Development of Collaborative Research Facilities or Research-Resource Facilities (C06 Clinical Trial Not Allowed)

Notice of Funding Opportunity PAR-26-106, issued by the National Institutes of Health under the Department of Health and Human Services, solicits grant applications for the development or modernization of shared-use research facilities. The program is divided into two tracks: the Biomedical Research Facilities (BRF) program, which supports a broad range of basic, translational, clinical, or behavioral science research with funding between 2 million and 8 million dollars, and the HIV/AIDS Research Facilities (HRF) program, which focuses on resources aligned with the Office of AIDS Research priorities with funding between 2 million and 4 million dollars. The initiative aims to strengthen national research capacity by supporting core facilities, biorepositories, and shared research spaces, with a particular encouragement for applications from Institutions of Emerging Excellence. Applicants must adhere to strict technical and administrative requirements, including the submission of detailed line drawings, scientific justifications, and a budget with vendor quotes. Awardees are obligated to utilize the facility for its intended biomedical research purpose for at least 10 years following beneficial occupancy and must provide annual certifications of use for 20 years. Evaluation is conducted through a two-level NIH peer review process focusing on scientific merit, organizational coordination, and the functionality of the proposed design. Eligible organizations must maintain active registrations in the System for Award Management and eRA Commons, and all physical infrastructure must comply with federal and industry engineering standards as well as the NIST Cybersecurity framework for data protection.