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Emergency Permit for Management of Hazardous Waste, Genentech, Inc. South Campus, South San Francisco, California

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The California Department of Toxic Substances Control has issued an Emergency Permit to Genentech, Inc. South Campus to safely stabilize a single 50-gram container of Sodium Amide that has developed hazardous peroxide formation on its container and cap, posing a significant risk of fire or explosion. Due to the imminent danger this unstable chemical presents to human health and the environment, the permit authorizes controlled chemical treatment to reduce its reactive and ignitable properties before transport. The stabilization process will be conducted by Advanced Chemical Transport LLC, doing business as Republic Services Inc., within a secure exclusion zone accessible only to trained technicians, following strict safety protocols to prevent accidents during handling and treatment. The activity is taking place at Genentech’s facility located at 340 Point San Bruno Boulevard in South San Francisco, California. The Emergency Permit is effective from July 2, 2026, through September 2, 2026, with the requirement that Genentech submit a final report within ten business days after permit expiration. This report must be certified in accordance with state regulations and confirm that all hazardous waste residuals from the treatment have been fully cleared from the area and properly managed. The decision to issue this emergency authorization stems from regulatory authority under Title 22 of the California Code of Regulations, ensuring compliance while addressing an urgent safety threat. Key points of contact for the permitting process include Parisa Khosraviani of DTSC, Daniel Fulford of Genentech, and Kevin Franco of Republic Services, ensuring coordinated oversight and accountability throughout the operation.

General Info

Genentech to stabilize hazardous sodium amide container at South San Francisco facility under emergency permit through September 2026.

Agency

California Toxic Substances Control, Department of

NAICS

562211 - Hazardous Waste Treatment and DisposalView NAICS

Place of Performance

South San Francisco, CA, 94080

Set-Aside

NONE

Documents

(1)

Emergency Permit for Hazardous Waste Management at Genentech South Campus

PDF•emergency-permit

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Timeline

PostedJul 2

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Organization & Contact Information

AgencyCalifornia Toxic Substances Control, Department of

Contacts3 people available

OfficeN/A

Organization / Agency

California Toxic Substances Control, Department of

Office AddressN/A

Contacts

Parisa KhosravianiHazardous Substances Engineer

contact@example.gov

+1 (555) 000-0000

Daniel FulfordSSF Site Services; SSHE, Hazardous Waste Senior Program Manager

contact@example.gov

+1 (555) 000-0000

Kevin FrancoEnvironmental Manager

contact@example.gov

+1 (555) 000-0000

Full Description

The California Department of Toxic Substances Control (DTSC), pursuant to authority granted under California Code of Regulations (CCR), Title 22, Division 4.5, Chapter 20, Sec. 66270.61, has issued an Emergency Permit to the Genentech, Inc. South Campus, ( EPA ID# CAR000182709) to treat hazardous waste through a controlled reaction with a chemical solution. Specifically, one (1) 50-gram container of Sodium Amide must be stabilized prior to transport to an authorized hazardous waste treatment, storage, and disposal facility. This chemical is currently being stored at Genentech, Inc. South Campus located at 340 Point San Bruno Boulevard, South San Francisco, California, 94080. DTSC has determined as a safety precaution to prevent an accident or severe injury, an Emergency Permit should be issued to chemically stabilize the hazardous waste prior to storage and eventual transportation off-site by Advanced Chemical Transport LLC (ACT), DBA Republic Services Inc. Background: The container has peroxide formation present on either the inside, outside, or the bottom of the chemical container, as well as the thread container cap. The presence of peroxide formation may be unstable at relatively low concentrations, resulting in fire and/or explosion if improperly handled. Due to the presence of peroxide formation, DTSC considers this chemical to be an imminent and substantial endangerment to human health and the environment. Chemical stabilization is recommended prior to transport to a permitted treatment, storage, and disposal facility. Project Activities: The treatment of this hazardous waste involves the addition of a solution to the container in a controlled manner to reduce the reactive or ignitable characteristics of the chemical. Treatment will take place within a designated exclusion zone. Only technicians from ACT will be allowed in the exclusion zone. Movement, preparation, and treatment of the containers will be in accordance with established standards. Within 10 business days of the expiration of this permit, Genentech, Inc. South Campus will submit a final report, signed in accordance with Title 22, CCR Sec. 66270.11(d). The report shall include certification that the treatment area has been cleared of all residual hazardous waste generated from this emergency treatment and all generated waste has been properly managed. The Emergency Permit is effective beginning July 2, 2026 and shall expire on September 2, 2026.