Synthesis of Drugs/Chemical Substances

The Drug Enforcement Administration’s Office of Diversion Control is seeking qualified small businesses to provide synthesis of specific drugs and chemical substances under a combined synopsis/solicitation designated as a 100% Small Business Set-Aside, with the NAICS code 541380 and a size standard of $41.5 million. This procurement, identified by solicitation number 15DDHQ26P00000584, was amended on May 28, 2026, to revise the scope from DNA testing to the synthesis of eight specified chemical compounds in one-gram quantities, including Ethylflualprazolam, Etodezitramide, Spiroborphine, 2-Methyl-alpha-PiHP, Bezitramide, 4F-PV8, 5,6-Dichloro Brorphine (SR-14968), and 4-propanoyloxy-N,N-dimethyltryptamine, with an additional line item for shipping. Performance is required in West Palm Beach, Florida, and offers are due by 10:00 a.m. EST on June 5, 2026. Evaluation will follow a Lowest Price Technically Acceptable (LPTA) approach, where technical acceptability is a pass/fail gate based on the offeror’s demonstrated ability to synthesize all specified items, and award will be made to the lowest-priced responsible offeror meeting all technical requirements. The contract incorporates numerous FAR clauses related to labor standards, equal opportunity, accelerated payments to small business subcontractors, prohibitions on contracting with inverted domestic corporations, and protections under the Fair Labor Standards Act. The work involves access to classified National Security Information and Controlled Unclassified Information, requiring compliance with DOJ security protocols and potential security clearance requirements. Offerors must maintain current representations and certifications in SAM.gov and comply with Buy American Act provisions, traffick in persons prohibitions, and organizational conflict of interest disclosure obligations. All deliverables, including reports and materials, must be packaged in accordance with common commercial practices and clearly labeled with the contract number. Invoicing must follow strict requirements, including submission of itemized charges, delivery dates, taxpayer identification, and supporting documentation for travel, with payment due thirty days after deemed acceptance and disputed charges resolved through the FAR 52.212-4(d) Disputes clause. The Contracting Officer is Kenny Douangmala, and the