: - The provision at FAR 52.204-24, Representation Regarding Certain Telecommunications and Video Surveillance Services or Equipment (Aug 2019) - Addendum to the clause at FAR 52.212-4, Contract Terms and Conditions - Commercial Items (Oct 2018) - The clause at FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders-Commercial Items (Aug 2019) - NIH Invoice and Payment Provisions (2/2014) (xix) There are no additional contract requirement(s) or terms and conditions applicable to this acquisition. (xx) The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement.