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This Solicitation opportunity from Department Of Defense was posted on August 25, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

FY2022-2026 DTRA Chemical / Biological Technologies Broad Agency Announcement

Closed
HDTRA122S0002Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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AI Contract Overview

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The FY2022-2026 DTRA Chemical/Biological Technologies Broad Agency Announcement (BAA), solicitation HDTRA122S0002, is a five-year open continuous vehicle designed to identify and select science and technology projects for transition into joint acquisition programs. Managed by the Defense Threat Reduction Agency (DTRA), the BAA focuses on advancing defense capabilities against chemical and biological warfare environments. The scope is specifically limited to projects within Technology Readiness Levels (TRL) 3-6, with the objective of achieving a TRL of 4-6 upon completion. Research areas include detection, digital battlespace management, protection, hazard mitigation, vaccines, medical diagnostics, and therapeutics. The BAA operates through individual topic calls, such as Call 3 for modeling and decision aids, Call 4 for porous surface detection, Call 5 for digital twins of sensors, Call 6 for broad-spectrum medical countermeasures, and Call 7 for autonomous biological aerosol collection triggers. Proposals are generally submitted in a phased approach (Phase I and Phase II) or a one-phase process, depending on the specific call. Evaluation is based on the overall benefit to the Government, prioritizing innovative technical approaches, alignment with Chemical and Biological Defense Program priorities, and the proposer's capability to perform. All submissions must be made electronically via the DTRA portal, and offerors must be registered in the System for Award Management (SAM).

General Info

Five-year DTRA BAA funds TRL 3-6 chemical, biological defense research with ongoing topic calls.

Agency

Department Of Defense → Defense Threat Reduction AgencyView Agency

NAICS

5417 - Scientific Research and Development Services

Place of Performance

VA

Set-Aside

NONE

Documents

(27)

CB BAA HDTRA122S0002 CALL 3 - Chemical and Biological Defense Modeling and Decision Aids

PDFsources-sought

TOPIC CALL 2 Q and A Phase I

PDFq-and-a

TOPIC CALL 4 Q and A Phase II

PDFq-and-a

DTRA Broad Agency Announcement Topics and Call 1

PDFpresolicitation

Annual Representations and Certifications (JAN 2025)

PDFreps-and-certs

CB BAA HD TRA122S0002 CALL 7 - Advanced Triggers for Autonomous Biological Aerosol Collection

PDFbaa-call

Cost Proposal Template

XLSXcost-proposal

Supplemental Volume Cover Sheet - BAA April 2024

PDFsupplemental-volume-cover-sheet

Attachment 2 - Statement of Work Template

PDFsow

DTRA HDTRA12250002 Topic Call 6 Q&A Phase I

PDFq-and-a

Pre-award Survey of Prospective Contractor Accounting System Checklist August 2025

PDFpre-award-survey

ROM Cost Estimate Template

XLSXrom

Data Rights Assertions List

DOCXdata-rights-assertions

Attachment 1: Technology Readiness Level (TRL) Definitions

PDFsow

TOPIC CALL 4 Q and A Phase I

PDFq-and-a

Topic Call 2 Phase II Q&A Document

PDFq-and-a

CB BAA HD TRA122S0002 CALL 6 Broad-Spectrum Medical Countermeasures

PDFbaa

HDTRA122S0002 CALL03 Proposal Submission and Evaluation Information

PDFproposal-submission-evaluation

Call 07 Q&A – Technical, Administrative, and Award Questions

PDFq-and-a

TOPIC CALL 5 Q and A Phase II

PDFq-and-a

CB BAA HDTRA122S0002 CALL 5 - Digital Twin for Chemical and Biological Sensors

PDFsources-sought

HDTRA122S0002 Broad Agency Announcement for Chemical/Biological Technologies

PDFbaa

TOPIC CALL 3 Q and A

PDFq-and-a

DTRA Topic Call 2 - Bioinformatics and Diagnostics Proposal Solicitation

PDFpresolicitation

CB BAA HDTRA122S0002 CALL 4 - Detection of Chemical Agents in Porous Surfaces

PDFbaa-call

TOPIC CALL 5 Q and A Phase I

PDFq-and-a

TOPIC CALL 1 Q and A Phase II

PDFq-and-a

AI Contract Breakdown

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Timeline

2 updates
PhaseClosed
Posted

Presolicitation

Response Deadline

Deadline has passed

Type Changed

Presolicitation → Solicitation

Amendment 1

Contract was updated

Amendment 2

Contract was updated

Submission Closed

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Organization & Contact Information

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AgencyDepartment Of Defense → Defense Threat Reduction Agency
Contacts1 person available
OfficeFORT BELVOIR, VA, 22060-6201, USA
Organization / Agency
Department Of Defense → Defense Threat Reduction Agency
View Agency Profile
Office AddressFORT BELVOIR, VA, 22060-6201, USA
Contacts
DTRA RD-CB BAA MAILBOX

Full Description

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UPDATED AUGUST 25, 2026: TOPIC CALL 7, QUESTIONS & ANSWERS (Q and A_Ph I) 


UPDATED JULY 8, 2026: TOPIC CALL 7


THE DEADLINE TO SUBMIT QUESTIONS RELATED TO THE TOPICS INCLUDED IN TOPIC CALL 7 IS JULY 22, 2026.


