This Sources Sought opportunity from Department Of Agriculture was posted on November 16, 2020. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Global Metabolomics on Fetal Liver

Awarded

12805B21Q0018Federal

Submission Closed11/19/2020, 12:00:00 AM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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DEADLINE

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AI Contract Overview

The United States Department of Agriculture's Meat Animal Research Center is seeking information from capable vendors for global metabolomics services on fetal liver samples in Clay Center, Nebraska. This sources sought notice, under NAICS code 541715, aims to support research into how maternal mineral and energy supplementation during early pregnancy affects fetal liver metabolism to benefit the beef, sheep, and swine industries. Interested parties must provide their company capabilities and business size status to assist the government in market research for a future solicitation. The technical requirements specify the use of non-targeted UHPLC-MS/MS in both positive and negative ion modes, utilizing multiple analysis methods including HILIC to cover a diverse range of metabolites. The selected provider must deliver relative concentration profiles for 1,000 to 25,000 metabolites per sample, comprehensive statistical analysis involving t-tests and ANOVA, and a summary biochemical interpretation report. Deliverables must include publication-ready tables and figures, detailed analytical method outlines, and access to data visualization tools for further exploration.

General Info

Agency

Department Of Agriculture → USDA Ars Pa Aao Acq/per Prop

Contract Value

$19,260.15

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

Clay Center, NE, 68933, USA

Set-Aside

NONE

Awardee

METABOLON, INC.

Award Issued Date

12/08/2020, 12:00:00 AM UTC

Documents

No documents available

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Timeline

PhaseAwarded

PostedNov 16

Sources Sought

AwardedDec 8

Contract was awarded

Submission Closed

11/19/2020, 12:00:00 AM UTC

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Organization & Contact Information

AgencyDepartment Of Agriculture → USDA Ars Pa Aao Acq/per Prop

Contacts1 person available

OfficeFORT COLLINS, CO, 80526, USA

Organization / AgencyDepartment Of Agriculture → USDA Ars Pa Aao Acq/per Prop

Office AddressFORT COLLINS, CO, 80526, USA

Contacts

Diane Gamboa

contact@example.gov

+1 (555) 000-0000

Full Description

The United States Department of Agriculture (USDA), U.S. Meat Animal Research Center (USMARC), has a requirement for Global Metabolomics on Fetal Liver in Clay Center, NE. The NAICS Code is 541715. In response to this sources sought please submit information on your company's capabilities to provide this service. Please also provide information on whether your company is a small or large business in accordance with the NAICS code listed. The Government acknowledges that responses to this sources sought are not binding offers. The information obtained will assist in our market research and future solicitation processes. The purpose of this sources sought is solely to obtain information and sources for our future requirement. Background: Scientists are developing scientific information and new technology to solve high priority problems for the U.S. beef, sheep, and swine industries. As part of the effort, they require global metabolomics using UHPLC-MS/MS in positive and negative ion mode on fetal liver samples to assess the effects of maternal mineral and energy supplementation during early pregnancy on fetal liver metabolism. Technical Requirements/Tasks: Non-targeted UPLC-MS using multiple analysis methods to cover a diverse class of metabolites and provide the following analysis: Sample Preparation Multiple Analysis methods including: UHPLC-MS/MS(+ESI)1, UHPLC-MS/MS(+ESI)2, UHPLC-MS/MS(-ESI), UHPLC (HILIC)-MS/MS. A relative concentration profile of all structurally named small-molecule entities, which can include both endogenous compounds, xenobiotics, and their metabolites, extracted from the samples and detected by an HD4 Global Metabolomics platform. Coverage depth up to 1000 to 25000 metabolites/samples A statistical analysis of the resulting data, which consists of univariate significance tests (t-tests and ANOVA). Summary biochemical interpretation of selected, statistically significant metabolites provided in a Word report. An outline of the analytical methods. Access to downloadable study deliverables. Access to data analysis and visualization tools that allow for further data exploration. Publication ready tables and figures.