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This Government Contract opportunity was posted on June 3, 2008. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

Genetic Modification of Orange Tissues

Awarded
AG-6395-S-08-0059Federal

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The United States Department of Agriculture Center for Plant Health Science and Technology is seeking a qualified scientific laboratory to develop genetically modified Valencia and Hamlin orange tissue germplasm. The primary goal is to create citrus plants that express specific genes to impede the growth of the Candidatus Liberibacter asiaticus pathogen, which causes Citrus Greening. This initiative is critical for the long-term viability of the Florida citrus industry, as current pesticides and natural resistances are ineffective against the disease and its psyllid vector. The selected contractor must produce the transformed germplasm within an 18 month window and demonstrate resistance to the pathogen found in commercial groves. Required qualifications include extensive experience in citrus transformation technologies, the ability to manipulate antimicrobial genes, and the possession of necessary regulatory permits and facilities for Select Agent research. This project is managed under solicitation number AG-6395-S-08-0059 and falls under NAICS code 541711.

General Info

Agency

N/A

Contract Value

$275,998.85

NAICS

541711 - Research and Development in Biotechnology

Place of Performance

FL, USA

Set-Aside

NONE

Award Issued Date

Documents

0

No documents available

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Timeline

4 updates
PhaseAwarded
Posted

Sources Sought

Notice updated

Response deadline changed from Apr 15, 2008 to Apr 24, 2008. The notice description changed.

Notice updated

The notice description changed.

Deadline changed

Response deadline changed from Apr 24, 2008 to May 8, 2008.

Notice updated

Response deadline time changed from 9:00 PM UTC to 8:00 PM UTC on May 8, 2008. The notice description changed.

Awarded

Contract was awarded

Submission Closed

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Organization & Contact Information

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AgencyN/A
Contacts1 person available
OfficeN/A
Organization / Agency
N/A
Office AddressN/A
Contacts
Nathan JohnsonContract Specialist

Full Description

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Background The United States Department of Agriculture - Center for Plant Health Science & Technology (CPHST), is the scientific support agency of the Animal Plant Health Inspection Service, Plant Protection and Quarantine division. Plant Protection and Quarantine is responsible for safeguarding American agriculture from exotic pests and diseases and to provide response to incursions by eradication or containment. The high consequence exotic Citrus Greening pathogen, Candidatus Liberibacter asiaticus, was discovered in Florida 2005 and is now established throughout the major citrus growing regions of the state. Through the Citrus Health Response Plan, CPHST leads the effort to limit spread of this pathogen within Florida and to other citrus growing states where the pathogen is not present. There is no known source of viable resistance in Citrus species to Citrus Greening, and pesticides to the pathogen or to its psyllid vector is not effective in disease prevention. Citrus growing regions that have high prevalence of Citrus Greening become unproductive after a few years and this is anticipated to occur in Florida as disease prevalence increases. The future viability of the Florida citrus industry is dependent on finding a suitable means of production in the presence of the Citrus Greening Pathogen. It is imperative that a durable means of growing citrus that remains productive long enough for sustainable harvest be found. At this time, the development of resistant citrus germplasm through genetic engineering provides the most likely means of achieving this goal. Objective To produce within an 18 month window mature Valencia and Hamlin orange tissue germplasm transformed (genetically modified) to express an array of genes designed to impede growth of pathogenic bacteria specifically to provide demonstrated resistance to the Citrus Greening pathogen present in Florida commercial citrus groves. Qualifications At minimum a qualified scientific laboratory will meet the following qualifications: - Experience at transformation of a variety of plant hosts with suitable - freedom-to-operate for engineering technologies for Citrus species o Development of transformation technologies of physiologically mature Citrus - Demonstrated ability to manipulate genes with antimicrobial properties: o Suitable - freedom-to-operate a variety of genes with demonstrated antimicrobial activities o Demonstration of experience and data that quantify parameters of antimicrobial efficacy of system o Ability to test and identify high resistance to Citrus Greening pathogen in Citrus hosts - Facilities suitable for Select Agent research and regulatory permits in place for experimentation with Citrus Greening pathogen Candidatus Liberibacter asiaticus Solicitation Availability The solicitation should be available on or about 24 April 2008 with an estimated proposal due date 20 days after solicitation posting.

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