THE DEADLINE TO SUBMIT A PROPOSAL FOR THE TOPICS INCLUDED IN TOPIC CALL 7 IS SEPTEMBER 2, 2026 AT 2:00PM EDT.


UPDATED AUGUST 20, 2025: SECTIONS 4.8.2.3.1, 4.8.2.3.8, AND 9.0 OF THE BAA HAVE BEEN REVISED AND SECTION 4.8.2.3.17 HAS BEEN ADDED. ATTACHMENTS 6 AND 7 HAVE BEEN REVISED. 


UPDATED MARCH 11, 2025: TOPIC CALL 6, QUESTIONS & ANSWERS (Q and A_Ph I) 


UPDATED FEBRUARY 13, 2025: TOPIC CALL 6


THE DEADLINE TO SUBMIT QUESTIONS RELATED TO THE TOPICS INCLUDED IN TOPIC CALL 6 IS FEBRUARY 27, 2025.


THE DEADLINE TO SUBMIT A PROPOSAL FOR THE TOPICS INCLUDED IN TOPIC CALL 6 IS APRIL 10, 2025 AT 2:00PM EDT.


UPDATED AUGUST 30, 2024: TOPIC CALL 5, QUESTIONS & ANSWERS (Q and A_Ph II)


UPDATED AUGUST 30, 2024: TOPIC CALL 4, QUESTIONS & ANSWERS (Q and A_Ph II)


UPDATED JUNE 6, 2024: TOPIC CALL 5, QUESTIONS & ANSWERS (Q and A_PhI)


UPDATED MAY 10, 2024: TOPIC CALL 4, QUESTIONS & ANSWERS (Q and A_Ph I) 


UPDATED APRIL 30, 2024:  TOPIC CALL 5


THE DEADLINE TO SUBMIT QUESTIONS RELATED TO THE TOPIC INCLUDED IN TOPIC CALL 5 IS MAY 14, 2024.


THE DEADLINE TO SUBMIT A PROPOSAL FOR THE TOPIC INCLUDED IN TOPIC CALL 5 IS JUNE 25, 2024 AT 2:00PM EDT.


UPDATED APRIL 1, 2024:  TOPIC CALL 4


THE DEADLINE TO SUBMIT QUESTIONS RELATED TO TOPICS INCLUDED IN TOPIC CALL 4 IS APRIL 16, 2024.


THE DEADLINE TO SUBMIT A PROPOSAL FOR TOPICS INCLUDED IN TOPIC CALL 4 IS MAY 29, 2024 AT 2:00PM EDT.


UPDATED SEPTEMBER 29, 2023:  TOPIC CALL 3, QUESTIONS & ANSWERS (Q and A)


UPDATED SEPTEMBER 6, 2023: TOPIC CALL 3


THE DEADLINE TO SUBMIT QUESTIONS RELATED TO TOPICS INCLUDED IN TOPIC CALL 3 IS SEPTEMBER 18, 2023.


THE DEADLINE TO SUBMIT A PROPOSAL FOR TOPICS INCLUDED IN TOPIC CALL 3 IS OCTOBER 26, 2023 AT 2:00PM EDT. 


UPDATED AUGUST 14, 2023:  TOPIC CALL 2, QUESTIONS & ANSWERS (Q and A_Ph II)


UPDATED APRIL 24, 2023:  TOPIC CALL 2, QUESTIONS & ANSWERS (Q and A_Ph I) 


UPDATED MARCH 21, 2023:  TOPIC CALL 2


THE DEADLINE TO SUBMIT QUESTIONS RELATED TO TOPICS INCLUDED IN TOPIC CALL 2 IS MARCH 28, 2023.


THE DEADLINE TO SUBMIT A PHASE I PROPOSAL FOR TOPICS INCLUDED IN TOPIC CALL 2 IS MAY 10, 2023 AT 2:00PM EDT. 


UPDATED NOV 10, 2022: TOPIC CALL 1, QUESTIONS & ANSWERS (Q and A_Ph II)


The purpose of this BAA is to serve as a five-year (60-month) open continuous vehicle through which topics will be released as individual calls as they become available during the BAA open period. This BAA will remain open for five years from the date of release.


The scope of this BAA is limited to projects that meet Technology Readiness Level (TRL) definitions in the TRL range of 3-6 (see ATTACHMENT 1 for TRL definitions). Upon completion of the proposed development efforts, solutions should strive to meet a TRL in the range of 4-6. Proposals that address technologies at TRL 4 or greater should also be aware of the Manufacturing Readiness Level (MRL) considerations.


The DTRA RD-CB mission was established by the Department of Defense (DoD) to provide state-of-the-art defense capabilities to allow military forces of the United States to operate and to successfully complete their missions in chemical and biological warfare environments. The scope of mission efforts and the priorities assigned to specific projects are influenced by changes in military and civilian Chemical and Biological Defense (CBD) science and technology, advanced developments, operational requirements, military threat assessments, and national defense strategies. To keep pace with defense capability requirements, the CBD Program (CBDP), as part of its mission, routinely promulgates chemical and biological research. The comprehensive research program encompasses both intramural and extramural sources, and the role of each is vital to the fulfillment of the CBDP objectives.


DTRA is seeking optimum approaches to meet technology objectives with a goal to identify and select science and technology projects that can be transitioned to joint acquisition programs.

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