DoW Traumatic Brain Injury and Psychological Health, Clinical Trial Award
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The fiscal year 2026 Traumatic Brain Injury and Psychological Health Research Program Clinical Trial Award is designed to fund clinical trials that have the potential to significantly impact psychological health conditions and traumatic brain injury. This award supports a broad range of interventions, including new drugs, biologics, medical devices, diagnostics, therapies, and behavioral health strategies. Applicants must provide preliminary data and incorporate community-based participatory research approaches in their study design. The program offers funding at two research levels: Level 1 supports proof-of-principle pilot studies and early-phase clinical trials, while Level 2 funds larger-scale trials assessing effectiveness in patient populations. Additionally, there is an option for early-career investigators to partner with senior investigators, allowing both to receive separate awards if funded. The award is administered by the Department of the Army under the Department of Defense and emphasizes clinical trials as the core research mechanism. It ensures that funded projects are poised to transition findings into practical clinical applications, including healthcare products and practice guidelines. The program makes funding available to projects that demonstrate the potential for meaningful improvements in treatment or management of traumatic brain injury and psychological health conditions, reflecting its commitment to advancing clinical science in these critical areas. Contact information for further inquiries is provided through the eBRAP Help Desk.
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Full Description
Summary: The fiscal year 2026 (FY26) Traumatic Brain Injury and Psychological Health Research Program (TBIPHRP) Clinical Trial Award (CTA) intends to support clinical trials with the potential to have a significant impact on psychological health conditions and/or traumatic brain injury (TBI) through clinical applications, including health care products, technologies and/or practice guidelines.
Distinctive Features: Funding from this award mechanism must support a clinical trial.
· Clinical trials may be designed to evaluate a wide range of interventions, including new drugs, biologics, medical devices, diagnostics, therapies and behavioral health strategies.
· Preliminary data are required.
· The inclusion of community-based participatory research (CBPR) approaches is required.
· The CTA offers funding for two Research Levels. The applicant is responsible for selecting the Research Level based on the scope of the research.
○ Research Level 1: Supports proof-of-principle pilot studies, as well as phase 1 and phase 2 clinical trials.
○ Research Level 2: Supports larger-scale and advanced clinical trials that evaluate effectiveness in relevant patient populations.
· Early-Career Investigator Partnering Option (available for both Research Levels): This option accommodates two Principal Investigators (PIs), one of which is an Early-Career Investigator. If recommended for funding, each PI will receive a separate award.
