This Solicitation opportunity from Government of Canada was posted on November 25, 2025. The submission period has ended. Browse the details below for market research, or find similar active opportunities.
High throughput device for rapid cellular metabolic characterization
Closed
25-58185CanadaSubmission Closed
Contract Overview
Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.
General Info
Agency
Government of Canada → National Research Council of CanadaView Agency
NAICS
N/A
Place of Performance
*Canada, CANSet-Aside
NONE
Documents
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Timeline
PhaseClosed
Submission Closed
Organization & Contact Information
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AgencyGovernment of Canada → National Research Council of Canada
Contacts1 person available
OfficeN/A
Office AddressN/A
Contacts
Full Description
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Description:
OBJECTIVE:
The cell culture scale-up team (CCSU) has a requirement for an instrument for rapid cellular metabolic characterization. The instrument will be used to characterize and screen the phenotype and the metabolic requirements of cell lines developed at the NRC and used in large-scale bioreactors.
BACKGROUND:
Cell lines can be used to produce monoclonal antibodies, recombinant proteins, viral vectors, vaccines, viruses and virus-like-particles. In large-scale bioreactor, the metabolic profile of a cell line has a critical impact on its productivity. The presence of certain nutrients in the cell culture media is also a strong determinant of the cell line performance. Therefore, we are looking for an instrument that will enable measurements of multiple metabolites in parallel at 32oC to 37oC in live cells. We are particularly interested in measurements of metabolites involved in mitochondrial activity and respiration. We also need to screen different compounds that might improve cell growth and productivity in a high-throughput fashion.
All the deliverables must be received within 2 months after the contract award date.
